(28 nodes) Mixed, incl. 14-3-3 domain, and Peptidase S54, rhomboid network (Manihot esculenta)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	A0A251JQH2	Receptor-like serine/threonine-protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (785 aa)
	A0A2C9U179	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (232 aa)
	A0A2C9U4Y8	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. (329 aa)
	A0A2C9UEK9	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (260 aa)
	A0A2C9UJ83	RHOMBOID-like protein. (275 aa)
	A0A2C9UPE4	Receptor-like serine/threonine-protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (783 aa)
	A0A2C9UWS3	Protein kinase domain-containing protein. (503 aa)
	A0A2C9UY85	Uncharacterized protein. (649 aa)
	A0A2C9V281	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. (291 aa)
	A0A2C9V3J2	Xyloglucan endotransglucosylase/hydrolase; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Belongs to the glycosyl hydrolase 16 family. (291 aa)
	A0A2C9V8M0	Xyloglucan endotransglucosylase/hydrolase; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Belongs to the glycosyl hydrolase 16 family. (294 aa)
	A0A2C9V9Y0	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. (321 aa)
	A0A2C9VCF1	Xyloglucan endotransglucosylase/hydrolase; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Belongs to the glycosyl hydrolase 16 family. (294 aa)
	A0A2C9VG56	Uncharacterized protein. (212 aa)
	A0A2C9VLA8	Uncharacterized protein. (220 aa)
	A0A2C9VLB0	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. (316 aa)
	A0A2C9VPA2	Expansin; Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. Belongs to the expansin family. Expansin A subfamily. (208 aa)
	A0A2C9VT91	RHOMBOID-like protein. (329 aa)
	A0A2C9VWH3	Expansin; Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. Belongs to the expansin family. Expansin A subfamily. (251 aa)
	A0A2C9VXK7	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (264 aa)
	A0A2C9VYP9	Xyloglucan endotransglucosylase/hydrolase; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Belongs to the glycosyl hydrolase 16 family. (290 aa)
	A0A2C9W5T0	Expansin; Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. Belongs to the expansin family. Expansin A subfamily. (248 aa)
	A0A2C9WAE8	RHOMBOID-like protein. (320 aa)
	A0A2C9WC89	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (258 aa)
	A0A2C9WE61	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (253 aa)
	A0A2C9WEW1	Uncharacterized protein. (746 aa)
	A0A2C9WHB1	Expansin; Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. Belongs to the expansin family. Expansin A subfamily. (250 aa)
	A0A2C9WIN9	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (236 aa)

Your Current Organism:

Manihot esculenta

NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2C9U179	A0A2C9U4Y8	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.	0.472
A0A2C9U179	A0A2C9UJ83	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	RHOMBOID-like protein.	0.457
A0A2C9U179	A0A2C9V8M0	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Xyloglucan endotransglucosylase/hydrolase; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Belongs to the glycosyl hydrolase 16 family.	0.457
A0A2C9U179	A0A2C9V9Y0	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.	0.472
A0A2C9U179	A0A2C9VCF1	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Xyloglucan endotransglucosylase/hydrolase; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Belongs to the glycosyl hydrolase 16 family.	0.457
A0A2C9U179	A0A2C9VG56	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Uncharacterized protein.	0.452
A0A2C9U179	A0A2C9VT91	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	RHOMBOID-like protein.	0.457
A0A2C9U179	A0A2C9W5T0	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Expansin; Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. Belongs to the expansin family. Expansin A subfamily.	0.414
A0A2C9U179	A0A2C9WAE8	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	RHOMBOID-like protein.	0.556
A0A2C9U4Y8	A0A2C9U179	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.472
A0A2C9U4Y8	A0A2C9V3J2	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.	Xyloglucan endotransglucosylase/hydrolase; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Belongs to the glycosyl hydrolase 16 family.	0.418
A0A2C9U4Y8	A0A2C9V8M0	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.	Xyloglucan endotransglucosylase/hydrolase; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Belongs to the glycosyl hydrolase 16 family.	0.480
A0A2C9U4Y8	A0A2C9VCF1	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.	Xyloglucan endotransglucosylase/hydrolase; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Belongs to the glycosyl hydrolase 16 family.	0.480
A0A2C9U4Y8	A0A2C9VWH3	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.	Expansin; Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. Belongs to the expansin family. Expansin A subfamily.	0.508
A0A2C9U4Y8	A0A2C9VYP9	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.	Xyloglucan endotransglucosylase/hydrolase; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Belongs to the glycosyl hydrolase 16 family.	0.418
A0A2C9U4Y8	A0A2C9W5T0	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.	Expansin; Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. Belongs to the expansin family. Expansin A subfamily.	0.561
A0A2C9U4Y8	A0A2C9WE61	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.472
A0A2C9U4Y8	A0A2C9WHB1	Peroxidase; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.	Expansin; Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. Belongs to the expansin family. Expansin A subfamily.	0.508
A0A2C9UJ83	A0A2C9U179	RHOMBOID-like protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.457
A0A2C9UJ83	A0A2C9VG56	RHOMBOID-like protein.	Uncharacterized protein.	0.432