STRINGSTRING
A0A251JK67 A0A251JK67 A0A251JT29 A0A251JT29 A0A251JWR0 A0A251JWR0 FEN1 FEN1 A0A251KDB2 A0A251KDB2 FEN1-2 FEN1-2 A0A2C9U2G1 A0A2C9U2G1 A0A2C9U5A0 A0A2C9U5A0 A0A2C9U9R7 A0A2C9U9R7 A0A2C9UMR5 A0A2C9UMR5 A0A2C9UMT0 A0A2C9UMT0 A0A2C9UQC0 A0A2C9UQC0 A0A2C9UTS3 A0A2C9UTS3 A0A2C9V0Y5 A0A2C9V0Y5 A0A2C9V1W9 A0A2C9V1W9 A0A2C9V8D2 A0A2C9V8D2 A0A2C9VEK0 A0A2C9VEK0 A0A2C9VHU3 A0A2C9VHU3 A0A2C9VLV1 A0A2C9VLV1 A0A2C9VPX4 A0A2C9VPX4 A0A2C9VYJ6 A0A2C9VYJ6 A0A2C9VZY1 A0A2C9VZY1 A0A2C9W647 A0A2C9W647 A0A2C9WAM4 A0A2C9WAM4 A0A2C9WD70 A0A2C9WD70 A0A2C9WEA4 A0A2C9WEA4 A0A2C9WEG8 A0A2C9WEG8 A0A2C9WEK2 A0A2C9WEK2 A0A2C9WKY2 A0A2C9WKY2 A0A2C9WLH4 A0A2C9WLH4 A0A2C9WN70 A0A2C9WN70 A0A2C9WN82 A0A2C9WN82 A0A2C9WP85 A0A2C9WP85
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A251JK67DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (458 aa)
A0A251JT29Checkpoint protein; Belongs to the HUS1 family. (320 aa)
A0A251JWR0DNA ligase. (804 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (383 aa)
A0A251KDB2Uncharacterized protein; Belongs to the rad9 family. (447 aa)
FEN1-2Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (415 aa)
A0A2C9U2G1Rep_fac_C domain-containing protein. (252 aa)
A0A2C9U5A0AAA domain-containing protein. (1195 aa)
A0A2C9U9R7AAA domain-containing protein. (1193 aa)
A0A2C9UMR5AAA domain-containing protein. (1284 aa)
A0A2C9UMT0DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (458 aa)
A0A2C9UQC0Protein kinase domain-containing protein. (329 aa)
A0A2C9UTS3DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (621 aa)
A0A2C9V0Y5DNA primase; Belongs to the eukaryotic-type primase small subunit family. (450 aa)
A0A2C9V1W9CBFD_NFYB_HMF domain-containing protein. (161 aa)
A0A2C9V8D2Uncharacterized protein. (650 aa)
A0A2C9VEK0Uncharacterized protein. (429 aa)
A0A2C9VHU3AAA domain-containing protein. (354 aa)
A0A2C9VLV1AAA domain-containing protein. (1262 aa)
A0A2C9VPX4AAA domain-containing protein. (1034 aa)
A0A2C9VYJ6DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2223 aa)
A0A2C9VZY1Replication factor C subunit 1. (984 aa)
A0A2C9W647DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (533 aa)
A0A2C9WAM4AAA domain-containing protein. (335 aa)
A0A2C9WD70Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (264 aa)
A0A2C9WEA4DNA ligase. (1217 aa)
A0A2C9WEG8ATPase_AAA_core domain-containing protein. (1256 aa)
A0A2C9WEK2AAA domain-containing protein. (342 aa)
A0A2C9WKY2DDT domain-containing protein. (715 aa)
A0A2C9WLH4Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (266 aa)
A0A2C9WN70Uncharacterized protein. (789 aa)
A0A2C9WN82Uncharacterized protein. (612 aa)
A0A2C9WP85Uncharacterized protein. (617 aa)
Your Current Organism:
Manihot esculenta
NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.