(6 nodes) DNA replication factor C complex, and PCNA complex network (Manihot esculenta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2C9VHU3	AAA domain-containing protein. (354 aa)
	A0A2C9VLV1	AAA domain-containing protein. (1262 aa)
	A0A2C9VZY1	Replication factor C subunit 1. (984 aa)
	A0A2C9WEA4	DNA ligase. (1217 aa)
	A0A2C9WLH4	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (266 aa)
	A0A2C9WP85	Uncharacterized protein. (617 aa)

Your Current Organism:

Manihot esculenta

NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2C9VHU3	A0A2C9VLV1	AAA domain-containing protein.	AAA domain-containing protein.	0.968
A0A2C9VHU3	A0A2C9VZY1	AAA domain-containing protein.	Replication factor C subunit 1.	0.984
A0A2C9VHU3	A0A2C9WEA4	AAA domain-containing protein.	DNA ligase.	0.882
A0A2C9VHU3	A0A2C9WLH4	AAA domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.980
A0A2C9VHU3	A0A2C9WP85	AAA domain-containing protein.	Uncharacterized protein.	0.813
A0A2C9VLV1	A0A2C9VHU3	AAA domain-containing protein.	AAA domain-containing protein.	0.968
A0A2C9VLV1	A0A2C9VZY1	AAA domain-containing protein.	Replication factor C subunit 1.	0.931
A0A2C9VLV1	A0A2C9WEA4	AAA domain-containing protein.	DNA ligase.	0.837
A0A2C9VLV1	A0A2C9WLH4	AAA domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.955
A0A2C9VLV1	A0A2C9WP85	AAA domain-containing protein.	Uncharacterized protein.	0.701
A0A2C9VZY1	A0A2C9VHU3	Replication factor C subunit 1.	AAA domain-containing protein.	0.984
A0A2C9VZY1	A0A2C9VLV1	Replication factor C subunit 1.	AAA domain-containing protein.	0.931
A0A2C9VZY1	A0A2C9WEA4	Replication factor C subunit 1.	DNA ligase.	0.903
A0A2C9VZY1	A0A2C9WLH4	Replication factor C subunit 1.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.977
A0A2C9VZY1	A0A2C9WP85	Replication factor C subunit 1.	Uncharacterized protein.	0.872
A0A2C9WEA4	A0A2C9VHU3	DNA ligase.	AAA domain-containing protein.	0.882
A0A2C9WEA4	A0A2C9VLV1	DNA ligase.	AAA domain-containing protein.	0.837
A0A2C9WEA4	A0A2C9VZY1	DNA ligase.	Replication factor C subunit 1.	0.903
A0A2C9WEA4	A0A2C9WLH4	DNA ligase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.997
A0A2C9WEA4	A0A2C9WP85	DNA ligase.	Uncharacterized protein.	0.983