(16 nodes) Sensing of DNA Double Strand Breaks, and HDR through Single Strand Annealing (SSA) network (Manihot esculenta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A251K0S2	Uncharacterized protein. (1230 aa)
	A0A251KP80	PWWP domain-containing protein. (1099 aa)
	A0A2C9TZF7	Helicase ATP-binding domain-containing protein. (660 aa)
	A0A2C9U6C5	Uncharacterized protein. (758 aa)
	A0A2C9UEA6	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (731 aa)
	A0A2C9VPP1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2526 aa)
	A0A2C9VTN6	Uncharacterized protein. (1269 aa)
	A0A2C9W0D7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2430 aa)
	A0A2C9W697	Ku_C domain-containing protein. (97 aa)
	A0A2C9W8C7	Uncharacterized protein; Belongs to the RecA family. (367 aa)
	A0A2C9W8Z1	Zinc-hook domain-containing protein. (1316 aa)
	A0A2C9WDU3	DDT domain-containing protein. (714 aa)
	A0A2C9WEQ0	Uncharacterized protein. (947 aa)
	A0A2C9WKB7	Uncharacterized protein. (538 aa)
	A0A2C9WM87	Uncharacterized protein. (534 aa)
	A0A2C9WQV8	Uncharacterized protein. (1224 aa)

Your Current Organism:

Manihot esculenta

NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A251K0S2	A0A251KP80	Uncharacterized protein.	PWWP domain-containing protein.	0.706
A0A251K0S2	A0A2C9TZF7	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.604
A0A251K0S2	A0A2C9U6C5	Uncharacterized protein.	Uncharacterized protein.	0.926
A0A251K0S2	A0A2C9UEA6	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.849
A0A251K0S2	A0A2C9VPP1	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.706
A0A251K0S2	A0A2C9VTN6	Uncharacterized protein.	Uncharacterized protein.	0.916
A0A251K0S2	A0A2C9W0D7	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.849
A0A251K0S2	A0A2C9W697	Uncharacterized protein.	Ku_C domain-containing protein.	0.742
A0A251K0S2	A0A2C9W8C7	Uncharacterized protein.	Uncharacterized protein; Belongs to the RecA family.	0.802
A0A251K0S2	A0A2C9W8Z1	Uncharacterized protein.	Zinc-hook domain-containing protein.	0.873
A0A251K0S2	A0A2C9WDU3	Uncharacterized protein.	DDT domain-containing protein.	0.576
A0A251K0S2	A0A2C9WEQ0	Uncharacterized protein.	Uncharacterized protein.	0.623
A0A251K0S2	A0A2C9WKB7	Uncharacterized protein.	Uncharacterized protein.	0.641
A0A251K0S2	A0A2C9WM87	Uncharacterized protein.	Uncharacterized protein.	0.686
A0A251K0S2	A0A2C9WQV8	Uncharacterized protein.	Uncharacterized protein.	0.623
A0A251KP80	A0A251K0S2	PWWP domain-containing protein.	Uncharacterized protein.	0.706
A0A251KP80	A0A2C9TZF7	PWWP domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.757
A0A251KP80	A0A2C9U6C5	PWWP domain-containing protein.	Uncharacterized protein.	0.827
A0A251KP80	A0A2C9UEA6	PWWP domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.956
A0A251KP80	A0A2C9VTN6	PWWP domain-containing protein.	Uncharacterized protein.	0.915