(84 nodes) DNA duplex unwinding network (Manihot esculenta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2C9VFJ8	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (879 aa)
	A0A2C9U7K7	UBA domain-containing protein. (554 aa)
	A0A2C9U7Z9	Uncharacterized protein. (1273 aa)
	A0A2C9U983	DNA helicase; Belongs to the MCM family. (840 aa)
	A0A2C9UC71	Uncharacterized protein. (1120 aa)
	A0A2C9UFC3	Uncharacterized protein. (1018 aa)
	A0A2C9UFY8	Uncharacterized protein. (1980 aa)
	A0A2C9UG82	DNA helicase; Belongs to the MCM family. (763 aa)
	A0A2C9UHM1	Uncharacterized protein. (132 aa)
	A0A2C9UIJ8	Uncharacterized protein. (1138 aa)
	A0A2C9UJK2	UvrD-like helicase C-terminal domain-containing protein. (405 aa)
	A0A2C9ULC1	SF4 helicase domain-containing protein. (694 aa)
	A0A2C9UP24	Uncharacterized protein. (891 aa)
	A0A2C9UQ53	ATP-dependent DNA helicase; Belongs to the helicase family. (355 aa)
	A0A2C9UQK4	RuvB-like helicase; Belongs to the RuvB family. (467 aa)
	A0A2C9UV41	ATP-dependent DNA helicase; Belongs to the helicase family. (269 aa)
	A0A2C9UYK0	Helicase ATP-binding domain-containing protein. (1044 aa)
	A0A2C9UZ96	ATP-dependent DNA helicase; Belongs to the helicase family. (211 aa)
	A0A2C9UZB7	Uncharacterized protein. (830 aa)
	A0A2C9UZL5	Helicase ATP-binding domain-containing protein. (914 aa)
	A0A2C9UZX5	Uncharacterized protein. (191 aa)
	A0A2C9V464	Helitron_like_N domain-containing protein. (355 aa)
	A0A2C9V511	MCM domain-containing protein; Belongs to the MCM family. (664 aa)
	A0A2C9V5J4	ATP-dependent DNA helicase; Belongs to the helicase family. (136 aa)
	A0A2C9V8U0	Uncharacterized protein. (649 aa)
	A0A2C9VC38	MCM domain-containing protein; Belongs to the MCM family. (797 aa)
	A0A2C9VEH9	Uncharacterized protein. (220 aa)
	A0A2C9VEZ5	DNA helicase; Belongs to the MCM family. (942 aa)
	A0A2C9U7G9	Uncharacterized protein. (91 aa)
	A0A2C9VGP9	Uncharacterized protein. (981 aa)
	A0A2C9VMV9	DNA helicase; Belongs to the MCM family. (726 aa)
	A0A2C9VNV9	Uncharacterized protein. (1111 aa)
	A0A2C9VP39	Uncharacterized protein. (2037 aa)
	A0A2C9VP72	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (624 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (718 aa)
	A0A2C9VSX6	Uncharacterized protein. (2243 aa)
	A0A2C9VTN6	Uncharacterized protein. (1269 aa)
	A0A2C9VU83	Helicase ATP-binding domain-containing protein. (758 aa)
	A0A2C9VZN6	RuvB-like helicase; Belongs to the RuvB family. (458 aa)
	A0A2C9W010	HD domain-containing protein. (223 aa)
	A0A2C9W0A1	Uncharacterized protein. (390 aa)
	A0A2C9W1V4	Uncharacterized protein. (184 aa)
	A0A2C9W626	SAP domain-containing protein. (628 aa)
	A0A2C9W697	Ku_C domain-containing protein. (97 aa)
	A0A2C9W6U2	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (668 aa)
	A0A251JLM6	Uncharacterized protein. (500 aa)
	A0A2C9W712	ATP-dependent DNA helicase; Belongs to the helicase family. (125 aa)
	A0A2C9W7H0	Uncharacterized protein. (531 aa)
	A0A2C9W8Z1	Zinc-hook domain-containing protein. (1316 aa)
	A0A2C9WA40	Uncharacterized protein. (1117 aa)
	A0A2C9WAX3	Uncharacterized protein. (571 aa)
	A0A2C9WC44	ATP-dependent DNA helicase; Belongs to the helicase family. (510 aa)
	A0A2C9WCA0	Uncharacterized protein. (756 aa)
	A0A2C9WCA9	Uncharacterized protein. (474 aa)
	A0A2C9WCR0	Uncharacterized protein. (248 aa)
	A0A2C9WCR4	Uncharacterized protein. (768 aa)
	A0A2C9WKB5	Uncharacterized protein. (1230 aa)
	A0A2C9WKJ9	Uncharacterized protein. (474 aa)
	A0A2C9WKY3	Uncharacterized protein. (667 aa)
	A0A2C9WL27	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (724 aa)
	A0A2C9WNH0	Uncharacterized protein. (246 aa)
	A0A2C9WP57	Uncharacterized protein. (2243 aa)
	A0A2C9WPG1	Uncharacterized protein. (1031 aa)
	MCM7-2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (564 aa)
	A0A2C9WRX9	ATP-dependent DNA helicase 2 subunit KU80; Single-stranded DNA-dependent ATP-dependent helicase. (705 aa)
	A0A251JNV0	RuvB-like helicase; Belongs to the RuvB family. (467 aa)
	A0A251K0S2	Uncharacterized protein. (1230 aa)
	A0A251K809	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (614 aa)
	A0A2C9TZF7	Helicase ATP-binding domain-containing protein. (660 aa)
	A0A2C9U247	Uncharacterized protein. (200 aa)
	A0A2C9U2A6	Uncharacterized protein. (1406 aa)
	A0A2C9U3K4	ATP-dependent DNA helicase; Belongs to the helicase family. (331 aa)
	A0A2C9U3P5	CCHC-type domain-containing protein. (163 aa)
	A0A2C9U3V5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (707 aa)
	A0A2C9U463	Helitron_like_N domain-containing protein. (115 aa)
	A0A2C9U592	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (849 aa)
	A0A251JG04	Uncharacterized protein. (493 aa)
	A0A251J350	Uncharacterized protein. (542 aa)
	MANES_S011500	ATP-dependent DNA helicase; Belongs to the helicase family. (166 aa)
	MANES_S029600	Uncharacterized protein. (112 aa)
	MANES_S029800	Uncharacterized protein. (99 aa)
	MANES_S101400	DNA helicase; Belongs to the MCM family. (833 aa)
	A0A2C9U658	Uncharacterized protein. (148 aa)
	A0A2C9U6P1	DNA helicase; Belongs to the MCM family. (768 aa)

Your Current Organism:

Manihot esculenta

NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A251J350	A0A2C9TZF7	A0A251J350	A0A2C9TZF7	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.855
A0A251J350	A0A2C9UYK0	A0A251J350	A0A2C9UYK0	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.855
A0A251J350	A0A2C9UZL5	A0A251J350	A0A2C9UZL5	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.864
A0A251J350	A0A2C9VU83	A0A251J350	A0A2C9VU83	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.969
A0A251JG04	A0A2C9TZF7	A0A251JG04	A0A2C9TZF7	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.855
A0A251JG04	A0A2C9UYK0	A0A251JG04	A0A2C9UYK0	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.855
A0A251JG04	A0A2C9UZL5	A0A251JG04	A0A2C9UZL5	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.864
A0A251JG04	A0A2C9VU83	A0A251JG04	A0A2C9VU83	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.969
A0A251JLM6	A0A2C9TZF7	A0A251JLM6	A0A2C9TZF7	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.855
A0A251JLM6	A0A2C9UYK0	A0A251JLM6	A0A2C9UYK0	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.855
A0A251JLM6	A0A2C9UZL5	A0A251JLM6	A0A2C9UZL5	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.864
A0A251JLM6	A0A2C9VU83	A0A251JLM6	A0A2C9VU83	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.969
A0A251JNV0	A0A2C9UFY8	A0A251JNV0	A0A2C9UFY8	RuvB-like helicase; Belongs to the RuvB family.	Uncharacterized protein.	0.973
A0A251JNV0	A0A2C9UQK4	A0A251JNV0	A0A2C9UQK4	RuvB-like helicase; Belongs to the RuvB family.	RuvB-like helicase; Belongs to the RuvB family.	0.543
A0A251JNV0	A0A2C9VMV9	A0A251JNV0	A0A2C9VMV9	RuvB-like helicase; Belongs to the RuvB family.	DNA helicase; Belongs to the MCM family.	0.533
A0A251JNV0	A0A2C9VZN6	A0A251JNV0	A0A2C9VZN6	RuvB-like helicase; Belongs to the RuvB family.	RuvB-like helicase; Belongs to the RuvB family.	0.999
A0A251JNV0	A0A2C9WCA0	A0A251JNV0	A0A2C9WCA0	RuvB-like helicase; Belongs to the RuvB family.	Uncharacterized protein.	0.454
A0A251JNV0	A0A2C9WCA9	A0A251JNV0	A0A2C9WCA9	RuvB-like helicase; Belongs to the RuvB family.	Uncharacterized protein.	0.454
A0A251JNV0	A0A2C9WKJ9	A0A251JNV0	A0A2C9WKJ9	RuvB-like helicase; Belongs to the RuvB family.	Uncharacterized protein.	0.454
A0A251JNV0	A0A2C9WKY3	A0A251JNV0	A0A2C9WKY3	RuvB-like helicase; Belongs to the RuvB family.	Uncharacterized protein.	0.454