(66 nodes) Mitotic cell cycle phase transition network (Manihot esculenta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MANES_S050700	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (374 aa)
	A0A2C9VFI5	Serine/threonine-protein phosphatase. (313 aa)
	A0A2C9VFE9	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (328 aa)
	A0A2C9VF45	Uncharacterized protein. (494 aa)
	A0A2C9VDV6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (456 aa)
	A0A2C9VCD9	Uncharacterized protein; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family. (356 aa)
	A0A2C9VBH8	CYCLIN domain-containing protein; Belongs to the cyclin family. (336 aa)
	A0A2C9VA46	Uncharacterized protein. (246 aa)
	A0A2C9V875	Uncharacterized protein. (501 aa)
	A0A2C9V7S1	Serine/threonine-protein phosphatase. (313 aa)
	A0A2C9V4I6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (359 aa)
	A0A2C9V489	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (414 aa)
	A0A2C9V365	Uncharacterized protein. (70 aa)
	A0A2C9UWX8	Uncharacterized protein; Belongs to the cyclin family. (367 aa)
	A0A2C9UWE4	Uncharacterized protein. (1258 aa)
	A0A2C9UW39	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (356 aa)
	A0A2C9UVM7	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (304 aa)
	A0A2C9UV99	Uncharacterized protein; Belongs to the cyclin family. (340 aa)
	A0A2C9UR85	Uncharacterized protein; Belongs to the cyclin family. (394 aa)
	A0A2C9UQV2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (337 aa)
	A0A2C9UKK5	TPR_REGION domain-containing protein. (577 aa)
	A0A2C9UGA8	Uncharacterized protein. (88 aa)
	A0A2C9UEC7	TPR_REGION domain-containing protein. (544 aa)
	A0A2C9UC83	Uncharacterized protein. (596 aa)
	A0A2C9UAW3	Uncharacterized protein. (756 aa)
	A0A2C9U720	Uncharacterized protein; Belongs to the cyclin family. (598 aa)
	A0A2C9U5P4	Uncharacterized protein. (91 aa)
	A0A2C9U4N4	Uncharacterized protein; Belongs to the cyclin family. (299 aa)
	A0A2C9U3T5	Protein kinase domain-containing protein. (147 aa)
	A0A2C9U202	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (373 aa)
	A0A2C9U112	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (355 aa)
	A0A2C9U0J5	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (367 aa)
	A0A2C9U081	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (328 aa)
	A0A2C9TZG4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (431 aa)
	A0A2C9TZD1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (312 aa)
	A0A251LXN4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
	A0A251LI39	Uncharacterized protein. (494 aa)
	A0A251L7L2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (489 aa)
	A0A251L4J8	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (487 aa)
	A0A251KJL1	APC1_C domain-containing protein. (1825 aa)
	A0A251J5J9	Serine/threonine-protein phosphatase. (313 aa)
	A0A251IYZ6	Uncharacterized protein; Belongs to the cyclin family. (743 aa)
	A0A251IRA9	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (499 aa)
	MANES_S038900	Uncharacterized protein; Belongs to the cyclin family. (342 aa)
	A0A2C9VGX0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (316 aa)
	A0A2C9WMV2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
	A0A2C9WME0	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (331 aa)
	A0A2C9WMC2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (433 aa)
	A0A2C9WKI2	Uncharacterized protein. (504 aa)
	A0A2C9WHG2	CULLIN_2 domain-containing protein; Belongs to the cullin family. (880 aa)
	A0A2C9WH73	BRCT domain-containing protein; Belongs to the cyclin family. (499 aa)
	A0A2C9WFX6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (409 aa)
	A0A2C9WFF8	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (354 aa)
	A0A2C9WEG2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (413 aa)
	A0A2C9WDP4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
	A0A2C9W892	Serine/threonine-protein phosphatase. (313 aa)
	A0A2C9W5C9	Uncharacterized protein. (760 aa)
	A0A2C9VYB5	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (429 aa)
	A0A2C9VXZ8	Uncharacterized protein. (580 aa)
	A0A2C9VXY6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (312 aa)
	A0A2C9VXE9	Uncharacterized protein; Belongs to the cyclin family. (301 aa)
	A0A2C9VXC7	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (364 aa)
	A0A2C9VXA3	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (367 aa)
	A0A2C9VX25	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (330 aa)
	A0A2C9VL02	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (374 aa)
	A0A2C9VK51	Uncharacterized protein. (71 aa)

Your Current Organism:

Manihot esculenta

NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A251IRA9	A0A251IYZ6	A0A251IRA9	A0A251IYZ6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein; Belongs to the cyclin family.	0.584
A0A251IRA9	A0A251KJL1	A0A251IRA9	A0A251KJL1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	APC1_C domain-containing protein.	0.803
A0A251IRA9	A0A251LI39	A0A251IRA9	A0A251LI39	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.530
A0A251IRA9	A0A251LXN4	A0A251IRA9	A0A251LXN4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.757
A0A251IRA9	A0A2C9TZD1	A0A251IRA9	A0A2C9TZD1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.807
A0A251IRA9	A0A2C9TZG4	A0A251IRA9	A0A2C9TZG4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.583
A0A251IRA9	A0A2C9U3T5	A0A251IRA9	A0A2C9U3T5	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Protein kinase domain-containing protein.	0.807
A0A251IRA9	A0A2C9U720	A0A251IRA9	A0A2C9U720	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein; Belongs to the cyclin family.	0.530
A0A251IRA9	A0A2C9UAW3	A0A251IRA9	A0A2C9UAW3	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.607
A0A251IRA9	A0A2C9UC83	A0A251IRA9	A0A2C9UC83	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.701
A0A251IRA9	A0A2C9UEC7	A0A251IRA9	A0A2C9UEC7	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	TPR_REGION domain-containing protein.	0.736
A0A251IRA9	A0A2C9UKK5	A0A251IRA9	A0A2C9UKK5	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	TPR_REGION domain-containing protein.	0.545
A0A251IRA9	A0A2C9V875	A0A251IRA9	A0A2C9V875	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.530
A0A251IRA9	A0A2C9VA46	A0A251IRA9	A0A2C9VA46	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.542
A0A251IRA9	A0A2C9VCD9	A0A251IRA9	A0A2C9VCD9	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family.	0.542
A0A251IRA9	A0A2C9VDV6	A0A251IRA9	A0A2C9VDV6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.593
A0A251IRA9	A0A2C9VF45	A0A251IRA9	A0A2C9VF45	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.530
A0A251IRA9	A0A2C9VFE9	A0A251IRA9	A0A2C9VFE9	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.575
A0A251IRA9	A0A2C9VGX0	A0A251IRA9	A0A2C9VGX0	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.848
A0A251IRA9	A0A2C9VXY6	A0A251IRA9	A0A2C9VXY6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.807