(44 nodes) Negative regulation of cell cycle phase transition network (Manihot esculenta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A251JJM4	Uncharacterized protein. (524 aa)
	A0A251JT29	Checkpoint protein; Belongs to the HUS1 family. (320 aa)
	A0A251KDB2	Uncharacterized protein; Belongs to the rad9 family. (447 aa)
	A0A251KP80	PWWP domain-containing protein. (1099 aa)
	A0A251KX92	BUB1 N-terminal domain-containing protein. (385 aa)
	A0A251LIV9	Uncharacterized protein. (992 aa)
	A0A251LNP3	Uncharacterized protein. (886 aa)
	A0A2C9U294	Protein kinase domain-containing protein. (750 aa)
	A0A2C9UAK6	Uncharacterized protein. (884 aa)
	A0A2C9UHQ4	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (854 aa)
	A0A2C9UJM1	PWWP domain-containing protein. (1102 aa)
	A0A2C9UKB8	NAC domain-containing protein. (429 aa)
	A0A2C9UMY8	HORMA domain-containing protein. (211 aa)
	A0A2C9US12	Uncharacterized protein. (89 aa)
	A0A2C9USM0	WD_REPEATS_REGION domain-containing protein. (388 aa)
	A0A2C9USP7	HORMA domain-containing protein. (207 aa)
	A0A2C9UTY2	Uncharacterized protein. (759 aa)
	A0A2C9UU91	CDT1 domain-containing protein. (617 aa)
	A0A2C9UZB9	RB_A domain-containing protein. (646 aa)
	A0A2C9V224	BUB1 N-terminal domain-containing protein. (566 aa)
	A0A2C9V543	Uncharacterized protein. (722 aa)
	A0A2C9V557	Uncharacterized protein. (443 aa)
	A0A2C9V593	CCHC-type domain-containing protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (274 aa)
	A0A2C9V6D3	WD_REPEATS_REGION domain-containing protein. (342 aa)
	A0A2C9VA56	Uncharacterized protein. (596 aa)
	A0A2C9VJF8	Uncharacterized protein. (283 aa)
	A0A2C9VNM8	NAC domain-containing protein. (456 aa)
	A0A2C9VR47	Uncharacterized protein. (1272 aa)
	A0A2C9VSP9	Uncharacterized protein. (1001 aa)
	A0A2C9VW20	Protein kinase domain-containing protein. (502 aa)
	A0A2C9W2R4	CDT1 domain-containing protein. (611 aa)
	A0A2C9W354	ERCC4 domain-containing protein. (657 aa)
	A0A2C9WBN9	Uncharacterized protein. (193 aa)
	A0A2C9WE98	Uncharacterized protein. (303 aa)
	A0A2C9WEG8	ATPase_AAA_core domain-containing protein. (1256 aa)
	A0A2C9WEQ0	Uncharacterized protein. (947 aa)
	A0A2C9WF78	Uncharacterized protein. (243 aa)
	A0A2C9WGR2	Protein kinase domain-containing protein. (846 aa)
	A0A2C9WJN7	WD_REPEATS_REGION domain-containing protein. (314 aa)
	A0A2C9WJW7	Uncharacterized protein. (193 aa)
	A0A2C9WKB7	Uncharacterized protein. (538 aa)
	A0A2C9WL64	Cell division control protein; Belongs to the CDC6/cdc18 family. (527 aa)
	A0A2C9WN82	Uncharacterized protein. (612 aa)
	A0A2C9WQA5	Protein kinase domain-containing protein. (499 aa)

Your Current Organism:

Manihot esculenta

NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A251JJM4	A0A251JT29	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.508
A0A251JJM4	A0A2C9U294	Uncharacterized protein.	Protein kinase domain-containing protein.	0.836
A0A251JJM4	A0A2C9UHQ4	Uncharacterized protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.529
A0A251JJM4	A0A2C9UMY8	Uncharacterized protein.	HORMA domain-containing protein.	0.972
A0A251JJM4	A0A2C9USM0	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.524
A0A251JJM4	A0A2C9USP7	Uncharacterized protein.	HORMA domain-containing protein.	0.972
A0A251JJM4	A0A2C9UTY2	Uncharacterized protein.	Uncharacterized protein.	0.744
A0A251JJM4	A0A2C9V543	Uncharacterized protein.	Uncharacterized protein.	0.914
A0A251JJM4	A0A2C9V557	Uncharacterized protein.	Uncharacterized protein.	0.914
A0A251JJM4	A0A2C9V6D3	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.945
A0A251JJM4	A0A2C9WGR2	Uncharacterized protein.	Protein kinase domain-containing protein.	0.836
A0A251JJM4	A0A2C9WJN7	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.945
A0A251JJM4	A0A2C9WL64	Uncharacterized protein.	Cell division control protein; Belongs to the CDC6/cdc18 family.	0.566
A0A251JT29	A0A251JJM4	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.508
A0A251JT29	A0A251KDB2	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein; Belongs to the rad9 family.	0.992
A0A251JT29	A0A251KP80	Checkpoint protein; Belongs to the HUS1 family.	PWWP domain-containing protein.	0.790
A0A251JT29	A0A251KX92	Checkpoint protein; Belongs to the HUS1 family.	BUB1 N-terminal domain-containing protein.	0.533
A0A251JT29	A0A2C9U294	Checkpoint protein; Belongs to the HUS1 family.	Protein kinase domain-containing protein.	0.416
A0A251JT29	A0A2C9UJM1	Checkpoint protein; Belongs to the HUS1 family.	PWWP domain-containing protein.	0.790
A0A251JT29	A0A2C9UMY8	Checkpoint protein; Belongs to the HUS1 family.	HORMA domain-containing protein.	0.454