(56 nodes) Regulation of mitotic cell cycle phase transition network (Manihot esculenta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2C9UTY2	Uncharacterized protein. (759 aa)
	A0A2C9USP7	HORMA domain-containing protein. (207 aa)
	A0A2C9US12	Uncharacterized protein. (89 aa)
	A0A2C9UMY8	HORMA domain-containing protein. (211 aa)
	A0A2C9UKK5	TPR_REGION domain-containing protein. (577 aa)
	A0A2C9UJA1	Uncharacterized protein. (99 aa)
	A0A2C9UIL0	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (180 aa)
	A0A2C9UHQ4	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (854 aa)
	A0A2C9UEH2	WD_REPEATS_REGION domain-containing protein. (772 aa)
	A0A2C9UEC7	TPR_REGION domain-containing protein. (544 aa)
	A0A251J6L9	PCI domain-containing protein. (424 aa)
	A0A251JJM4	Uncharacterized protein. (524 aa)
	A0A251JT29	Checkpoint protein; Belongs to the HUS1 family. (320 aa)
	A0A251K9C5	RING-type domain-containing protein. (72 aa)
	A0A251KX92	BUB1 N-terminal domain-containing protein. (385 aa)
	A0A251LIV9	Uncharacterized protein. (992 aa)
	A0A251LNP3	Uncharacterized protein. (886 aa)
	A0A251LWG0	E3 ubiquitin protein ligase. (876 aa)
	A0A251LXN4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
	A0A2C9TZD1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (312 aa)
	A0A2C9U0A7	PCI domain-containing protein. (397 aa)
	A0A2C9UC83	Uncharacterized protein. (596 aa)
	A0A2C9U294	Protein kinase domain-containing protein. (750 aa)
	A0A2C9U3T5	Protein kinase domain-containing protein. (147 aa)
	A0A2C9U6P2	PCI domain-containing protein. (424 aa)
	A0A2C9UAK6	Uncharacterized protein. (884 aa)
	A0A2C9UAW3	Uncharacterized protein. (756 aa)
	A0A2C9WN82	Uncharacterized protein. (612 aa)
	A0A2C9WMV2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
	A0A2C9WL64	Cell division control protein; Belongs to the CDC6/cdc18 family. (527 aa)
	A0A2C9WKB7	Uncharacterized protein. (538 aa)
	A0A2C9WK60	ANAPC5 domain-containing protein. (914 aa)
	A0A2C9WJW7	Uncharacterized protein. (193 aa)
	A0A2C9WJN7	WD_REPEATS_REGION domain-containing protein. (314 aa)
	A0A2C9WGR2	Protein kinase domain-containing protein. (846 aa)
	A0A2C9WF78	Uncharacterized protein. (243 aa)
	A0A2C9WEQ0	Uncharacterized protein. (947 aa)
	A0A2C9WEG8	ATPase_AAA_core domain-containing protein. (1256 aa)
	A0A2C9WDP4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
	A0A2C9WBN9	Uncharacterized protein. (193 aa)
	A0A2C9W5C9	Uncharacterized protein. (760 aa)
	A0A2C9VY67	PCI domain-containing protein. (397 aa)
	A0A2C9VXY6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (312 aa)
	A0A2C9VTS6	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (180 aa)
	A0A2C9VTH6	E3 ubiquitin protein ligase. (892 aa)
	A0A2C9VSP9	Uncharacterized protein. (1001 aa)
	A0A2C9VMM7	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (189 aa)
	A0A2C9VJF8	Uncharacterized protein. (283 aa)
	A0A2C9VGX0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (316 aa)
	A0A2C9VF79	RING-type domain-containing protein. (57 aa)
	A0A2C9V6D3	WD_REPEATS_REGION domain-containing protein. (342 aa)
	A0A2C9V598	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (187 aa)
	A0A2C9V557	Uncharacterized protein. (443 aa)
	A0A2C9V543	Uncharacterized protein. (722 aa)
	A0A2C9V224	BUB1 N-terminal domain-containing protein. (566 aa)
	A0A2C9UZB9	RB_A domain-containing protein. (646 aa)

Your Current Organism:

Manihot esculenta

NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A251J6L9	A0A2C9U0A7	PCI domain-containing protein.	PCI domain-containing protein.	0.995
A0A251J6L9	A0A2C9U6P2	PCI domain-containing protein.	PCI domain-containing protein.	0.544
A0A251J6L9	A0A2C9VY67	PCI domain-containing protein.	PCI domain-containing protein.	0.995
A0A251JJM4	A0A251JT29	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.508
A0A251JJM4	A0A251K9C5	Uncharacterized protein.	RING-type domain-containing protein.	0.888
A0A251JJM4	A0A251LXN4	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.526
A0A251JJM4	A0A2C9TZD1	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.526
A0A251JJM4	A0A2C9U294	Uncharacterized protein.	Protein kinase domain-containing protein.	0.836
A0A251JJM4	A0A2C9U3T5	Uncharacterized protein.	Protein kinase domain-containing protein.	0.526
A0A251JJM4	A0A2C9UAW3	Uncharacterized protein.	Uncharacterized protein.	0.863
A0A251JJM4	A0A2C9UC83	Uncharacterized protein.	Uncharacterized protein.	0.916
A0A251JJM4	A0A2C9UEC7	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.970
A0A251JJM4	A0A2C9UEH2	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.958
A0A251JJM4	A0A2C9UHQ4	Uncharacterized protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.529
A0A251JJM4	A0A2C9UIL0	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.748
A0A251JJM4	A0A2C9UKK5	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.894
A0A251JJM4	A0A2C9UMY8	Uncharacterized protein.	HORMA domain-containing protein.	0.972
A0A251JJM4	A0A2C9USP7	Uncharacterized protein.	HORMA domain-containing protein.	0.972
A0A251JJM4	A0A2C9UTY2	Uncharacterized protein.	Uncharacterized protein.	0.744
A0A251JJM4	A0A2C9V543	Uncharacterized protein.	Uncharacterized protein.	0.914