(84 nodes) Telomere Maintenance network (Manihot esculenta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2C9UQK4	RuvB-like helicase; Belongs to the RuvB family. (467 aa)
	A0A0M3R849	NAC transcription factors 3. (581 aa)
	A0A0M4G3S7	NAC transcription factors 94. (292 aa)
	A0A0M5JKF0	NAC transcription factors 92. (383 aa)
	MANES_S091500	Uncharacterized protein. (226 aa)
	MANES_S029800	Uncharacterized protein. (99 aa)
	MANES_S029600	Uncharacterized protein. (112 aa)
	MANES_S022500	Histone H2B; Belongs to the histone H2B family. (139 aa)
	MANES_S011500	ATP-dependent DNA helicase; Belongs to the helicase family. (166 aa)
	A0A251JF57	Uncharacterized protein. (1170 aa)
	A0A251JNV0	RuvB-like helicase; Belongs to the RuvB family. (467 aa)
	A0A251K0S2	Uncharacterized protein. (1230 aa)
	A0A251K6R8	Uncharacterized protein. (1494 aa)
	A0A251K809	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (614 aa)
	A0A251KRR0	NAC domain-containing protein. (373 aa)
	A0A251KTJ3	Uncharacterized protein. (391 aa)
	A0A251LAJ3	3'-5' exonuclease domain-containing protein. (319 aa)
	A0A2C9U2V9	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (888 aa)
	A0A2C9U3K4	ATP-dependent DNA helicase; Belongs to the helicase family. (331 aa)
	A0A2C9U3P5	CCHC-type domain-containing protein. (163 aa)
	A0A2C9U463	Helitron_like_N domain-containing protein. (115 aa)
	A0A2C9U592	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (849 aa)
	A0A2C9U6T5	Uncharacterized protein. (403 aa)
	A0A2C9U7G9	Uncharacterized protein. (91 aa)
	A0A2C9U8N5	Uncharacterized protein. (536 aa)
	A0A2C9UCN1	Uncharacterized protein. (210 aa)
	A0A2C9UCY1	AAA domain-containing protein. (961 aa)
	A0A2C9UHM1	Uncharacterized protein. (132 aa)
	A0A2C9UME4	PUA domain-containing protein. (615 aa)
	A0A2C9UN78	Uncharacterized protein. (439 aa)
	A0A2C9UNK8	Uncharacterized protein. (64 aa)
	A0A2C9UNL4	Uncharacterized protein. (64 aa)
	A0A2C9UNR1	NAC domain-containing protein. (623 aa)
	A0A2C9UP24	Uncharacterized protein. (891 aa)
	A0A2C9UP90	Uncharacterized protein. (263 aa)
	A0A2C9UQ53	ATP-dependent DNA helicase; Belongs to the helicase family. (355 aa)
	A0A2C9USN2	Uncharacterized protein. (264 aa)
	A0A2C9USS9	Uncharacterized protein. (1177 aa)
	A0A2C9UUV2	Uncharacterized protein. (398 aa)
	A0A2C9UV41	ATP-dependent DNA helicase; Belongs to the helicase family. (269 aa)
	A0A2C9UZ96	ATP-dependent DNA helicase; Belongs to the helicase family. (211 aa)
	A0A2C9V112	Histone H2B; Belongs to the histone H2B family. (147 aa)
	A0A2C9V1K4	Histone H2B; Belongs to the histone H2B family. (145 aa)
	A0A2C9V1K5	Histone domain-containing protein; Belongs to the histone H2B family. (233 aa)
	A0A2C9V2H4	3'-5' exonuclease domain-containing protein. (249 aa)
	A0A2C9V3L1	Histone H2B; Belongs to the histone H2B family. (139 aa)
	A0A2C9V464	Helitron_like_N domain-containing protein. (355 aa)
	A0A2C9V4V6	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1335 aa)
	A0A2C9V5J4	ATP-dependent DNA helicase; Belongs to the helicase family. (136 aa)
	A0A2C9V6M6	Uncharacterized protein. (134 aa)
	A0A2C9VA78	NAC domain-containing protein. (245 aa)
	A0A2C9VAA3	NAC domain-containing protein. (185 aa)
	A0A2C9VAQ5	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (190 aa)
	A0A2C9VBM3	Uncharacterized protein. (127 aa)
	A0A2C9VDY7	NAC domain-containing protein. (254 aa)
	A0A2C9VEH9	Uncharacterized protein. (220 aa)
	A0A2C9VFJ8	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (879 aa)
	A0A2C9VG76	Uncharacterized protein. (294 aa)
	A0A2C9VGT0	3'-5' exonuclease domain-containing protein. (256 aa)
	A0A2C9VGT5	3'-5' exonuclease domain-containing protein. (223 aa)
	A0A2C9VH00	Uncharacterized protein. (556 aa)
	A0A2C9VHW2	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (196 aa)
	A0A2C9VJU8	Histone H2B; Belongs to the histone H2B family. (140 aa)
	A0A2C9VM10	PUA domain-containing protein. (616 aa)
	A0A2C9VM95	Histone H2B; Belongs to the histone H2B family. (139 aa)
	A0A2C9VNN1	Uncharacterized protein. (354 aa)
	A0A2C9VP72	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (624 aa)
	A0A2C9VS54	Uncharacterized protein. (238 aa)
	A0A2C9VTA2	Uncharacterized protein. (125 aa)
	A0A2C9VU82	NAC domain-containing protein. (494 aa)
	A0A2C9VXJ6	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (157 aa)
	A0A2C9VYS0	Uncharacterized protein. (370 aa)
	A0A2C9VZZ5	Histone H2B; Belongs to the histone H2B family. (143 aa)
	A0A2C9W010	HD domain-containing protein. (223 aa)
	A0A2C9W0H3	Histone H2B; Belongs to the histone H2B family. (147 aa)
	A0A2C9W6U2	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (668 aa)
	A0A2C9W712	ATP-dependent DNA helicase; Belongs to the helicase family. (125 aa)
	A0A2C9W997	Uncharacterized protein. (208 aa)
	A0A2C9WC44	ATP-dependent DNA helicase; Belongs to the helicase family. (510 aa)
	A0A2C9WGZ3	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (157 aa)
	A0A2C9WL27	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (724 aa)
	A0A2C9WNK7	NAC domain-containing protein. (516 aa)
	A0A2C9WPW4	NAC domain-containing protein. (513 aa)
	A0A2C9WR64	NAC domain-containing protein. (68 aa)

Your Current Organism:

Manihot esculenta

NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0M3R849	A0A251JF57	A0A0M3R849	A0A251JF57	NAC transcription factors 3.	Uncharacterized protein.	0.466
A0A0M3R849	A0A251K0S2	A0A0M3R849	A0A251K0S2	NAC transcription factors 3.	Uncharacterized protein.	0.466
A0A0M3R849	A0A251K809	A0A0M3R849	A0A251K809	NAC transcription factors 3.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.466
A0A0M3R849	A0A2C9U2V9	A0A0M3R849	A0A2C9U2V9	NAC transcription factors 3.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.954
A0A0M3R849	A0A2C9UP24	A0A0M3R849	A0A2C9UP24	NAC transcription factors 3.	Uncharacterized protein.	0.466
A0A0M3R849	A0A2C9USS9	A0A0M3R849	A0A2C9USS9	NAC transcription factors 3.	Uncharacterized protein.	0.466
A0A0M3R849	A0A2C9V4V6	A0A0M3R849	A0A2C9V4V6	NAC transcription factors 3.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.613
A0A0M3R849	A0A2C9VFJ8	A0A0M3R849	A0A2C9VFJ8	NAC transcription factors 3.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.466
A0A0M3R849	A0A2C9WL27	A0A0M3R849	A0A2C9WL27	NAC transcription factors 3.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.466
A0A0M4G3S7	A0A251JF57	A0A0M4G3S7	A0A251JF57	NAC transcription factors 94.	Uncharacterized protein.	0.466
A0A0M4G3S7	A0A251K0S2	A0A0M4G3S7	A0A251K0S2	NAC transcription factors 94.	Uncharacterized protein.	0.466
A0A0M4G3S7	A0A251K809	A0A0M4G3S7	A0A251K809	NAC transcription factors 94.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.466
A0A0M4G3S7	A0A2C9U2V9	A0A0M4G3S7	A0A2C9U2V9	NAC transcription factors 94.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.954
A0A0M4G3S7	A0A2C9UP24	A0A0M4G3S7	A0A2C9UP24	NAC transcription factors 94.	Uncharacterized protein.	0.466
A0A0M4G3S7	A0A2C9USS9	A0A0M4G3S7	A0A2C9USS9	NAC transcription factors 94.	Uncharacterized protein.	0.466
A0A0M4G3S7	A0A2C9V4V6	A0A0M4G3S7	A0A2C9V4V6	NAC transcription factors 94.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.613
A0A0M4G3S7	A0A2C9VFJ8	A0A0M4G3S7	A0A2C9VFJ8	NAC transcription factors 94.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.466
A0A0M4G3S7	A0A2C9WL27	A0A0M4G3S7	A0A2C9WL27	NAC transcription factors 94.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.466
A0A0M5JKF0	A0A251JF57	A0A0M5JKF0	A0A251JF57	NAC transcription factors 92.	Uncharacterized protein.	0.466
A0A0M5JKF0	A0A251K0S2	A0A0M5JKF0	A0A251K0S2	NAC transcription factors 92.	Uncharacterized protein.	0.466