(11 nodes) p75 NTR receptor-mediated signalling network (Manihot esculenta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2C9VGG5	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (450 aa)
	A0A2C9VC94	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (455 aa)
	A0A2C9VF52	Ubiquitin-like domain-containing protein. (33 aa)
	A0A2C9WNI8	Ubiquitin-like domain-containing protein. (156 aa)
	A0A2C9WQZ0	Uncharacterized protein. (414 aa)
	A0A2C9UND2	Ubiquitin-like domain-containing protein. (156 aa)
	A0A2C9UT49	Ubiquitin-like domain-containing protein. (156 aa)
	A0A2C9WBZ8	Ncstrn_small domain-containing protein. (671 aa)
	A0A2C9W621	Uncharacterized protein. (76 aa)
	A0A2C9VSB5	Ubiquitin-like domain-containing protein. (156 aa)
	A0A2C9VP23	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (426 aa)

Your Current Organism:

Manihot esculenta

NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2C9UND2	A0A2C9WQZ0	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.527
A0A2C9UT49	A0A2C9WQZ0	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.527
A0A2C9VC94	A0A2C9WBZ8	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Ncstrn_small domain-containing protein.	0.983
A0A2C9VF52	A0A2C9WQZ0	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.527
A0A2C9VGG5	A0A2C9WBZ8	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Ncstrn_small domain-containing protein.	0.983
A0A2C9VP23	A0A2C9WBZ8	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Ncstrn_small domain-containing protein.	0.984
A0A2C9VSB5	A0A2C9WQZ0	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.527
A0A2C9W621	A0A2C9WBZ8	Uncharacterized protein.	Ncstrn_small domain-containing protein.	0.976
A0A2C9WBZ8	A0A2C9VC94	Ncstrn_small domain-containing protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.983
A0A2C9WBZ8	A0A2C9VGG5	Ncstrn_small domain-containing protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.983
A0A2C9WBZ8	A0A2C9VP23	Ncstrn_small domain-containing protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.984
A0A2C9WBZ8	A0A2C9W621	Ncstrn_small domain-containing protein.	Uncharacterized protein.	0.976
A0A2C9WNI8	A0A2C9WQZ0	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.527
A0A2C9WQZ0	A0A2C9UND2	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.527
A0A2C9WQZ0	A0A2C9UT49	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.527
A0A2C9WQZ0	A0A2C9VF52	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.527
A0A2C9WQZ0	A0A2C9VSB5	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.527
A0A2C9WQZ0	A0A2C9WNI8	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.527