(16 nodes) Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA network (Manihot esculenta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2C9WKX2	RNase_PH domain-containing protein. (242 aa)
	A0A2C9WMA9	Uncharacterized protein. (460 aa)
	A0A2C9VLN6	Nudix hydrolase domain-containing protein. (324 aa)
	A0A251KAJ6	RNase_PH domain-containing protein. (303 aa)
	A0A251LVM0	Uncharacterized protein. (241 aa)
	A0A2C9U5H2	S1 domain-containing protein. (321 aa)
	A0A2C9UJF5	KH_dom_type_1 domain-containing protein. (151 aa)
	A0A2C9V1X5	Importin N-terminal domain-containing protein. (893 aa)
	A0A2C9VAX0	Bulb-type lectin domain-containing protein. (409 aa)
	A0A2C9VG96	Uncharacterized protein. (210 aa)
	A0A2C9VQF6	Uncharacterized protein. (318 aa)
	A0A2C9VW54	Importin N-terminal domain-containing protein. (890 aa)
	A0A2C9VXI6	Uncharacterized protein. (316 aa)
	A0A2C9W043	Uncharacterized protein. (256 aa)
	A0A2C9W669	Uncharacterized protein. (287 aa)
	A0A2C9WE60	Uncharacterized protein. (459 aa)

Your Current Organism:

Manihot esculenta

NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A251KAJ6	A0A251LVM0	RNase_PH domain-containing protein.	Uncharacterized protein.	0.998
A0A251KAJ6	A0A2C9U5H2	RNase_PH domain-containing protein.	S1 domain-containing protein.	0.998
A0A251KAJ6	A0A2C9UJF5	RNase_PH domain-containing protein.	KH_dom_type_1 domain-containing protein.	0.998
A0A251KAJ6	A0A2C9V1X5	RNase_PH domain-containing protein.	Importin N-terminal domain-containing protein.	0.713
A0A251KAJ6	A0A2C9VAX0	RNase_PH domain-containing protein.	Bulb-type lectin domain-containing protein.	0.993
A0A251KAJ6	A0A2C9VG96	RNase_PH domain-containing protein.	Uncharacterized protein.	0.997
A0A251KAJ6	A0A2C9VLN6	RNase_PH domain-containing protein.	Nudix hydrolase domain-containing protein.	0.793
A0A251KAJ6	A0A2C9VQF6	RNase_PH domain-containing protein.	Uncharacterized protein.	0.770
A0A251KAJ6	A0A2C9VW54	RNase_PH domain-containing protein.	Importin N-terminal domain-containing protein.	0.713
A0A251KAJ6	A0A2C9VXI6	RNase_PH domain-containing protein.	Uncharacterized protein.	0.770
A0A251KAJ6	A0A2C9W043	RNase_PH domain-containing protein.	Uncharacterized protein.	0.997
A0A251KAJ6	A0A2C9W669	RNase_PH domain-containing protein.	Uncharacterized protein.	0.998
A0A251KAJ6	A0A2C9WE60	RNase_PH domain-containing protein.	Uncharacterized protein.	0.997
A0A251KAJ6	A0A2C9WKX2	RNase_PH domain-containing protein.	RNase_PH domain-containing protein.	0.998
A0A251KAJ6	A0A2C9WMA9	RNase_PH domain-containing protein.	Uncharacterized protein.	0.997
A0A251LVM0	A0A251KAJ6	Uncharacterized protein.	RNase_PH domain-containing protein.	0.998
A0A251LVM0	A0A2C9U5H2	Uncharacterized protein.	S1 domain-containing protein.	0.998
A0A251LVM0	A0A2C9UJF5	Uncharacterized protein.	KH_dom_type_1 domain-containing protein.	0.997
A0A251LVM0	A0A2C9V1X5	Uncharacterized protein.	Importin N-terminal domain-containing protein.	0.663
A0A251LVM0	A0A2C9VAX0	Uncharacterized protein.	Bulb-type lectin domain-containing protein.	0.988