(23 nodes) Base-Excision Repair, AP Site Formation network (Manihot esculenta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	MANES_S022500	Histone H2B; Belongs to the histone H2B family. (139 aa)
	A0A2C9WBK4	CMP/dCMP-type deaminase domain-containing protein. (153 aa)
	A0A2C9W5P7	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (312 aa)
	A0A2C9W0H3	Histone H2B; Belongs to the histone H2B family. (147 aa)
	A0A2C9VZZ5	Histone H2B; Belongs to the histone H2B family. (143 aa)
	NTH1	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (362 aa)
	A0A2C9VVE7	CMP/dCMP-type deaminase domain-containing protein. (435 aa)
	A0A2C9VR50	CMP/dCMP-type deaminase domain-containing protein. (1373 aa)
	A0A2C9VM95	Histone H2B; Belongs to the histone H2B family. (139 aa)
	A0A2C9VLX3	Uncharacterized protein. (478 aa)
	A0A2C9VJU8	Histone H2B; Belongs to the histone H2B family. (140 aa)
	A0A2C9VFW2	CMP/dCMP-type deaminase domain-containing protein. (186 aa)
	A0A2C9V3L1	Histone H2B; Belongs to the histone H2B family. (139 aa)
	A0A2C9VB35	CMP/dCMP-type deaminase domain-containing protein. (186 aa)
	A0A251LJ82	ENDO3c domain-containing protein. (412 aa)
	A0A2C9U352	Uncharacterized protein. (395 aa)
	A0A2C9VDC3	Uncharacterized protein. (268 aa)
	A0A2C9U3H1	Uncharacterized protein. (397 aa)
	A0A2C9UPD1	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (465 aa)
	A0A2C9US28	CMP/dCMP-type deaminase domain-containing protein. (591 aa)
	A0A2C9V112	Histone H2B; Belongs to the histone H2B family. (147 aa)
	A0A2C9V1K4	Histone H2B; Belongs to the histone H2B family. (145 aa)
	A0A2C9V1K5	Histone domain-containing protein; Belongs to the histone H2B family. (233 aa)

Your Current Organism:

Manihot esculenta

NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A251LJ82	A0A2C9UPD1	A0A251LJ82	A0A2C9UPD1	ENDO3c domain-containing protein.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.595
A0A251LJ82	A0A2C9VDC3	A0A251LJ82	A0A2C9VDC3	ENDO3c domain-containing protein.	Uncharacterized protein.	0.412
A0A251LJ82	A0A2C9W5P7	A0A251LJ82	A0A2C9W5P7	ENDO3c domain-containing protein.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.531
A0A251LJ82	NTH1	A0A251LJ82	A0A2C9VZH5	ENDO3c domain-containing protein.	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.587
A0A2C9U352	A0A2C9UPD1	A0A2C9U352	A0A2C9UPD1	Uncharacterized protein.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.528
A0A2C9U352	A0A2C9VDC3	A0A2C9U352	A0A2C9VDC3	Uncharacterized protein.	Uncharacterized protein.	0.412
A0A2C9U352	A0A2C9W5P7	A0A2C9U352	A0A2C9W5P7	Uncharacterized protein.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.531
A0A2C9U352	NTH1	A0A2C9U352	A0A2C9VZH5	Uncharacterized protein.	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.569
A0A2C9U3H1	A0A2C9UPD1	A0A2C9U3H1	A0A2C9UPD1	Uncharacterized protein.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.528
A0A2C9U3H1	A0A2C9VDC3	A0A2C9U3H1	A0A2C9VDC3	Uncharacterized protein.	Uncharacterized protein.	0.412
A0A2C9U3H1	A0A2C9W5P7	A0A2C9U3H1	A0A2C9W5P7	Uncharacterized protein.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.531
A0A2C9U3H1	NTH1	A0A2C9U3H1	A0A2C9VZH5	Uncharacterized protein.	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.569
A0A2C9UPD1	A0A251LJ82	A0A2C9UPD1	A0A251LJ82	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	ENDO3c domain-containing protein.	0.595
A0A2C9UPD1	A0A2C9U352	A0A2C9UPD1	A0A2C9U352	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	Uncharacterized protein.	0.528
A0A2C9UPD1	A0A2C9U3H1	A0A2C9UPD1	A0A2C9U3H1	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	Uncharacterized protein.	0.528
A0A2C9UPD1	A0A2C9VDC3	A0A2C9UPD1	A0A2C9VDC3	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	Uncharacterized protein.	0.565
A0A2C9UPD1	A0A2C9VLX3	A0A2C9UPD1	A0A2C9VLX3	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	Uncharacterized protein.	0.528
A0A2C9UPD1	A0A2C9W5P7	A0A2C9UPD1	A0A2C9W5P7	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.662
A0A2C9UPD1	NTH1	A0A2C9UPD1	A0A2C9VZH5	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.676
A0A2C9US28	A0A2C9VVE7	A0A2C9US28	A0A2C9VVE7	CMP/dCMP-type deaminase domain-containing protein.	CMP/dCMP-type deaminase domain-containing protein.	0.927