(41 nodes) Selective autophagy network (Manihot esculenta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2C9WMR0	Autophagy protein 5; Required for autophagy. (362 aa)
	A0A251JZB7	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	A0A251KP80	PWWP domain-containing protein. (1099 aa)
	A0A2C9U5W0	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (279 aa)
	A0A2C9UE04	Uncharacterized protein. (103 aa)
	A0A2C9UEK0	Uncharacterized protein. (436 aa)
	A0A2C9UEX1	TMEM189_B_dmain domain-containing protein. (306 aa)
	A0A2C9UFT6	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (449 aa)
	A0A2C9UHW3	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (279 aa)
	A0A2C9UJM1	PWWP domain-containing protein. (1102 aa)
	A0A2C9UND2	Ubiquitin-like domain-containing protein. (156 aa)
	A0A2C9UQN9	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (418 aa)
	A0A2C9UR21	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (425 aa)
	A0A2C9US16	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (982 aa)
	A0A2C9USW3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)
	A0A2C9UT49	Ubiquitin-like domain-containing protein. (156 aa)
	A0A2C9UV87	Uncharacterized protein. (106 aa)
	A0A2C9UVF4	Protein kinase domain-containing protein. (71 aa)
	A0A2C9UVJ5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (417 aa)
	A0A2C9UYS9	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Belongs to the ATG12 family. (96 aa)
	A0A2C9V4F5	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (415 aa)
	A0A2C9V5L5	Uncharacterized protein. (366 aa)
	A0A2C9VCX9	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
	A0A2C9VF52	Ubiquitin-like domain-containing protein. (33 aa)
	A0A2C9VNI3	Uncharacterized protein. (391 aa)
	A0A2C9VPP1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2526 aa)
	A0A2C9VSB5	Ubiquitin-like domain-containing protein. (156 aa)
	A0A2C9VTK6	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (286 aa)
	A0A2C9VVN8	Uncharacterized protein. (925 aa)
	A0A2C9VY63	Uncharacterized protein. (389 aa)
	A0A2C9VZK9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)
	A0A2C9W5E4	Uncharacterized protein. (375 aa)
	A0A2C9W635	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (450 aa)
	A0A2C9WAE5	Uncharacterized protein. (100 aa)
	A0A2C9WD88	Uncharacterized protein. (154 aa)
	A0A2C9WDH6	Autophagy protein 5; Required for autophagy. (355 aa)
	A0A2C9WGI8	TPR_REGION domain-containing protein. (743 aa)
	A0A2C9WK21	Uncharacterized protein. (391 aa)
	A0A2C9WNI8	Ubiquitin-like domain-containing protein. (156 aa)
	A0A2C9WMF8	Uncharacterized protein. (395 aa)
	A0A2C9WMK4	Uncharacterized protein. (394 aa)

Your Current Organism:

Manihot esculenta

NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A251KP80	A0A2C9UND2	PWWP domain-containing protein.	Ubiquitin-like domain-containing protein.	0.464
A0A251KP80	A0A2C9UT49	PWWP domain-containing protein.	Ubiquitin-like domain-containing protein.	0.464
A0A251KP80	A0A2C9VF52	PWWP domain-containing protein.	Ubiquitin-like domain-containing protein.	0.464
A0A251KP80	A0A2C9VSB5	PWWP domain-containing protein.	Ubiquitin-like domain-containing protein.	0.464
A0A251KP80	A0A2C9VY63	PWWP domain-containing protein.	Uncharacterized protein.	0.688
A0A251KP80	A0A2C9WGI8	PWWP domain-containing protein.	TPR_REGION domain-containing protein.	0.688
A0A251KP80	A0A2C9WNI8	PWWP domain-containing protein.	Ubiquitin-like domain-containing protein.	0.464
A0A2C9U5W0	A0A2C9UHW3	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.900
A0A2C9U5W0	A0A2C9UR21	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.882
A0A2C9U5W0	A0A2C9USW3	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.943
A0A2C9U5W0	A0A2C9UVF4	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Protein kinase domain-containing protein.	0.882
A0A2C9U5W0	A0A2C9UVJ5	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.943
A0A2C9U5W0	A0A2C9VTK6	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.901
A0A2C9U5W0	A0A2C9VZK9	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.943
A0A2C9UEK0	A0A2C9UND2	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.423
A0A2C9UEK0	A0A2C9UT49	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.423
A0A2C9UEK0	A0A2C9VF52	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.423
A0A2C9UEK0	A0A2C9VSB5	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.423
A0A2C9UEK0	A0A2C9WNI8	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.423
A0A2C9UEX1	A0A2C9UND2	TMEM189_B_dmain domain-containing protein.	Ubiquitin-like domain-containing protein.	0.864