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metC-2 metC-2 aspB-2 aspB-2 metB metB ADC49978.1 ADC49978.1 gabT gabT kynU kynU iscS iscS ectB ectB aspB aspB gsaB gsaB ADC50272.1 ADC50272.1 ADC50306.1 ADC50306.1 psa psa ynbB ynbB glyA glyA ADC49374.1 ADC49374.1 sufS sufS ADC49055.1 ADC49055.1 ADC48991.1 ADC48991.1 patB patB bioA bioA ADC48778.1 ADC48778.1 hemL-2 hemL-2 rocD rocD hemL hemL argD argD gcvP1 gcvP1 gcvP2 gcvP2 idcC idcC selA selA aat aat yodT yodT ADC50418.1 ADC50418.1 ADC50995.1 ADC50995.1 ADC51071.1 ADC51071.1 hisH-2 hisH-2 iscS2 iscS2 ADC51349.1 ADC51349.1 ADC51306.1 ADC51306.1 ADC51298.1 ADC51298.1 bioF bioF ADC49603.1 ADC49603.1 nifS nifS cad cad ADC49867.1 ADC49867.1 metC metC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metC-2COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (373 aa)
aspB-2COG0436 Aspartate/tyrosine/aromatic aminotransferase. (394 aa)
metBCOG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (394 aa)
ADC49978.1COG2008 Threonine aldolase. (338 aa)
gabTCOG0160 4-aminobutyrate aminotransferase and related aminotransferases. (445 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (425 aa)
iscSCOG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (387 aa)
ectBDiaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
aspBCOG0436 Aspartate/tyrosine/aromatic aminotransferase. (384 aa)
gsaBCOG0001 Glutamate-1-semialdehyde aminotransferase. (432 aa)
ADC50272.1Transaminase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (392 aa)
ADC50306.1Aminotransferase; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (400 aa)
psaPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (362 aa)
ynbBCOG4100 Cystathionine beta-lyase family protein involved in aluminum resistance. (415 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
ADC49374.1Aminotransferase family protein; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family. (376 aa)
sufSCysteine desulfurase SufS; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (406 aa)
ADC49055.1COG2873 O-acetylhomoserine sulfhydrylase. (430 aa)
ADC48991.1Hypothetical protein; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (390 aa)
patBAminotransferase; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities. (391 aa)
bioAAdenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (451 aa)
ADC48778.1L-cysteine sulfurtransferase (iron-sulfur cofactor synthesis); COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (380 aa)
hemL-2COG0001 Glutamate-1-semialdehyde aminotransferase. (428 aa)
rocDOrnithine--oxo-acid transaminase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (396 aa)
hemLCOG0001 Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)
argDCOG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (385 aa)
gcvP1Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (447 aa)
gcvP2Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (486 aa)
idcCCOG1982 Arginine/lysine/ornithine decarboxylases. (490 aa)
selASelenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (463 aa)
aatCOG0436 Aspartate/tyrosine/aromatic aminotransferase. (398 aa)
yodTAminotransferase class III; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
ADC50418.1Fe-S cluster formation protein classV; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (387 aa)
ADC50995.1Methionine gamma-lyase; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (396 aa)
ADC51071.1Aminotransferase; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (358 aa)
hisH-2COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (368 aa)
iscS2COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (371 aa)
ADC51349.1COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (470 aa)
ADC51306.1COG0076 Glutamate decarboxylase and related PLP-dependent proteins. (514 aa)
ADC51298.1Aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
bioF8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (406 aa)
ADC49603.1Hypothetical protein; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (395 aa)
nifSAminotransferase required for NAD biosynthesis (NifS protein); COG0520 Selenocysteine lyase. (382 aa)
cadCOG1982 Arginine/lysine/ornithine decarboxylases. (483 aa)
ADC49867.1Aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (451 aa)
metCCOG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (384 aa)
Your Current Organism:
Bacillus pseudofirmus
NCBI taxonomy Id: 398511
Other names: B. pseudofirmus OF4, Bacillus pseudofirmus OF4, Bacillus pseudofirmus str. OF4, Bacillus pseudofirmus strain OF4
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