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ACD14698.1 ACD14698.1 ACD14711.1 ACD14711.1 ACD14728.1 ACD14728.1 ACD14866.1 ACD14866.1 gpmA gpmA ACD15064.1 ACD15064.1 ilvA ilvA ACD15187.1 ACD15187.1 glyA glyA ACD15214.1 ACD15214.1 ectC ectC ACD15747.1 ACD15747.1 ACD16052.1 ACD16052.1 ACD16214.1 ACD16214.1 ACD16215.1 ACD16215.1 ACD16263.1 ACD16263.1 ACD16280.1 ACD16280.1 ACD16298.1 ACD16298.1 ACD16312.1 ACD16312.1 ACD16400.1 ACD16400.1 ACD16404.1 ACD16404.1 ilvA-2 ilvA-2 ACD16675.1 ACD16675.1 ACD16768.1 ACD16768.1 ACD16901.1 ACD16901.1 ACD16984.1 ACD16984.1 ACD17215.1 ACD17215.1 ACD17323.1 ACD17323.1 serC serC ACD17739.1 ACD17739.1 gcvT gcvT gcvH gcvH gcvP gcvP ACD18271.1 ACD18271.1 ACD18303.1 ACD18303.1 ACD18754.1 ACD18754.1 ACD18802.1 ACD18802.1 ACD19411.1 ACD19411.1 ACD19412.1 ACD19412.1 ACD19413.1 ACD19413.1 ACD19414.1 ACD19414.1 ACD19415.1 ACD19415.1 betA betA betB betB glyA-2 glyA-2 ACD20302.1 ACD20302.1 ACD20416.1 ACD20416.1 ACD20426.1 ACD20426.1 ACD20473.1 ACD20473.1 ACD20674.1 ACD20674.1 ACD20765.1 ACD20765.1 ACD20835.1 ACD20835.1 ACD21078.1 ACD21078.1 thrB thrB trpA trpA trpB trpB asd asd ACD21248.1 ACD21248.1 tdh tdh kbl kbl ACD21355.1 ACD21355.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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ACD14698.1Glycine hydroxymethyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; glycine hydroxymethyltransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mka:MK0122 glycine hydroxymethyltransferase. (358 aa)
ACD14711.1PFAM: FAD dependent oxidoreductase; KEGG: mgi:Mflv_1296 FAD dependent oxidoreductase. (376 aa)
ACD14728.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bxe:Bxe_A4423 putative 2-hydroxyacid dehydrogenase. (337 aa)
ACD14866.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bxe:Bxe_A4269 putative 2-hydroxyacid dehydrogenase. (313 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa)
ACD15064.1KEGG: bxe:Bxe_A4060 putative D-serine deaminase (d-serine dehydratase) protein. (425 aa)
ilvAThreonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (507 aa)
ACD15187.1PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bxe:Bxe_A3915 putative short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
ACD15214.1PFAM: aminotransferase class V; KEGG: bch:Bcen2424_0828 aminotransferase, class V. (412 aa)
ectCEctoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (137 aa)
ACD15747.1TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: bxe:Bxe_A3227 CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (288 aa)
ACD16052.1TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: bxe:Bxe_A2810 dihydrolipoamide dehydrogenase. (476 aa)
ACD16214.1PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: bxe:Bxe_A2381 homoserine dehydrogenase. (443 aa)
ACD16215.1KEGG: bxe:Bxe_A2380 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (483 aa)
ACD16263.1KEGG: bxe:Bxe_A2331 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3. (279 aa)
ACD16280.1PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bxe:Bxe_A2315 putative amino-acid dehydratase. (344 aa)
ACD16298.1PFAM: FAD dependent oxidoreductase; KEGG: bxe:Bxe_B2709 hypothetical protein. (390 aa)
ACD16312.1PFAM: glycerate kinase; KEGG: bxe:Bxe_A2298 glycerate kinase; Belongs to the glycerate kinase type-1 family. (381 aa)
ACD16400.1PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: bur:Bcep18194_B2838 glucose-methanol-choline oxidoreductase. (553 aa)
ACD16404.1PFAM: Copper amine oxidase; Copper amine oxidase N2-terminal; Copper amine oxidase N3-terminal; KEGG: bra:BRADO6525 tyramine oxidase. (661 aa)
ilvA-2Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (524 aa)
ACD16675.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bxe:Bxe_A1982 putative 2-ketogluconate 6-phosphate reductase, TkrA. (321 aa)
ACD16768.1PFAM: Rieske [2Fe-2S] domain protein; KEGG: bxe:Bxe_A3468 putative iron-sulphur Rieske protein. (387 aa)
ACD16901.1KEGG: bxe:Bxe_A1630 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (416 aa)
ACD16984.1TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: biotin/lipoyl attachment domain-containing protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: bxe:Bxe_A1543 dihydrolipoamide dehydrogenase. (600 aa)
ACD17215.1Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (343 aa)
ACD17323.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bxe:Bxe_A1055 putative 2-ketogluconate reductase. (329 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (360 aa)
ACD17739.1PFAM: Phosphoglycerate mutase; KEGG: bxe:Bxe_A0613 putative phosphoglycerate mutase. (223 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (372 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (978 aa)
ACD18271.1L-serine dehydratase 1; KEGG: bxe:Bxe_A0052 iron-sulfur-dependent L-serine dehydratase single chain form; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain. (462 aa)
ACD18303.1PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: bxe:Bxe_A0016 oxidoreductase, GMC family. (570 aa)
ACD18754.1PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: bxe:Bxe_B0698 putative glucose-methanol-choline oxidoreductase. (551 aa)
ACD18802.1PFAM: FAD dependent oxidoreductase; KEGG: bxe:Bxe_B0746 putative oxidoreductase. (375 aa)
ACD19411.1L-serine dehydratase 1; KEGG: bxe:Bxe_B1601 iron-sulfur-dependent L-serine dehydratase single chain form; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain. (464 aa)
ACD19412.1TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: bxe:Bxe_B1600 sarcosine oxidase, beta subunit, heterotetrameric. (414 aa)
ACD19413.1PFAM: Sarcosine oxidase delta subunit heterotetrameric; KEGG: bxe:Bxe_B1599 SoxD. (112 aa)
ACD19414.1TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glycine cleavage T protein (aminomethyl transferase); FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Glycine cleavage T-protein barrel; KEGG: bxe:Bxe_B1598 sarcosine oxidase, alpha subunit, heterotetrameric; Belongs to the GcvT family. (1000 aa)
ACD19415.1PFAM: Sarcosine oxidase gamma subunit; KEGG: bxe:Bxe_B1597 sarcosine oxidase, gamma subunit. (218 aa)
betACholine dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (561 aa)
betBBetaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. (489 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa)
ACD20302.1Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class-III; KEGG: bxe:Bxe_B2204 threonine aldolase. (335 aa)
ACD20416.1PFAM: FAD dependent oxidoreductase; KEGG: bxe:Bxe_B1501 FAD dependent oxidoreductase. (389 aa)
ACD20426.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bxe:Bxe_B1490 D-isomer specific 2-hydroxyacid dehydrogenase. (308 aa)
ACD20473.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: reh:H16_B0611 glycerate dehydrogenase. (321 aa)
ACD20674.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mpt:Mpe_A3260 putative 2-hydroxyacid dehydrogenase family protein. (274 aa)
ACD20765.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mlo:mlr3367 phosphoglycerate dehydrogenase. (327 aa)
ACD20835.1PFAM: FAD dependent oxidoreductase; KEGG: pol:Bpro_4345 FAD dependent oxidoreductase. (374 aa)
ACD21078.1PFAM: Rieske [2Fe-2S] domain protein; KEGG: bxe:Bxe_B2830 putative osmotic adaptation-related protein. (368 aa)
thrBKEGG: bxe:Bxe_B2840 homoserine kinase; TIGRFAM: homoserine kinase; PFAM: aminoglycoside phosphotransferase; Belongs to the pseudomonas-type ThrB family. (331 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (270 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (397 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (373 aa)
ACD21248.1Serine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: bxe:Bxe_B3001 serine--glyoxylate transaminase. (406 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (343 aa)
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (399 aa)
ACD21355.1PFAM: Aldehyde Dehydrogenase_; KEGG: bxe:Bxe_B0183 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa)
Your Current Organism:
Paraburkholderia phytofirmans
NCBI taxonomy Id: 398527
Other names: Burkholderia phytofirmans PsJN, Burkholderia sp. PsJN, P. phytofirmans PsJN, Paraburkholderia phytofirmans PsJN
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