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Daci_0169 Daci_0169 Daci_0232 Daci_0232 Daci_0278 Daci_0278 Daci_0530 Daci_0530 Daci_0953 Daci_0953 Daci_1442 Daci_1442 mdcB mdcB Daci_1764 Daci_1764 Daci_1765 Daci_1765 Daci_1766 Daci_1766 Daci_1767 Daci_1767 Daci_1768 Daci_1768 Daci_1769 Daci_1769 ssuD ssuD Daci_1772 Daci_1772 Daci_1773 Daci_1773 Daci_1774 Daci_1774 Daci_1775 Daci_1775 Daci_1776 Daci_1776 Daci_1777 Daci_1777 Daci_1778 Daci_1778 Daci_1779 Daci_1779 Daci_1780 Daci_1780 metN metN Daci_1782 Daci_1782 Daci_1783 Daci_1783 Daci_1784 Daci_1784 Daci_1785 Daci_1785 Daci_1786 Daci_1786 Daci_1788 Daci_1788 Daci_2006 Daci_2006 Daci_2012 Daci_2012 Daci_2212 Daci_2212 Daci_2237 Daci_2237 Daci_2311 Daci_2311 cysS cysS Daci_2548 Daci_2548 Daci_2550 Daci_2550 Daci_2561 Daci_2561 Daci_2669 Daci_2669 Daci_2841 Daci_2841 metN-2 metN-2 Daci_3173 Daci_3173 Daci_3174 Daci_3174 cysC cysC Daci_4038 Daci_4038 Daci_4419 Daci_4419 cysA cysA Daci_4588 Daci_4588 Daci_4589 Daci_4589 Daci_4590 Daci_4590 Daci_4596 Daci_4596 Daci_4597 Daci_4597 Daci_4598 Daci_4598 Daci_4605 Daci_4605 ssuD-2 ssuD-2 Daci_4641 Daci_4641 Daci_4651 Daci_4651 Daci_4652 Daci_4652 Daci_4653 Daci_4653 Daci_4654 Daci_4654 Daci_4655 Daci_4655 Daci_4656 Daci_4656 Daci_4657 Daci_4657 Daci_4659 Daci_4659 metZ metZ Daci_4832 Daci_4832 Daci_4891 Daci_4891 Daci_4960 Daci_4960 Daci_5053 Daci_5053 Daci_5151 Daci_5151 Daci_5156 Daci_5156 Daci_5218 Daci_5218 Daci_5219 Daci_5219 thrB thrB metK metK Daci_5612 Daci_5612 Daci_5613 Daci_5613 Daci_5614 Daci_5614 Daci_5616 Daci_5616 Daci_5789 Daci_5789 Daci_5917 Daci_5917 ahcY ahcY Daci_6043 Daci_6043 metXS metXS Daci_6045 Daci_6045
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Daci_0169PFAM: homocysteine S-methyltransferase; KEGG: aav:Aave_0174 methionine synthase. (368 aa)
Daci_0232Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (918 aa)
Daci_0278TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: vei:Veis_4134 cystathionine beta-lyase. (405 aa)
Daci_0530Flavodoxin/nitric oxide synthase; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; KEGG: aav:Aave_4788 flavodoxin/nitric oxide synthase. (885 aa)
Daci_0953Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (251 aa)
Daci_1442TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aav:Aave_4297 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (305 aa)
mdcBTriphosphoribosyl-dephospho-CoA synthase; Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase; Belongs to the CitG/MdcB family. (286 aa)
Daci_1764TIGRFAM: holo-ACP synthase, malonate decarboxylase-specific; KEGG: rfr:Rfer_1847 malonate decarboxylase. (237 aa)
Daci_1765TIGRFAM: malonate decarboxylase, gamma subunit; PFAM: malonate decarboxylase gamma subunit; KEGG: mpt:Mpe_A2892 malonate decarboxylase gamma subunit. (233 aa)
Daci_1766TIGRFAM: malonate decarboxylase, beta subunit; KEGG: mpt:Mpe_A2893 beta subunit of malonate decarboxylase. (305 aa)
Daci_1767TIGRFAM: malonate decarboxylase acyl carrier protein; PFAM: malonate decarboxylase delta subunit; KEGG: mpt:Mpe_A2894 delta subunit of malonate decarboxylase. (110 aa)
Daci_1768TIGRFAM: malonate decarboxylase, alpha subunit; KEGG: mpt:Mpe_A2895 alpha subunit of malonate decarboxylase. (560 aa)
Daci_1769PFAM: Citrate transporter; Dicarboxylate carrier MatC domain protein; KEGG: mpt:Mpe_A2896 dicarboxylate carrier protein. (457 aa)
ssuDAlkanesulfonate monooxygenase; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family. (384 aa)
Daci_1772Putative sigma54 specific transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: pap:PSPA7_2908 probable transcriptional regulator. (386 aa)
Daci_1773PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: pap:PSPA7_2907 probable FMNH2-dependent monooxygenase. (393 aa)
Daci_1774PFAM: NADPH-dependent FMN reductase; KEGG: pfo:Pfl_3915 FMN reductase. (209 aa)
Daci_1775PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: xac:XAC0854 hypothetical protein. (436 aa)
Daci_1776KEGG: bxe:Bxe_B1543 putative monooxygenase, DszA family. (454 aa)
Daci_1777PFAM: NLPA lipoprotein; KEGG: ppu:PP_0221 ABC transporter, periplasmic binding protein, putative. (274 aa)
Daci_1778PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: bxe:Bxe_B1544 hypothetical protein. (425 aa)
Daci_1779PFAM: Acyl-CoA dehydrogenase type 2 domain; KEGG: aav:Aave_2009 acyl-CoA dehydrogenase, type 2, C-terminal domain. (430 aa)
Daci_1780PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pmy:Pmen_2366 binding-protein-dependent transport systems inner membrane component. (220 aa)
metNABC transporter related; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (397 aa)
Daci_1782PFAM: NLPA lipoprotein; KEGG: bur:Bcep18194_B0309 NlpA lipoprotein. (268 aa)
Daci_1783PFAM: NLPA lipoprotein; KEGG: bam:Bamb_4689 NlpA lipoprotein. (264 aa)
Daci_1784PFAM: regulatory protein MarR; KEGG: bpl:BURPS1106A_A2106 transcriptional regulator, MarR family. (190 aa)
Daci_1785PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bmn:BMA10247_A0721 hypothetical protein. (152 aa)
Daci_1786KEGG: acr:Acry_2631 conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family-like protein. (228 aa)
Daci_1788PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ajs:Ajs_2567 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa)
Daci_2006PFAM: Taurine catabolism dioxygenase TauD/TfdA; KEGG: bam:Bamb_1586 taurine dioxygenase. (282 aa)
Daci_2012PFAM: Taurine catabolism dioxygenase TauD/TfdA; KEGG: reu:Reut_A1602 taurine dioxygenase. (281 aa)
Daci_2212TIGRFAM: cysteine synthase; cysteine synthase B; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ajs:Ajs_2900 cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. (307 aa)
Daci_2237PFAM: Rhodanese domain protein; KEGG: ajs:Ajs_1033 3-mercaptopyruvate sulfurtransferase. (304 aa)
Daci_2311TIGRFAM: serine O-acetyltransferase; KEGG: aav:Aave_2076 serine O-acetyltransferase. (274 aa)
cysSKEGG: ajs:Ajs_1623 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa)
Daci_2548PFAM: NADPH-dependent FMN reductase; KEGG: rme:Rmet_5075 NADPH-dependent FMN reductase. (193 aa)
Daci_2550PFAM: Methionine synthase vitamin-B12 independent; KEGG: aav:Aave_2779 methionine synthase, vitamin-B12 independent. (341 aa)
Daci_2561PFAM: Rhodanese domain protein; KEGG: ajs:Ajs_1650 rhodanese domain protein. (324 aa)
Daci_2669PFAM: methylenetetrahydrofolate reductase; KEGG: rme:Rmet_2988 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (300 aa)
Daci_2841TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: ajs:Ajs_3160 lipoprotein, YaeC family. (261 aa)
metN-2ABC transporter related; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (348 aa)
Daci_3173PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ajs:Ajs_2344 binding-protein-dependent transport systems inner membrane component. (221 aa)
Daci_3174TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: ajs:Ajs_2342 lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. (269 aa)
cysCAdenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (228 aa)
Daci_4038PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: ajs:Ajs_2273 Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. (422 aa)
Daci_4419KEGG: pde:Pden_4106 nitrilotriacetate monooxygenase. (455 aa)
cysASulfate ABC transporter, ATPase subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (375 aa)
Daci_4588TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ajs:Ajs_2336 sulfate ABC transporter, inner membrane subunit CysW. (335 aa)
Daci_4589Sulfate ABC transporter, inner membrane subunit CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (308 aa)
Daci_4590TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: ajs:Ajs_2338 sulfate ABC transporter, periplasmic sulfate-binding protein. (342 aa)
Daci_4596PFAM: NLPA lipoprotein; KEGG: reh:H16_B2232 ABC-type transporter, periplasmic component: MUT family; Belongs to the nlpA lipoprotein family. (276 aa)
Daci_4597PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cvi:CV_2296 probable transmembrane ABC transporter protein. (221 aa)
Daci_4598ABC transporter related; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. (293 aa)
Daci_4605TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: ajs:Ajs_2342 lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. (272 aa)
ssuD-2Alkanesulfonate monooxygenase; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family. (386 aa)
Daci_4641TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: aav:Aave_3046 sulfate ABC transporter, periplasmic sulfate-binding protein. (340 aa)
Daci_4651KEGG: xcc:XCC0173 hypothetical protein. (347 aa)
Daci_4652PFAM: nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: aav:Aave_3053 nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein. (629 aa)
Daci_4653PFAM: conserved hypothetical protein; KEGG: aav:Aave_3054 uncharacterized conserved protein UCP030820. (127 aa)
Daci_4654Phosphoadenylyl-sulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. (252 aa)
Daci_4655PFAM: phosphoadenosine phosphosulfate reductase; KEGG: ajs:Ajs_1792 phosphoadenosine phosphosulfate reductase. (316 aa)
Daci_4656KEGG: aav:Aave_3056 sulfate adenylyltransferase, large subunit; TIGRFAM: sulfate adenylyltransferase, large subunit; PFAM: protein synthesis factor GTP-binding. (463 aa)
Daci_46574Fe-4S ferredoxin iron-sulfur binding domain protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (109 aa)
Daci_4659KEGG: ajs:Ajs_1667 hypothetical protein. (95 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (452 aa)
Daci_4832KEGG: ajs:Ajs_2286 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase. (449 aa)
Daci_4891PFAM: Taurine catabolism dioxygenase TauD/TfdA; KEGG: vha:VIBHAR_02787 hypothetical protein. (273 aa)
Daci_4960KEGG: ajs:Ajs_1656 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (432 aa)
Daci_5053Flavodoxin/nitric oxide synthase; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; flavodoxin/nitric oxide synthase; KEGG: har:HEAR3398 oxidoreductase binding flavins likely to be involved in sulfur metabolism (CysJ: sulfite reductase alpha subunit). (461 aa)
Daci_5151PFAM: Rhodanese domain protein; KEGG: mms:mma_0256 thiosulfate sulfurtransferase. (321 aa)
Daci_5156PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ajs:Ajs_3115 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (355 aa)
Daci_5218KEGG: ajs:Ajs_3205 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (475 aa)
Daci_5219PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: ajs:Ajs_3206 homoserine dehydrogenase. (449 aa)
thrBKEGG: ajs:Ajs_3320 homoserine kinase; TIGRFAM: homoserine kinase; PFAM: aminoglycoside phosphotransferase; Belongs to the pseudomonas-type ThrB family. (318 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (393 aa)
Daci_5612PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: reh:H16_B1477 ABC-type transporter, permease component: MUT family. (223 aa)
Daci_5613ABC transporter related; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. (388 aa)
Daci_5614PFAM: NLPA lipoprotein; KEGG: reh:H16_B1479 ABC-type transporter, periplasmic component: MUT family; Belongs to the nlpA lipoprotein family. (270 aa)
Daci_5616KEGG: pap:PSPA7_5762 homocysteine synthase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II. (475 aa)
Daci_5789KEGG: pna:Pnap_0539 serine O-acetyltransferase. (304 aa)
Daci_5917KEGG: ajs:Ajs_0620 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (275 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (476 aa)
Daci_6043TIGRFAM: methionine biosynthesis protein MetW; PFAM: Methionine biosynthesis MetW protein; Methyltransferase type 11; Methyltransferase type 12; KEGG: aav:Aave_4777 methionine biosynthesis protein MetW. (194 aa)
metXSHomoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (382 aa)
Daci_6045PFAM: protein of unknown function UPF0016; KEGG: aav:Aave_4779 protein of unknown function UPF0016. (204 aa)
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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