STRINGSTRING
Spea_0005 Spea_0005 Spea_0032 Spea_0032 Spea_0033 Spea_0033 Spea_0143 Spea_0143 Spea_0144 Spea_0144 Spea_0145 Spea_0145 Spea_0146 Spea_0146 Spea_0147 Spea_0147 Spea_0148 Spea_0148 Spea_0149 Spea_0149 Spea_0150 Spea_0150 Spea_0151 Spea_0151 Spea_0152 Spea_0152 Spea_0153 Spea_0153 Spea_0154 Spea_0154 Spea_0233 Spea_0233 Spea_0234 Spea_0234 Spea_0235 Spea_0235 Spea_0236 Spea_0236 Spea_0237 Spea_0237 Spea_0332 Spea_0332 Spea_0407 Spea_0407 yacG yacG zapD zapD coaE coaE Spea_0411 Spea_0411 Spea_0412 Spea_0412 Spea_0413 Spea_0413 Spea_0414 Spea_0414 Spea_0548 Spea_0548 Spea_0574 Spea_0574 Spea_0986 Spea_0986 Spea_1087 Spea_1087 Spea_1088 Spea_1088 Spea_1089 Spea_1089 Spea_1090 Spea_1090 Spea_1091 Spea_1091 Spea_1092 Spea_1092 Spea_1093 Spea_1093 Spea_1094 Spea_1094 Spea_1121 Spea_1121 Spea_1123 Spea_1123 Spea_1124 Spea_1124 Spea_1125 Spea_1125 Spea_1127 Spea_1127 Spea_1128 Spea_1128 Spea_1129 Spea_1129 Spea_1176 Spea_1176 rlmD rlmD Spea_1259 Spea_1259 Spea_1291 Spea_1291 rlmN rlmN Spea_1651 Spea_1651 Spea_1769 Spea_1769 Spea_1879 Spea_1879 Spea_1956 Spea_1956 Spea_1966 Spea_1966 Spea_2040 Spea_2040 Spea_2500 Spea_2500 Spea_2521 Spea_2521 Spea_2662 Spea_2662 Spea_2701 Spea_2701 Spea_2702 Spea_2702 Spea_2703 Spea_2703 Spea_2704 Spea_2704 Spea_2913 Spea_2913 Spea_3010 Spea_3010 Spea_3028 Spea_3028 Spea_3031 Spea_3031 miaB miaB Spea_3165 Spea_3165 Spea_3315 Spea_3315 Spea_3316 Spea_3316 Spea_3740 Spea_3740 Spea_3747 Spea_3747 Spea_3748 Spea_3748 Spea_3749 Spea_3749 Spea_3750 Spea_3750 Spea_3751 Spea_3751 Spea_3755 Spea_3755 Spea_3756 Spea_3756 Spea_3757 Spea_3757 Spea_3758 Spea_3758 Spea_3759 Spea_3759 Spea_3760 Spea_3760 Spea_3761 Spea_3761 Spea_3762 Spea_3762 Spea_3763 Spea_3763 Spea_3764 Spea_3764 Spea_3765 Spea_3765 Spea_3766 Spea_3766 Spea_3767 Spea_3767 Spea_3768 Spea_3768 Spea_3769 Spea_3769 Spea_3770 Spea_3770 Spea_3771 Spea_3771 Spea_3772 Spea_3772 Spea_3837 Spea_3837 Spea_4012 Spea_4012 Spea_4255 Spea_4255
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Spea_0005PFAM: Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; KEGG: shn:Shewana3_0015 putative signal transduction protein. (354 aa)
Spea_0032PFAM: Peptidoglycan-binding LysM; KEGG: slo:Shew_3735 peptidoglycan-binding LysM. (362 aa)
Spea_0033TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: shw:Sputw3181_0026 DNA protecting protein DprA. (339 aa)
Spea_0143TIGRFAM: general secretion pathway protein C; KEGG: slo:Shew_3620 general secretion pathway protein C. (305 aa)
Spea_0144TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: slo:Shew_3619 general secretion pathway protein D. (710 aa)
Spea_0145General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (523 aa)
Spea_0146TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: slo:Shew_3617 general secretion pathway protein F. (407 aa)
Spea_0147TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: slo:Shew_3616 general secretion pathway protein G. (144 aa)
Spea_0148TIGRFAM: general secretion pathway protein H; KEGG: slo:Shew_3615 general secretion pathway protein H. (210 aa)
Spea_0149TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: slo:Shew_3614 general secretion pathway protein I. (125 aa)
Spea_0150TIGRFAM: general secretion pathway protein J; KEGG: sbl:Sbal_4200 general secretion pathway protein J. (241 aa)
Spea_0151PFAM: General secretion pathway protein K; KEGG: slo:Shew_3612 general secretion pathway protein K. (326 aa)
Spea_0152General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (397 aa)
Spea_0153General secretion pathway M protein; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (158 aa)
Spea_0154PFAM: type II secretion system protein N; KEGG: slo:Shew_3609 type II secretion system protein N. (252 aa)
Spea_0233TIGRFAM: type IV pilus assembly protein PilM; KEGG: slo:Shew_0208 type IV pilus assembly protein PilM. (359 aa)
Spea_0234PFAM: Fimbrial assembly family protein; KEGG: slo:Shew_0209 fimbrial assembly family protein. (193 aa)
Spea_0235PFAM: Pilus assembly protein PilO; KEGG: sfr:Sfri_0372 pilus assembly protein, PilO. (206 aa)
Spea_0236PFAM: Pilus assembly protein PilP; KEGG: slo:Shew_0211 pilus assembly protein, PilQ. (172 aa)
Spea_0237TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB short domain; KEGG: slo:Shew_0212 type IV pilus secretin PilQ. (688 aa)
Spea_0332KEGG: sbl:Sbal_4042 Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase. (506 aa)
Spea_0407TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: slo:Shew_3444 mutator MutT protein. (129 aa)
yacGProtein of unknown function DUF329; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. (79 aa)
zapDProtein of unknown function DUF1342; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. (244 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (201 aa)
Spea_0411Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (303 aa)
Spea_0412PFAM: type II secretion system protein; KEGG: shn:Shewana3_0418 type II secretion system protein. (422 aa)
Spea_0413TIGRFAM: type IV-A pilus assembly ATPase PilB; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; KEGG: slo:Shew_3438 type IV-A pilus assembly ATPase PilB. (568 aa)
Spea_0414KEGG: sbl:Sbal_3918 methylation site containing protein. (148 aa)
Spea_0548KEGG: slo:Shew_3349 ATP-dependent protease La (LON) domain protein, putative. (197 aa)
Spea_0574KEGG: sdn:Sden_0410 putative cation efflux protein. (243 aa)
Spea_0986KEGG: slo:Shew_1018 hypothetical protein. (130 aa)
Spea_1087TIGRFAM: type IV pilus modification protein PilV; KEGG: son:SO_3528 type IV pilus assembly protein PilV. (186 aa)
Spea_1088KEGG: sbl:Sbal_1059 type IV pilus assembly protein PilW. (329 aa)
Spea_1089KEGG: sbm:Shew185_1127 type IV pilus assembly protein PilX. (145 aa)
Spea_1090KEGG: sdn:Sden_2716 type IV pilin biogenesis protein, putative. (1194 aa)
Spea_1091KEGG: shw:Sputw3181_3098 methylation site containing protein. (130 aa)
Spea_1092KEGG: she:Shewmr4_2948 hypothetical protein. (83 aa)
Spea_1093KEGG: sdn:Sden_2713 type IV pilus biogenesis protein, putative. (178 aa)
Spea_1094KEGG: slo:Shew_1109 type IV pilus biogenesis protein, putative. (170 aa)
Spea_1121Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (378 aa)
Spea_1123KEGG: slo:Shew_1133 hypothetical protein. (144 aa)
Spea_1124PFAM: protein of unknown function DUF167; KEGG: she:Shewmr4_1190 hypothetical protein; Belongs to the UPF0235 family. (90 aa)
Spea_1125PFAM: protein of unknown function YGGT; KEGG: slo:Shew_1135 protein of unknown function YGGT. (182 aa)
Spea_1127Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (233 aa)
Spea_1128TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: slo:Shew_1138 twitching motility protein. (345 aa)
Spea_1129KEGG: shw:Sputw3181_1326 twitching motility protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase. (370 aa)
Spea_1176PFAM: response regulator receiver; KEGG: vha:VIBHAR_06171 hypothetical protein. (540 aa)
rlmDRNA methyltransferase, TrmA family; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (445 aa)
Spea_1259PFAM: DNA repair protein RadC; KEGG: shm:Shewmr7_1776 DNA repair protein RadC; Belongs to the UPF0758 family. (158 aa)
Spea_1291Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: slo:Shew_1277 putative signal transduction protein. (491 aa)
rlmNRadical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (373 aa)
Spea_1651PFAM: peptidase S49; Peptidase S49 domain protein; KEGG: shm:Shewmr7_1536 peptidase S49, N-terminal domain protein. (342 aa)
Spea_1769TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: sbm:Shew185_1667 DNA internalization-related competence protein ComEC/Rec2. (812 aa)
Spea_1879KEGG: slo:Shew_2149 conserved hypothetical ABC transporter protein. (263 aa)
Spea_1956KEGG: son:SO_4159 hypothetical protein. (189 aa)
Spea_1966KEGG: slo:Shew_1837 hypothetical protein. (370 aa)
Spea_2040Hypothetical protein; KEGG: shw:Sputw3181_3605 methylation site containing protein. (188 aa)
Spea_2500Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. (193 aa)
Spea_2521KEGG: vfi:VF1617 hypothetical protein. (193 aa)
Spea_2662KEGG: slo:Shew_2489 competence protein ComEA helix-hairpin-helix repeat protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1. (105 aa)
Spea_2701KEGG: sbl:Sbal_1586 hypothetical protein. (192 aa)
Spea_2702KEGG: saz:Sama_1203 hypothetical protein. (200 aa)
Spea_2703Transcriptional regulator, CdaR; PFAM: sugar diacid recognition domain protein; KEGG: slo:Shew_2528 transcriptional regulator, CdaR. (383 aa)
Spea_2704KEGG: vch:VC0502 type IV pilin, putative. (178 aa)
Spea_2913KEGG: shw:Sputw3181_3641 hypothetical protein. (182 aa)
Spea_3010Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: saz:Sama_1005 putative signal transduction protein. (280 aa)
Spea_3028KEGG: hch:HCH_00820 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. (332 aa)
Spea_3031Type IV pilus assembly PilZ; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. (135 aa)
miaBtRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (475 aa)
Spea_3165PFAM: protein of unknown function DUF152; KEGG: slo:Shew_2949 protein of unknown function DUF152; Belongs to the multicopper oxidase YfiH/RL5 family. (248 aa)
Spea_3315KEGG: slo:Shew_3074 pilin, putative. (185 aa)
Spea_3316KEGG: sfr:Sfri_3092 methylation site containing protein. (177 aa)
Spea_3740PFAM: peptidase U62 modulator of DNA gyrase; KEGG: sbm:Shew185_0512 peptidase U62 modulator of DNA gyrase. (460 aa)
Spea_3747PFAM: peptidase U62 modulator of DNA gyrase; KEGG: slo:Shew_0410 peptidase U62, modulator of DNA gyrase. (493 aa)
Spea_3748PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: spc:Sputcn32_0580 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. (279 aa)
Spea_3749KEGG: slo:Shew_0408 hypothetical protein. (1439 aa)
Spea_3750TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: slo:Shew_0407 ribonuclease, Rne/Rng family. (502 aa)
Spea_3751Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (198 aa)
Spea_3755SMART: PA14-related domain protein; KEGG: slo:Shew_0402 MSHA biogenesis protein MshQ. (1382 aa)
Spea_3756KEGG: slo:Shew_0401 MSHA biogenesis protein MshP. (166 aa)
Spea_3757KEGG: slo:Shew_0400 methylation site containing protein. (295 aa)
Spea_3758KEGG: shw:Sputw3181_3602 methylation site containing protein. (191 aa)
Spea_3759KEGG: spc:Sputcn32_0569 MSHA pilin protein MshC. (158 aa)
Spea_3760KEGG: shm:Shewmr7_0473 methylation site containing protein. (176 aa)
Spea_3761KEGG: son:SO_4105 MSHA pilin protein MshA. (178 aa)
Spea_3762KEGG: shn:Shewana3_3657 methylation site containing protein. (202 aa)
Spea_3763KEGG: shn:Shewana3_3658 hypothetical protein. (163 aa)
Spea_3764PFAM: type II secretion system protein; KEGG: shw:Sputw3181_3608 type II secretion system protein. (406 aa)
Spea_3765PFAM: type II secretion system protein E; General secretory system II protein E domain protein; KEGG: slo:Shew_0392 type II secretion system protein E. (577 aa)
Spea_3766PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: she:Shewmr4_3484 tetratricopeptide TPR_2 repeat protein. (428 aa)
Spea_3767KEGG: sbm:Shew185_0485 MSHA biogenesis protein MshM. (302 aa)
Spea_3768TIGRFAM: pilus (MSHA type) biogenesis protein MshL; PFAM: type II and III secretion system protein; Secretin domain protein; Secretin/TonB short domain; KEGG: slo:Shew_0389 pilus (MSHA type) biogenesis protein MshL. (556 aa)
Spea_3769Hypothetical protein; KEGG: shn:Shewana3_3664 MSHA biogenesis protein MshK. (112 aa)
Spea_3770KEGG: slo:Shew_0387 MSHA biogenesis protein MshJ. (218 aa)
Spea_3771PFAM: Fimbrial assembly family protein; KEGG: slo:Shew_0386 fimbrial assembly family protein. (202 aa)
Spea_3772KEGG: sbm:Shew185_0480 conserved hypothetical biogenesis protein MshI. (293 aa)
Spea_3837PFAM: DNA repair protein RadC; KEGG: slo:Shew_3481 DNA repair protein RadC; Belongs to the UPF0758 family. (225 aa)
Spea_4012KEGG: shw:Sputw3181_0113 competence protein ComF. (249 aa)
Spea_4255KEGG: slo:Shew_0364 MshA, mannose-sensitive haemaglutinin. (176 aa)
Your Current Organism:
Shewanella pealeana
NCBI taxonomy Id: 398579
Other names: S. pealeana ATCC 700345, Shewanella pealeana ATCC 700345, Shewanella pealeana str. ATCC 700345, Shewanella pealeana strain ATCC 700345
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