STRINGSTRING
Spea_1523 Spea_1523 Spea_1560 Spea_1560 Spea_1652 Spea_1652 nadE nadE cobB cobB dapE dapE Spea_2201 Spea_2201 Spea_2226 Spea_2226 astE astE Spea_2254 Spea_2254 Spea_0223 Spea_0223 def-2 def-2 hisH hisH Spea_2660 Spea_2660 Spea_2914 Spea_2914 Spea_3268 Spea_3268 Spea_3543 Spea_3543 def def Spea_3748 Spea_3748 Spea_0226 Spea_0226 Spea_0416 Spea_0416 Spea_0944 Spea_0944 Spea_0978 Spea_0978 Spea_1102 Spea_1102 lpxC lpxC glsA glsA pyrG pyrG Spea_1204 Spea_1204 Spea_1348 Spea_1348 cheB cheB Spea_1405 Spea_1405
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Spea_1523KEGG: pha:PSHAb0157 putative N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. (378 aa)
Spea_1560PFAM: protein of unknown function DUF437; KEGG: vvy:VVA0554 hypothetical protein; Belongs to the UPF0267 family. (104 aa)
Spea_1652PFAM: protein of unknown function DUF437; KEGG: sbl:Sbal_2524 uncharacterised conserved protein UCP029143; Belongs to the UPF0267 family. (103 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (276 aa)
cobBPFAM: Silent information regulator protein Sir2; KEGG: slo:Shew_1662 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. (241 aa)
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (381 aa)
Spea_2201KEGG: ehi:379.t00002 conserved hypothetical protein Pfam: Macro SIR2 PROSITE: SIRTUIN. (289 aa)
Spea_2226KEGG: slo:Shew_1997 Bax protein, putative. (275 aa)
astESuccinylglutamate desuccinylase/aspartoacylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (345 aa)
Spea_2254TIGRFAM: L-asparaginase, type I; PFAM: Asparaginase/glutaminase; KEGG: slo:Shew_1940 L-asparaginases, type I. (338 aa)
Spea_0223TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: sbm:Shew185_4098 competence/damage-inducible protein CinA; Belongs to the CinA family. (424 aa)
def-2Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (163 aa)
hisHImidazoleglycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (247 aa)
Spea_2660PFAM: histone deacetylase superfamily; KEGG: she:Shewmr4_2474 histone deacetylase superfamily. (304 aa)
Spea_2914PFAM: peptidase S45 penicillin amidase; KEGG: slo:Shew_2669 penicillin amidase. (770 aa)
Spea_3268KEGG: vfi:VF1097 BAX protein. (307 aa)
Spea_3543N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: slo:Shew_0563 N-acetylmuramoyl-L-alanine amidase. (440 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (199 aa)
Spea_3748PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: spc:Sputcn32_0580 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. (279 aa)
Spea_0226TIGRFAM: acetylornithine deacetylase (ArgE); PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: slo:Shew_0201 acetylornithine deacetylase (ArgE). (383 aa)
Spea_0416PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: slo:Shew_3434 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD. (180 aa)
Spea_0944PFAM: peptidase C26; KEGG: slo:Shew_0971 peptidase C26. (253 aa)
Spea_0978KEGG: slo:Shew_3159 uncharacterized FlgJ-related protein-like. (354 aa)
Spea_1102KEGG: son:SO_3505 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. (377 aa)
lpxCUDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (306 aa)
glsAPFAM: Glutaminase, core; KEGG: sbm:Shew185_3050 glutaminase; Belongs to the glutaminase family. (304 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (546 aa)
Spea_1204PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: vpa:VP1774 putative carbon-nitrogen hydrolase. (290 aa)
Spea_1348KEGG: son:SO_3241 flagellar protein FlgJ; TIGRFAM: flagellar rod assembly protein/muramidase FlgJ; PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; SMART: Lysozyme subfamily 2. (363 aa)
cheBResponse regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (393 aa)
Spea_1405PFAM: peptidase C26; KEGG: nph:NP1950A sugar metabolism cluster protein (predicted glutamine amidotransferases). (209 aa)
Your Current Organism:
Shewanella pealeana
NCBI taxonomy Id: 398579
Other names: S. pealeana ATCC 700345, Shewanella pealeana ATCC 700345, Shewanella pealeana str. ATCC 700345, Shewanella pealeana strain ATCC 700345
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