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| | thlA | KEGG: jan:Jann_4050 acetyl-CoA C-acetyltransferase TIGRFAM: acetyl-CoA acetyltransferase PFAM: Thiolase; good swissprot hit to Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase) from Clostridium acetobutylicum; found domain accords to thiolase II; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | imdh | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (368 aa) |
| | ipmi2 | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | ipmi1 | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa) |
| | ilvD1 | KEGG: rde:RD1_0332 dihydroxy-acid dehydratase TIGRFAM: dihydroxy-acid dehydratase PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Swissprot: high similarity to dihydroxyacid dehydratase from Loktanella vestfoldensis SKA53; Belongs to the IlvD/Edd family. (577 aa) |
| | accD | acetyl-CoA carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (320 aa) |
| | mmgC | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain KEGG: rde:RD1_1372 isobutyryl-CoA dehydrogenase. (564 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (532 aa) |
| | hbdA | PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding KEGG: sil:SPO0717 3-hydroxybutyryl-CoA dehydrogenase; high swissprot, good RBS site AGGAT. (291 aa) |
| | eftA | PFAM: Electron transfer flavoprotein alpha/beta-subunit; Electron transfer flavoprotein alpha subunit KEGG: rde:RD1_1387 electron transfer flavoprotein, alpha subunit, high swissprot. (308 aa) |
| | eftB | PFAM: Electron transfer flavoprotein alpha/beta-subunit KEGG: sil:SPO0720 electron transfer flavoprotein, beta subunit; high swissprot to Electron transfer flavoprotein subunit beta from Paracoccus denitrificans. (252 aa) |
| | pykA | KEGG: rsp:RSP_1766 pyruvate kinase TIGRFAM: pyruvate kinase PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; high swissprot; Belongs to the pyruvate kinase family. (482 aa) |
| | merA | Putative mercuric reductase MerA; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; high swissprot to Mercuric reductase from Bacillus cereus and high Ref ZP hit to mercuric reductase, putative from Roseovarius sp. TM1035. (470 aa) |
| | Dshi_0336 | PFAM: SNARE associated Golgi protein KEGG: rde:RD1_1463 mercuric reductase; the mercuric reductase MerA also comprises a SNARE associated Golgi protein motif, low swissprot hit to UPF0043 membrane protein ydjX from Escherichia coli K12 and good Ref ZP hit to hypothetical protein RCCS2_07124 from Roseobacter sp. CCS2; also good Ref YP hit to mercuric reductase from Roseobacter denitrificans OCh 114; possible Gene arrangement with Dshi_0335. (243 aa) |
| | fadD3 | PFAM: AMP-dependent synthetase and ligase, good swissprot hit to Putative long-chain-fatty-acid--CoA ligase from Haemophilus influenzae and high Ref ZP hit to AMP-binding enzyme from Rhodobacterales bacterium HTCC2654; NCBI conserved domains: COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (656 aa) |
| | pdhA2 | PFAM: dehydrogenase E1 component; good swissprot hit to Pyruvate dehydrogenase E1 component subunit alpha from Zymomonas mobilis; high Ref YP hit to dehydrogenase E1 component [Sinorhizobium medicae WSM419]. (339 aa) |
| | pdhB1 | Pyruvate dehydrogenase E1 component subunit beta; PFAM: Transketolase central region; Transketolase domain protein; high swissprot hit to Pyruvate dehydrogenase E1 component subunit beta from Rickettsia bellii RML369-C; high Ref YP hit to Transketolase central region [Sinorhizobium medicae WSM419]; Transketolase central region. (327 aa) |
| | pdhC2 | Dihydrolipoamide acetyltransferase; PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; middle swissprot hit to Acetoin dehydrogenase E2 component from Pseudomonas putida; high Ref YP hit to branched-chain alpha-keto acid dehydrogenase subunit E2 from Sinorhizobium medicae WSM419; unsure GC frame plot; pyruvate dehydrogenase E2 component. (398 aa) |
| | Dshi_0537 | PFAM: carbohydrate kinase FGGY; NCBI conserved domains: AraB, XylB; good swissprot hit to Ribulokinase from Bacillus clausii KSM-K16; high Ref YP hit to carbohydrate kinase FGGY [Sinorhizobium medicae WSM419]. (497 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (525 aa) |
| | Dshi_0688 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; NCBI conserved domains: PRK06481, fumarate reductase flavoprotein subunit, COG1053, SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; middle swissprot hit to Fumarate reductase flavoprotein subunit precursor from Shewanella oneidensis; high Ref YP hit to fumarate reductase/succinate dehydrogenase flavoprotein-like from Jannaschia sp. CCS1. (454 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (464 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (219 aa) |
| | atoDA | Acyl CoA:acetate/3-ketoacid CoA transferase, alpha and beta subunit; PFAM: coenzyme A transferase; NCBI conserved domains: atoDA; low swissprot hit to SCOT-S from Sus scrofa; high Ref ZP hit to Coenzyme A transferase [Roseobacter litoralis Och 149]. (648 aa) |
| | pccB | Carboxyl transferase; Probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits. (510 aa) |
| | pccA | Carbamoyl-phosphate synthase L chain ATP-binding; Biotin-dependent enzyme, Probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits. (681 aa) |
| | bhbA | methylmalonyl-CoA mutase, large subunit; Catalyzes the interconversion of succinyl-CoA and methylmalonyl-CoA during the polyhydroxyalkanoate degradation pathway. cobalamin-dependent, homodimer. (712 aa) |
| | ttuC | Tartrate dehydrogenase; Multiple catalytic activities: EC:1.1.1.93: Tartrate + NAD(+) <=> oxaloglycolate + NADH; EC:4.1.1.73: (R,R)-tartrate <=> D-glycerate + CO2; EC:1.1.1.83: (R)-malate + NAD(+) <=> pyruvate + CO(2) + NADH; cytoplasmatic; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (359 aa) |
| | Dshi_0825 | AMP-binding domain, ligase similar to propionate-CoA and Acetyl-CoA ligase. (630 aa) |
| | Dshi_0826 | Malic protein NAD-binding; Malate decarboxylase, NAD(P) dependent(two forms of the enzyme with different kinetics), Reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH. (759 aa) |
| | fadJ | 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Multifunctional enzyme: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase, Reaction: (3S)-3-Hydroxyacyl-CoA <=> trans-2,3-Dehydroacyl-CoA + H2O, Reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA; 3-hydroxyacyl-CoA dehydrogenase, Reaction(EC:1.1.1.35):(3S)-3-Hydroxyacyl-CoA + NAD+ <=> 3-Oxoacyl-CoA + NADH + H+. (737 aa) |
| | fadA | Thiolase, Reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa) |
| | Dshi_0838 | Contains all Acyl-CoA dehydrogenase domains; Reaction: Acyl-CoA + Acceptor <=> 2,3-Dehydroacyl-CoA + Reduced acceptor. (382 aa) |
| | Dshi_0839 | acyl-CoA dehydrogenase domain protein; Oxidoreductase acting on the CH-CH group of donors with other acceptors. (592 aa) |
| | lldD2 | FMN-dependent dehydrogenase, Reaction: (S)-lactate + 2 ferricytochrome c <=> pyruvate + 2 ferrocytochrome c + 2 H+; cytochrome. (390 aa) |
| | Dshi_0999 | Bile acid:sodium symporter; Found both in prokaryotes and eukaryotes; related to the human bile acid:sodium symporters; transmembrane proteins. (293 aa) |
| | fadD4 | AMP-dependent synthetase and ligase; Esterification and transport of exogeneous long chain fatty acids, Reaction: ATP + a long-chain carboxylic acid + CoA <=> AMP + diphosphate + an acyl-CoA. (573 aa) |
| | serA2 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; NAD-binding, Reaction: 2-hydroxyglutarate + NAD+ <=> 2-oxoglutarate + NADH; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa) |
| | Dshi_1003 | Aminoglycoside phosphotransferase; This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides. (337 aa) |
| | Dshi_1004 | acyl-CoA dehydrogenase domain protein; Contains middle and C-terminal domain, N-terminal domain not conserved. (405 aa) |
| | Dshi_1058 | acyl-CoA dehydrogenase domain protein; N-terminal, middle and C-terminal domain, Oxidoreductase acting on the CH-CH group of donors with other acceptors. (396 aa) |
| | Dshi_1134 | 3-oxoacid CoA-transferase, B subunit; Reaction: Succinyl-CoA + a 3-oxo acid <=> succinate + a 3-oxoacyl-CoA. (208 aa) |
| | Dshi_1136 | 3-oxoacid CoA-transferase, A subunit; Reaction: Succinyl-CoA + a 3-oxo acid <=> succinate + a 3-oxoacyl-CoA. (231 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (724 aa) |
| | Dshi_1254 | Glyceraldehyde-3-phosphate dehydrogenase; Tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis; type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (340 aa) |
| | Dshi_1258 | Short-chain dehydrogenase/reductase SDR; Most enzymes of this family are NAD/NADP-dependent oxidoreductases. (247 aa) |
| | fbaA | Ketose-bisphosphate aldolase; Zinc-dependent, homodimeric enzyme. (280 aa) |
| | ivd | acyl-CoA dehydrogenase domain protein; FAD-dependent, Reaction: 3-methylbutanoyl-CoA + acceptor = 3-methylbut-2-enoyl-CoA + reduced acceptor. (387 aa) |
| | mccB | propionyl-CoA carboxylase; Involved in leucine catabolism. (534 aa) |
| | mccA | Carbamoyl-phosphate synthase L chain ATP-binding; Involved in leucine catabolism. (661 aa) |
| | mvaB | hydroxymethylglutaryl-CoA lyase; Involved ketogenesis and leucine catabolism. (287 aa) |
| | mvaA | enoyl-CoA hydratase/isomerase; Involved ketogenesis and leucine catabolism. (262 aa) |
| | dld1 | D-lactate dehydrogenase; Catalyzes the stereospecific oxidation of D-lactate to pyruvate; cytochrome. (468 aa) |
| | Dshi_1366 | Aminotransferase class-III; Similar to omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (441 aa) |
| | accC | acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | accB | acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (175 aa) |
| | acsA | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (653 aa) |
| | Dshi_1426 | Hydro-lyase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (504 aa) |
| | Dshi_1430 | This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor. (487 aa) |
| | Dshi_1544 | Short-chain dehydrogenase/reductase family protein; SWISSPROT P99093: 3-oxoacyl-[acyl-carrier-protein] reductase fabG; TIGRFAM: TIGR01963 3-hydroxybutyrate dehydrogenase; PRINTS: PR00080, PR00081; PANTHER: PTHR19410, PFAM: PF00106 short chain dehydrogenase/reductase, SUPERFAMILY: SSF51735, Gene3D: G3DSA:3.40.50.720, COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (257 aa) |
| | Dshi_1600 | Monooxygenase; COG: COG2329-Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides; PFAM: pfam03992; SUPERFAMILY: SSF54909. (103 aa) |
| | Dshi_1603 | Putative thioesterase superfamily protein; TIGRFAM: TIGR00369-Phenylacetic acid degradation-related protein; COG: COG2050-Uncharacterized protein, possibly involved in aromatic compounds catabolism; PFAM: PF03061; SWISSPROT Q9I644: UPF0152 protein PA0474, P76084: Phenylacetic acid degradation protein paaI; similar to Phenylacetic acid degradation protein paaI. (140 aa) |
| | Dshi_1604 | COG: COG1024-Enoyl-CoA hydratase/carnithine racemase; PFAM: pfam00378; SWISSPROT P76082: Probable enoyl-CoA hydratase paaF. (264 aa) |
| | Dshi_1621 | SWISSPROT: 6-phosphofructokinase isozyme 2 (Phosphofructokinase-2) [pfkB]; PROSITE: PS00583; PFAM: PF00294; SUPERFAMILY: SSF53613; Belongs to the carbohydrate kinase PfkB family. (316 aa) |
| | glk | Glucokinase; SWISSPROT P64254: Glucokinase; TIGRFAM: TIGR00749 glucokinase, proteobacterial type; COG: COG0837; PFAM: PF02685; SUPERFAMILY: SSF53067; Belongs to the bacterial glucokinase family. (323 aa) |
| | pgi | COG: COG0166 - Glucose-6-phosphate isomerase; PFAM: PF00342; SPRINT: PR00662; PROSITE: PS00174, PS00765; SUPERFAMILY: SSF53697; Belongs to the GPI family. (534 aa) |
| | pgl | Putative 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (224 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (484 aa) |
| | Dshi_1696 | alpha-IPM synthetase/homocitrate synthase family transferase; TIGRFAM: TIGR00977 2-isopropylmalate synthase/homocitrate synthase family protein; COG: COG0119; PFAM: PF00682, PF08502; PROSITE: PS00815, PS00816; SUPERFAMILY: SSF110921, SSF51569; Belongs to the alpha-IPM synthase/homocitrate synthase family. (545 aa) |
| | tktA | Transketolase 1; SWISSPROT P27302: Transketolase 1; TIGRFAM: TIGR00232 transketolase, bacterial and yeast; COG: COG0021; PFAM: pfam00456, pfam02779, pfam02780; Belongs to the transketolase family. (657 aa) |
| | gap2 | SWISSPROT P00362: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: TIGR01534 glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057 - Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; PFAM: pfam02800 pfam00044; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa) |
| | gap1 | SWISSPROT P00362: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: TIGR01534 glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057 - Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; PFAM: pfam02800 pfam00044; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (340 aa) |
| | mmsA | SWISSPROT P28810: Methylmalonate-semialdehyde dehydrogenase [acylating]; TIGRFAM: TIGR01722 methylmalonic acid semialdehyde dehydrogenase; PANTHER: PTHR11699:SF27; PFAM: PF00171; PROSITE: PS00070; COG: COG1012 - NAD-dependent aldehyde dehydrogenases. (499 aa) |
| | Dshi_1750 | acyl-CoA dehydrogenase; PFAM: PF00441, PF02770, PF02771; PROSITE: PS00072, PS00073; COG: COG1960 - Acyl-CoA dehydrogenases. (381 aa) |
| | Dshi_1751 | enoyl-CoA hydratase/isomerase family protein; COG: COG1024 - Enoyl-CoA hydratase/carnithine racemase; PFAM: PF00378; Gene3D: G3DSA:3.90.226.10. (348 aa) |
| | mmsB | TIGRFAM: TIGR01692 3-hydroxyisobutyrate dehydrogenase; PANTHER: PTHR22981; PROSITE: PS00895; PFAM: PF03446; Gene3D: G3DSA:1.10.1040.10; Belongs to the HIBADH-related family. (291 aa) |
| | Dshi_1753 | COG: COG1024 - Enoyl-CoA hydratase/carnithine racemase; PFAM: PF00378; PROSITE: PS00166; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa) |
| | eda | SWISSPROT P0A955: KHG/KDPG aldolase; PFAM: PF01081; TIGRFAM: TIGR01182; COG: COG0800 - 2-keto-3-deoxy-6-phosphogluconate aldolase. (213 aa) |
| | edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (601 aa) |
| | ilvI | SWISSPROT P00893: Acetolactate synthase isozyme 3 large subunit; TIGRFAM: TIGR00118 acetolactate synthase, large subunit, biosynthetic type; COG: COG0028 - Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; PFAM: PF02775, PF00205, PF02776. (585 aa) |
| | ilvH | SWISSPROT P00894: Acetolactate synthase isozyme 3 small subunit; TIGRFAM: TIGR00119 acetolactate synthase, small subunit; PFAM: PF01842. (190 aa) |
| | gltA2 | SWISSPROT P0ABH7: Citrate synthase; TIGR01798 citrate synthase I (hexameric type); COG: COG0372; PFAM: PF00285; PROSITE: PS00480; PRINTS: PR00143; Belongs to the citrate synthase family. (430 aa) |
| | lpdV | SWISSPROT Q9I1L9: Dihydrolipoyl dehydrogenase; TIGRFAM: TIGR01350; PFAM: PF00070, PF02852, PF07992. (465 aa) |
| | acnA | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (928 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa) |
| | lpdA | SWISSPROT P0A9P0: Dihydrolipoyl dehydrogenase; PFAM: PF00364, PF00070, PF02852, PF07992; PROSITE: PS50968, PS00189, PS00076; PRINTS: PR00945, PR00411, PR00368; TIGRFAM: TIGR01350 dihydrolipoamide dehydrogenase; COG: COG1249 - Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (580 aa) |
| | aceF | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (433 aa) |
| | aceE | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (885 aa) |
| | rbsK | Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (305 aa) |
| | pgm | SWISSPROT P39671: Phosphoglucomutase; COG: COG0033 - Phosphoglucomutase; PFAM: PF02880, PF02879, PF02878, PF00408. (543 aa) |
| | acnB | SWISSPROT P36683: Aconitate hydratase 2; TIGRFAM: TIGR00117 aconitate hydratase 2; COG: COG1049 - Aconitase B; PFAM: PF00330, PF06434; SUPERFAMILY: SSF53732, SSF52016, SSF74778. (930 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (247 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (424 aa) |
| | pgk | Swiss-Prot: P0A799-Phosphoglycerate kinase PFAM: phosphoglycerate kinase KEGG: jan:Jann_1694 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (393 aa) |
| | fda | Swiss-Prot: Q07159-Fructose-bisphosphate aldolase class 1 PFAM: fructose-bisphosphate aldolase class-I. (294 aa) |
| | pdhA1 | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (331 aa) |
| | pdhB2 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (451 aa) |
| | pdhC1 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (420 aa) |
| | glpX | Swiss-Prot: P0A9C9 - Fructose-1,6-bisphosphatase class II glpX TIGRFAM: fructose-1,6-bisphosphatase, class II PFAM: GlpX family protein KEGG: rsq:Rsph17025_0833 fructose-1,6-bisphosphatase, class II. (323 aa) |
| | Dshi_2319 | Putative quinone oxidoreductase; Swiss-Prot: P26646-Protein yhdH TIGRFAM: Quinone oxidoreductase putative YhdH/YhfP PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; YhdH. (328 aa) |
| | fumC | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa) |
| | Dshi_2357 | COG1960: Acyl-CoA dehydrogenases PFAM: Acyl-CoA dehydrogenase. (406 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa) |
| | Dshi_2401 | Swiss-Prot: P22983-Pyruvate, phosphate dikinase TIGR01828: pyruvate, phosphate dikinase PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region KEGG: rde:RD1_1948 pyruvate, phosphate dikinase. (862 aa) |
| | lldD1 | Swiss-Prot: P33232- L-lactate dehydrogenase [cytochrome] lldD PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase KEGG: sit:TM1040_2026 L-lactate dehydrogenase (cytochrome). (389 aa) |
| | Dshi_2485 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1145 aa) |
| | sucC2 | succinyl-CoA synthetase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa) |
| | sucD2 | ADP-forming succinyl-CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (299 aa) |
| | Dshi_2566 | Putative bifunctional enzyme; PFAM: dehydrogenase E1 component; Transketolase central region; Transketolase domain protein; transketolase / dehydrogenase. (743 aa) |
| | Dshi_2582 | Swiss-Prot: P27254-LAO/AO transport system kinase TIGRFAM: LAO/AO transport system ATPase PFAM: ArgK protein. (358 aa) |
| | Dshi_2602 | Swiss-Prot: Q06319-Acyl-CoA dehydrogenase, short-chain specific PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain KEGG: rde:RD1_0250 acyl-CoA dehydrogenase, putative. (401 aa) |
| | Dshi_2630 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase Swiss-Prot: P54540-Uncharacterized protein yqjC. (134 aa) |
| | gap3 | Swiss-Prot: P09124-Glyceraldehyde-3-phosphate dehydrogenase 1 PFAM: glyceraldehyde 3-phosphate dehydrogenase TIGR01534 glyceraldehyde-3-phosphate dehydrogenase, type I; phosphorylating; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (329 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (260 aa) |
| | Dshi_2776 | Swiss-Prot: P12311-Alcohol dehydrogenase PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (319 aa) |
| | Dshi_2837 | Aminotransferase; Swiss-Prot: P0AB80-Branched-chain-amino-acid aminotransferase PFAM: aminotransferase class IV; class IV. (286 aa) |
| | Dshi_2853 | Alcohol dehydrogenase; TIGRFAM: crotonyl-CoA reductase PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein Swiss-Prot: P42328-Alcohol dehydrogenase. (430 aa) |
| | mutB | Swiss-Prot: PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein TIGR00640: methylmalonyl-CoA mutase C-terminal domain TIGR00641: methylmalonyl-CoA mutase N-terminal domain. (657 aa) |
| | sdhB | Swiss-Prot: P07014-Succinate dehydrogenase iron-sulfur subunit TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein KEGG: rde:RD1_1630 succinate dehydrogenase, iron-sulfur protein; iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa) |
| | sdhA | SWISSPROT P0AC41: Succinate dehydrogenase flavoprotein subunit; TIGRFAM: TIGR01812 succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative/mitochondrial subgroup; TIGR01816 succinate dehydrogenase, flavoprotein subunit, E. coli/mitochondrial subgroup; COG: COG1053 - Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; PFAM: PF00890, PF02910; PROSITE: PS00504; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (600 aa) |
| | Dshi_2866 | Hypothetical protein; TIGRFAM: TIGR02968 succinate dehydrogenase, hydrophobic membrane anchor protein; COG: COG2142 - Succinate dehydrogenase, hydrophobic anchor subunit; similar to succinate dehydrogenase. (123 aa) |
| | Dshi_2867 | SWISSPROT P69054: Succinate dehydrogenase cytochrome b556 subunit sdhC; TIGRFAM: TIGR02970 succinate dehydrogenase, cytochrome b556 subunit; COG: COG2009 - Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; PFAM: PF01127 - Succinate dehydrogenase cytochrome b subunit; PIR: PIRSF000178 - succinate dehydrogenase, cytochrome b560 subunit; PROSITE: PS01001. (127 aa) |
| | Dshi_2871 | Putative thiol ester dehydrase/isomerase; COG: COG2030 - Acyl dehydratase; PIR: PIRSF021494; SUPERFAMILY: SSF54637. (343 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa) |
| | sucC1 | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa) |
| | sucD1 | succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa) |
| | sucA | SWISSPROT P0AFG3: 2-oxoglutarate dehydrogenase E1 component; PIR: PIRSF000157 - 2-oxoglutarate dehydrogenase, E1 component; TIGRFAM: TIGR00239 2-oxoglutarate dehydrogenase, E1 component; COG: COG0567 - 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes; PFAM: PF00676, PF02779. (987 aa) |
| | sucB | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (496 aa) |
| | lpd | SWISSPROT P14218: Dihydrolipoyl dehydrogenase; TIGRFAM: TIGR01350 dihydrolipoamide dehydrogenase; COG: COG1249 - Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; PFAM: PF00070, PF02852, PF07992; PRINTS: PR00945, PR00411, PR00368. (464 aa) |
| | Dshi_2914 | Putative alpha/beta hydrolase; COG: COG1075 - Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold; PROSITE: PS51257; SUPERFAMILY: SSF53474. (255 aa) |
| | Dshi_2915 | Hypothetical protein; SWISSPROT Q58549: ADP-ribose pyrophosphatase; COG: COG1051 - ADP-ribose pyrophosphatase PFAM: PF00293; PRINTS: PR00502; Gene3D: G3DSA:3.90.79.10; related to ADP-ribose pyrophosphatase. (148 aa) |
| | Dshi_2926 | Putative MaoC-like dehydratase; SWISSPROT P77455: Protein maoC; PFAM: PF01575; COG: COG2030 - Acyl dehydratase. (147 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (340 aa) |
| | rpe | PFAM: ribulose-phosphate 3-epimerase KEGG: rsp:RSP_2864 pentose-5-phosphate-3-epimerase. (232 aa) |
| | ald | PFAM: aldehyde dehydrogenase KEGG: sil:SPO3368 aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (780 aa) |
| | puuC | PFAM: aldehyde dehydrogenase KEGG: sil:SPO0097 aldehyde dehydrogenase family protein; Gamma-Glu-gamma-aminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (485 aa) |
| | glxR | 2-hydroxy-3-oxopropionate reductase; COG2084 MmsB - 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases PFAM: oxidoreductase domain protein; 6-phosphogluconate dehydrogenase NAD-binding KEGG: jan:Jann_3485 3-hydroxyisobutyrate dehydrogenase; TSAR; Tartronate semialdehyde reductase. (294 aa) |
| | atoB | KEGG: sil:SPO0326 acetyl-CoA acetyltransferase TIGRFAM: acetyl-CoA acetyltransferase PFAM: Thiolase; Acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | fabG1 | TIGRFAM: acetoacetyl-CoA reductase PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein KEGG: jan:Jann_0492 acetoacetyl-CoA reductase; 3-ketoacyl-acyl carrier protein reductase; 3-oxoacyl-[acyl-carrier-protein] reductase. (240 aa) |
| | ydiS | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (549 aa) |
| | Dshi_3085 | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain KEGG: sil:SPO0298 acyl-CoA dehydrogenase family protein; rde:RD1_3417 putative acyl-CoA. (571 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (289 aa) |
| | bktB | Beta-ketothiolase; KEGG: rde:RD1_0201 beta-ketothiolase TIGRFAM: acetyl-CoA acetyltransferase PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | Dshi_3370 | PFAM: Enoyl-CoA hydratase/isomerase KEGG: rsh:Rsph17029_0009 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa) |
| | leuB | PFAM: isocitrate/isopropylmalate dehydrogenase KEGG: rde:RD1_3789 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; Beta-IPM dehydrogenase. (357 aa) |
| | maeB | NADP-dependent malic enzyme; PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding KEGG: sit:TM1040_2877 malate dehydrogenase (oxaloacetate decarboxylating) (NADP+)., phosphate acetyltransferase; NADP-ME. (752 aa) |
| | acs | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (658 aa) |
| | dld | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (571 aa) |
