STRINGSTRING
TGAM01_v208312 TGAM01_v208312 TGAM01_v207460 TGAM01_v207460 TGAM01_v204433 TGAM01_v204433 TGAM01_v200879 TGAM01_v200879 TGAM01_v207615 TGAM01_v207615 TGAM01_v211142 TGAM01_v211142 TGAM01_v210902 TGAM01_v210902 MCM7 MCM7 TGAM01_v210036 TGAM01_v210036 TGAM01_v209043 TGAM01_v209043 TGAM01_v208785 TGAM01_v208785 TGAM01_v208805 TGAM01_v208805 TGAM01_v208743 TGAM01_v208743 TGAM01_v208605 TGAM01_v208605 TGAM01_v208537 TGAM01_v208537 TGAM01_v208049 TGAM01_v208049 TGAM01_v207682 TGAM01_v207682 TGAM01_v207552 TGAM01_v207552 TGAM01_v207551 TGAM01_v207551 TGAM01_v207278 TGAM01_v207278 TGAM01_v207047 TGAM01_v207047 TGAM01_v205866 TGAM01_v205866 TGAM01_v205422 TGAM01_v205422 TGAM01_v204740 TGAM01_v204740 TGAM01_v204821 TGAM01_v204821 TGAM01_v203616 TGAM01_v203616 TGAM01_v202447 TGAM01_v202447 TGAM01_v202467 TGAM01_v202467 TGAM01_v202296 TGAM01_v202296 TGAM01_v201533 TGAM01_v201533 TGAM01_v201711 TGAM01_v201711 TGAM01_v201748 TGAM01_v201748 TGAM01_v201876 TGAM01_v201876 TGAM01_v201041 TGAM01_v201041 TGAM01_v200644 TGAM01_v200644 TGAM01_v200809 TGAM01_v200809 TGAM01_v200405 TGAM01_v200405
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGAM01_v208312HTH myb-type domain-containing protein. (1085 aa)
TGAM01_v207460Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (499 aa)
TGAM01_v204433Checkpoint protein; Belongs to the HUS1 family. (353 aa)
TGAM01_v200879Uncharacterized protein; Belongs to the argonaute family. (998 aa)
TGAM01_v207615Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (600 aa)
TGAM01_v211142Uncharacterized protein. (695 aa)
TGAM01_v210902Stc1 domain-containing protein. (375 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (811 aa)
TGAM01_v210036Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (736 aa)
TGAM01_v209043Uncharacterized protein; Belongs to the CGI121/TPRKB family. (197 aa)
TGAM01_v208785Uncharacterized protein. (1626 aa)
TGAM01_v208805NAD-dependent histone deacetylase SIR2. (531 aa)
TGAM01_v208743AAA domain-containing protein. (1756 aa)
TGAM01_v208605Uncharacterized protein. (1621 aa)
TGAM01_v208537Small nuclear ribonucleoprotein. (179 aa)
TGAM01_v208049Chromo domain-containing protein. (289 aa)
TGAM01_v207682APH domain-containing protein. (301 aa)
TGAM01_v207552SAP domain-containing protein. (648 aa)
TGAM01_v207551ATP-dependent DNA helicase 2 subunit 1. (1135 aa)
TGAM01_v207278Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (291 aa)
TGAM01_v207047DNA helicase; Belongs to the MCM family. (721 aa)
TGAM01_v205866RNA-dependent RNA polymerase. (1287 aa)
TGAM01_v205422DNA helicase; Belongs to the MCM family. (883 aa)
TGAM01_v204740C2H2-type domain-containing protein. (474 aa)
TGAM01_v204821Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (3726 aa)
TGAM01_v203616Histone acetyltransferase type B catalytic subunit. (482 aa)
TGAM01_v202447Chromo domain-containing protein. (267 aa)
TGAM01_v202467Uncharacterized protein. (972 aa)
TGAM01_v202296DUF2439 domain-containing protein. (396 aa)
TGAM01_v201533BUD32 protein kinase. (261 aa)
TGAM01_v201711Replication factor A2. (324 aa)
TGAM01_v201748Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (139 aa)
TGAM01_v201876RNA-dependent RNA polymerase. (1271 aa)
TGAM01_v201041ATP-dependent DNA helicase 2 subunit 2. (1252 aa)
TGAM01_v200644Telo_bind domain-containing protein. (684 aa)
TGAM01_v200809Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (667 aa)
TGAM01_v200405Rif1_N domain-containing protein. (1717 aa)
Your Current Organism:
Trichoderma gamsii
NCBI taxonomy Id: 398673
Other names: BPI 872183, C.P.K. 2074, CBS 120075, CPK 2074, FMR 12636, G.J.S. 06-09, GJS 06-09, T. gamsii, Trichoderma gamsii Samuels & Druzhinina, 2006, Trichoderma sp. GJS 04-09
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