STRINGSTRING
A0A0N7KPD1 A0A0N7KPD1 A0A0P0UX66 A0A0P0UX66 A0A0P0V5P7 A0A0P0V5P7 A0A0P0V657 A0A0P0V657 A0A0P0VJ93 A0A0P0VJ93 A0A0P0WNF2 A0A0P0WNF2 Q0DGU0_ORYSJ Q0DGU0_ORYSJ P0535F09.39 P0535F09.39 EXO1 EXO1 NBS1 NBS1 Q7XHW1_ORYSJ Q7XHW1_ORYSJ MRE11 MRE11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A0N7KPD1Os08g0177600 protein. (544 aa)
A0A0P0UX66Os01g0106700 protein; Belongs to the PI3/PI4-kinase family. (2446 aa)
A0A0P0V5P7Os01g0637050 protein. (154 aa)
A0A0P0V657Os01g0660500 protein. (391 aa)
A0A0P0VJ93Os02g0497500 protein. (422 aa)
A0A0P0WNF2Os05g0463400 protein. (621 aa)
Q0DGU0_ORYSJOs05g0512000 protein. (987 aa)
P0535F09.39Serine/threonine-protein kinase ATR; Probable serine/threonine kinase. Seems to play a central role in cell-cycle regulation by transmitting DNA damage signals to downstream effectors of cell-cycle progression. May recognize the substrate consensus sequence [ST]-Q and phosphorylate histone variant H2AX to form H2AXS139ph at sites of DNA damage, thereby regulating DNA damage response mechanism (By similarity); Belongs to the PI3/PI4-kinase family. ATM subfamily. (2710 aa)
EXO1Exonuclease 1; Putative 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. May be involved in DNA mismatch repair (MMR) (By similarity). (836 aa)
NBS1Nijmegen breakage syndrome 1 protein; Component of the MRE11-RAD50-NBN complex (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex may be involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, and cell cycle checkpoint control. Functions also in the very early stages of meiosis. (560 aa)
Q7XHW1_ORYSJATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (886 aa)
MRE11Double-strand break repair protein MRE11; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. Belongs to the MRE11/RAD32 family. (705 aa)
Your Current Organism:
Oryza sativa Japonica
NCBI taxonomy Id: 39947
Other names: Japanese rice, Japonica rice, O. sativa Japonica Group, Oryza sativa (japonica cultivar-group), Oryza sativa Japonica Group, Oryza sativa subsp. japonica
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