(41 nodes) siRNA processing network (Oryza sativa Japonica)

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Your Input:
	Q6Z422_ORYSJ	Os02g0149600 protein. (666 aa)
	Q6K4E0_ORYSJ	cDNA clone:J013119F12, full insert sequence. (279 aa)
	Q6K2E7_ORYSJ	cDNA clone:J013123J20, full insert sequence. (320 aa)
	Q6H7E6_ORYSJ	cDNA clone:J023002E14, full insert sequence. (488 aa)
	OJ1653_D06.9	Ribonuclease 3-like protein 2; Cleaves double-stranded RNA (dsRNA). (317 aa)
	DCL2A	Endoribonuclease Dicer homolog 2a; Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs (By similarity). Belongs to the helicase family. Dicer subfamily. (1410 aa)
	Q10SU9_ORYSJ	THO complex subunit 1, putative, expressed. (638 aa)
	RTL1_ORYSJ	Ribonuclease 3-like protein 1; Cleaves double-stranded RNA (dsRNA). (256 aa)
	DCL3A	Endoribonuclease Dicer homolog 3a; Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs (By similarity). (1651 aa)
	DRB1	Double-stranded RNA-binding protein 1; Binds double-stranded RNA. (441 aa)
	RDR4	Probable RNA-dependent RNA polymerase 4; Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs). (1183 aa)
	RDR3	Probable RNA-dependent RNA polymerase 3; Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs). (1153 aa)
	Q5W6Y1_ORYSJ	cDNA clone:J033081J05, full insert sequence. (580 aa)
	Q5Z4U6_ORYSJ	Os06g0698859 protein. (723 aa)
	OsJ_21406	G patch domain-containing protein TGH homolog; Functions as component of microRNA (miRNA) and small interfering RNA (siRNA) biogenesis. May assist Dicer-like (DCL) proteins to efficiently process and/or recruit the precursors of miRNAs and siRNAs. (984 aa)
	Q69VQ7_ORYSJ	Os09g0298400 protein. (332 aa)
	DCL2B	Endoribonuclease Dicer homolog 2b; Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs (By similarity). Belongs to the helicase family. Dicer subfamily. (1377 aa)
	OsJ_21299	Ribonuclease 3-like protein 3; Cleaves double-stranded RNA (dsRNA). (299 aa)
	A0A0P0VD80	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1549 aa)
	A0A0P0VEX5	Os02g0152700 protein. (416 aa)
	A0A0P0VSF3	Os03g0121901 protein. (345 aa)
	A0A0P0WDW6	Os04g0572600 protein. (451 aa)
	A0A0P0WFD3	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1252 aa)
	A0A0P0WJV1	Os05g0230200 protein. (136 aa)
	A0A0P0XCJ6	Os08g0148600 protein. (107 aa)
	A0A0P0XJV4	Os09g0315050 protein. (143 aa)
	A0A0P0XQV4	Os09g0555187 protein. (298 aa)
	DCL4	Endoribonuclease Dicer homolog 4; Involved in the RNA silencing pathway. Cleaves double- stranded RNA to produce small interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs. Required for the production of 21 nucleotide siRNAs. Regulates shoot apical meristem (SAM) initiation and maintenance, leaf polarization and lemma polarity through the trans-acting siRNAS (ta-siRNAs) pathway, which probably modulate the expression of the ARF2, ARF3, ARF4, ARF14 and ARF15 genes. Can process endogenous 21 nucleotide siRNAs derived from an imperfect inverted repeat. Ma [...] (1657 aa)
	B7F972_ORYSJ	cDNA, clone: J075104N21, full insert sequence. (180 aa)
	C7J286_ORYSJ	Os05g0506200 protein. (586 aa)
	Q0D8F3_ORYSJ	cDNA clone:J013102N10, full insert sequence. (926 aa)
	RDR1	Probable RNA-dependent RNA polymerase 1; Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs); Belongs to the RdRP family. (740 aa)
	Q0E3V3_ORYSJ	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (488 aa)
	Q0IZR2_ORYSJ	Os09g0555200 protein. (318 aa)
	Q0J7Q4_ORYSJ	Os08g0171600 protein. (462 aa)
	Q0JPV9_ORYSJ	RNA-dependent RNA polymerase; Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs). Belongs to the RdRP family. (456 aa)
	DCL1	Endoribonuclease Dicer homolog 1; Involved in the RNA silencing pathway. Cleaves double- stranded RNA to produce microRNAs (miRNAs) of 21-24 nucleotides which target the selective destruction of complementary RNAs. Regulates by this way the development of the plant. May not be involved in small interfering RNAs (siRNAs) production. (1883 aa)
	SHL2	Probable RNA-dependent RNA polymerase SHL2; Involved in the RNA silencing pathway. Probably required for the generation of small interfering RNAs (siRNAs). Regulates shoot apical meristem (SAM) initiation and maintenance and leaf polarization through the trans-acting siRNAS (ta-siRNAs) pathway which probably modulates the expression of the ARF2, ARF3, ARF4, ARF14 and ARF15 genes. (1218 aa)
	RDR2	Probable RNA-dependent RNA polymerase 2; Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs); Belongs to the RdRP family. (1136 aa)
	DCL3B	Endoribonuclease Dicer homolog 3b; Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs (By similarity). Belongs to the helicase family. Dicer subfamily. (1637 aa)
	AGO7	Protein argonaute 7; Involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). Regulates shoot apical meristem (SAM) initiation and maintenance and leaf polarization through the trans-acting siRNAS (ta- siRNAs) pathway which probably modulates the expression of the ARF2, ARF3, ARF4, ARF14 and ARF15 genes. (1048 aa)

Your Current Organism:

Oryza sativa Japonica

NCBI taxonomy Id: 39947
Other names: Japanese rice, Japonica rice, O. sativa Japonica Group, Oryza sativa (japonica cultivar-group), Oryza sativa Japonica Group, Oryza sativa subsp. japonica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0P0VD80	A0A0P0VSF3	A0A0P0VD80	A0A0P0VSF3	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Os03g0121901 protein.	0.419
A0A0P0VD80	A0A0P0WFD3	A0A0P0VD80	A0A0P0WFD3	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.951
A0A0P0VD80	A0A0P0XCJ6	A0A0P0VD80	A0A0P0XCJ6	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Os08g0148600 protein.	0.453
A0A0P0VD80	A0A0P0XJV4	A0A0P0VD80	A0A0P0XJV4	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Os09g0315050 protein.	0.416
A0A0P0VD80	AGO7	A0A0P0VD80	Q75HC2	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Protein argonaute 7; Involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). Regulates shoot apical meristem (SAM) initiation and maintenance and leaf polarization through the trans-acting siRNAS (ta- siRNAs) pathway which probably modulates the expression of the ARF2, ARF3, ARF4, ARF14 and ARF15 genes.	0.831
A0A0P0VD80	B7F972_ORYSJ	A0A0P0VD80	B7F972	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	cDNA, clone: J075104N21, full insert sequence.	0.416
A0A0P0VD80	C7J286_ORYSJ	A0A0P0VD80	C7J286	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Os05g0506200 protein.	0.814
A0A0P0VD80	DCL1	A0A0P0VD80	Q8LMR2	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Endoribonuclease Dicer homolog 1; Involved in the RNA silencing pathway. Cleaves double- stranded RNA to produce microRNAs (miRNAs) of 21-24 nucleotides which target the selective destruction of complementary RNAs. Regulates by this way the development of the plant. May not be involved in small interfering RNAs (siRNAs) production.	0.419
A0A0P0VD80	DCL2A	A0A0P0VD80	Q10HL3	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Endoribonuclease Dicer homolog 2a; Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs (By similarity). Belongs to the helicase family. Dicer subfamily.	0.416
A0A0P0VD80	DCL2B	A0A0P0VD80	Q69LX2	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Endoribonuclease Dicer homolog 2b; Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs (By similarity). Belongs to the helicase family. Dicer subfamily.	0.416
A0A0P0VD80	DCL3A	A0A0P0VD80	Q5N870	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Endoribonuclease Dicer homolog 3a; Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs (By similarity).	0.453
A0A0P0VD80	DCL3B	A0A0P0VD80	Q7XD96	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Endoribonuclease Dicer homolog 3b; Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs (By similarity). Belongs to the helicase family. Dicer subfamily.	0.453
A0A0P0VD80	DCL4	A0A0P0VD80	A7LFZ6	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Endoribonuclease Dicer homolog 4; Involved in the RNA silencing pathway. Cleaves double- stranded RNA to produce small interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs. Required for the production of 21 nucleotide siRNAs. Regulates shoot apical meristem (SAM) initiation and maintenance, leaf polarization and lemma polarity through the trans-acting siRNAS (ta-siRNAs) pathway, which probably modulate the expression of the ARF2, ARF3, ARF4, ARF14 and ARF15 genes. Can process endogenous 21 nucleotide siRNAs derived from an imperfect inverted repeat. Ma [...]	0.416
A0A0P0VD80	Q0E3V3_ORYSJ	A0A0P0VD80	Q0E3V3	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.557
A0A0P0VD80	Q0J7Q4_ORYSJ	A0A0P0VD80	Q0J7Q4	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Os08g0171600 protein.	0.951
A0A0P0VD80	Q0JPV9_ORYSJ	A0A0P0VD80	Q0JPV9	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA-dependent RNA polymerase; Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs). Belongs to the RdRP family.	0.411
A0A0P0VD80	RDR1	A0A0P0VD80	Q0DXS3	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Probable RNA-dependent RNA polymerase 1; Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs); Belongs to the RdRP family.	0.438
A0A0P0VD80	RDR2	A0A0P0VD80	Q7XM31	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Probable RNA-dependent RNA polymerase 2; Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs); Belongs to the RdRP family.	0.438
A0A0P0VD80	RDR3	A0A0P0VD80	Q5QMN5	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Probable RNA-dependent RNA polymerase 3; Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).	0.411
A0A0P0VD80	RDR4	A0A0P0VD80	Q5QMN4	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Probable RNA-dependent RNA polymerase 4; Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).	0.411

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