STRINGSTRING
Q652P6_ORYSJ Q652P6_ORYSJ A0A0N7KRJ5 A0A0N7KRJ5 A0A0P0V2V1 A0A0P0V2V1 A0A0P0VE34 A0A0P0VE34 A0A0P0VE50 A0A0P0VE50 A0A0P0W932 A0A0P0W932 A0A0P0W9H9 A0A0P0W9H9 A0A0P0WSV0 A0A0P0WSV0 A0A0P0WXQ5 A0A0P0WXQ5 A0A0P0XT88 A0A0P0XT88 GME-1 GME-1 B7E8M5_ORYSJ B7E8M5_ORYSJ B7FAH8_ORYSJ B7FAH8_ORYSJ B9FFG0_ORYSJ B9FFG0_ORYSJ C7J8Q3_ORYSJ C7J8Q3_ORYSJ CLA1 CLA1 PANC PANC RIBA2 RIBA2 GLN GLN Q8S9W7_ORYSJ Q8S9W7_ORYSJ KPHMT1 KPHMT1 KPHMT2 KPHMT2 PDX12 PDX12 Q0E188_ORYSJ Q0E188_ORYSJ Q0E4D6_ORYSJ Q0E4D6_ORYSJ Q0J3L2_ORYSJ Q0J3L2_ORYSJ Q0JEX3_ORYSJ Q0JEX3_ORYSJ TPK2 TPK2 RIBF RIBF Q10F62_ORYSJ Q10F62_ORYSJ Q10I64_ORYSJ Q10I64_ORYSJ Q10MJ3_ORYSJ Q10MJ3_ORYSJ Q10SM6_ORYSJ Q10SM6_ORYSJ Q10SP1_ORYSJ Q10SP1_ORYSJ Q2QMK8_ORYSJ Q2QMK8_ORYSJ Q2QQV2_ORYSJ Q2QQV2_ORYSJ OsJ_35490 OsJ_35490 Q2QWM9_ORYSJ Q2QWM9_ORYSJ GLDH2 GLDH2 GME-2 GME-2 GLDH1 GLDH1 Q338Z4_ORYSJ Q338Z4_ORYSJ Q53NW9_ORYSJ Q53NW9_ORYSJ TPK1 TPK1 Q5JL51_ORYSJ Q5JL51_ORYSJ Q5VMP2_ORYSJ Q5VMP2_ORYSJ ADCS ADCS P0456F09.5 P0456F09.5 TPK3 TPK3 Q653D9_ORYSJ Q653D9_ORYSJ PDX11 PDX11 Q69U93_ORYSJ Q69U93_ORYSJ Q6ERP0_ORYSJ Q6ERP0_ORYSJ Q6K4A9_ORYSJ Q6K4A9_ORYSJ RIBA3 RIBA3 OsJ_23394 OsJ_23394 Q6YXT5_ORYSJ Q6YXT5_ORYSJ Q6Z0T7_ORYSJ Q6Z0T7_ORYSJ RIBA1 RIBA1 Q6Z6Y1_ORYSJ Q6Z6Y1_ORYSJ OJ1119_C05.10 OJ1119_C05.10 GABA-T GABA-T BIO3-BIO1 BIO3-BIO1 Q7EZA7_ORYSJ Q7EZA7_ORYSJ P0552F09.130-1 P0552F09.130-1 Q7XC62_ORYSJ Q7XC62_ORYSJ Q7XCS4_ORYSJ Q7XCS4_ORYSJ OSL2 OSL2 GATP2_ORYSJ GATP2_ORYSJ Q7XTZ9_ORYSJ Q7XTZ9_ORYSJ LS LS THI1 THI1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Q652P6_ORYSJcDNA clone:J023117I03, full insert sequence. (383 aa)
A0A0N7KRJ5Os10g0191600 protein; Belongs to the PdxS/SNZ family. (185 aa)
A0A0P0V2V1Os01g0363600 protein. (189 aa)
A0A0P0VE34Os02g0124600 protein. (320 aa)
A0A0P0VE50Os02g0124599 protein. (113 aa)
A0A0P0W932Os04g0360500 protein. (304 aa)
A0A0P0W9H9Os04g0361500 protein. (610 aa)
A0A0P0WSV0Os06g0142900 protein. (103 aa)
A0A0P0WXQ5Os06g0536800 protein. (122 aa)
A0A0P0XT88Os10g0209300 protein. (86 aa)
GME-1GDP-mannose 3,5-epimerase 1; Catalyzes a reversible epimerization of GDP-D-mannose that precedes the committed step in the biosynthesis of vitamin C (L- ascorbate), resulting in the hydrolysis of the highly energetic glycosyl-pyrophosphoryl linkage. Able to catalyze 2 distinct epimerization reactions and can release both GDP-L-galactose and GDP-L- gulose from GDP-mannose. (378 aa)
B7E8M5_ORYSJcDNA clone:001-116-A11, full insert sequence. (404 aa)
B7FAH8_ORYSJcDNA, clone: J100073N23, full insert sequence. (304 aa)
B9FFG0_ORYSJOs04g0450600 protein. (196 aa)
C7J8Q3_ORYSJOs11g0300400 protein. (46 aa)
CLA11-deoxy-D-xylulose-5-phosphate synthase 1, chloroplastic; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP). Is a limiting enzyme for plastidic isoprenoid biosynthesis and essential for chloroplast development (By similarity). (720 aa)
PANCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine to form pantothenate. Essential for panthotenate biosynthesis (Probable). (313 aa)
RIBA2Probable bifunctional riboflavin biosynthesis protein RIBA 2, chloroplastic; Involved in riboflavin biosynthesis. Catalyzes both the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2- butanone 4-phosphate and the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity); In the N-terminal section; belongs to the DHBP synthase family. (553 aa)
GLNHAD-superfamily hydrolase, subfamily IA, variant 3 containing protein, expressed. (397 aa)
Q8S9W7_ORYSJOs01g0687800 protein. (592 aa)
KPHMT13-methyl-2-oxobutanoate hydroxymethyltransferase 1, mitochondrial; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (364 aa)
KPHMT23-methyl-2-oxobutanoate hydroxymethyltransferase 2, mitochondrial; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (399 aa)
PDX12Probable pyridoxal 5'-phosphate synthase subunit PDX1.2; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by PDX2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme- catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers; Belongs to the PdxS/SNZ family. (313 aa)
Q0E188_ORYSJOs02g0473000 protein. (490 aa)
Q0E4D6_ORYSJOs02g0124400 protein. (290 aa)
Q0J3L2_ORYSJOs08g0566000 protein. (609 aa)
Q0JEX3_ORYSJOs04g0190000 protein. (117 aa)
TPK2Thiamine pyrophosphokinase 2; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate (TPP). TPP is an active cofactor for enzymes involved in glycolysis and energy production. Plant leaves require high levels of TPP for photosynthesis and carbohydrate metabolism (By similarity). (267 aa)
RIBFFAD synthetase, chloroplastic; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. (391 aa)
Q10F62_ORYSJThiamine biosynthesis protein thiC, putative, expressed. (639 aa)
Q10I64_ORYSJFAD-binding domain-containing protein, putative, expressed. (604 aa)
Q10MJ3_ORYSJSeed maturation protein PM36, putative, expressed. (233 aa)
Q10SM6_ORYSJRiboflavin biosynthesis protein RibD containing protein, expressed. (423 aa)
Q10SP1_ORYSJPyridoxine 5'-phosphate oxidase, putative, expressed. (205 aa)
Q2QMK8_ORYSJcDNA clone:J013069D01, full insert sequence. (309 aa)
Q2QQV2_ORYSJOxidoreductase, aldo/keto reductase family protein, expressed. (316 aa)
OsJ_35490Probable thiamine biosynthetic bifunctional enzyme, chloroplastic; Essential for thiamine biosynthesis. Bifunctional enzyme that catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP and condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). (548 aa)
Q2QWM9_ORYSJVTC2, putative, expressed. (438 aa)
GLDH2L-galactono-1,4-lactone dehydrogenase 2, mitochondrial; Involved in the biosynthesis of ascorbic acid. (583 aa)
GME-2GDP-mannose 3,5-epimerase 2; Catalyzes a reversible epimerization of GDP-D-mannose that precedes the committed step in the biosynthesis of vitamin C (L- ascorbate), resulting in the hydrolysis of the highly energetic glycosyl-pyrophosphoryl linkage. Able to catalyze 2 distinct epimerization reactions and can release both GDP-L-galactose and GDP-L- gulose from GDP-mannose (By similarity); Belongs to the NAD(P)-dependent epimerase/dehydratase family. (371 aa)
GLDH1L-galactono-1,4-lactone dehydrogenase 1, mitochondrial; Involved in the biosynthesis of ascorbic acid. (583 aa)
Q338Z4_ORYSJNAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. (548 aa)
Q53NW9_ORYSJPyridoxin biosynthesis protein ER1, putative, expressed; Belongs to the PdxS/SNZ family. (363 aa)
TPK1Thiamine pyrophosphokinase 1; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate (TPP). TPP is an active cofactor for enzymes involved in glycolysis and energy production. Plant leaves require high levels of TPP for photosynthesis and carbohydrate metabolism (By similarity). (264 aa)
Q5JL51_ORYSJOs01g0736400 protein. (450 aa)
Q5VMP2_ORYSJ7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (138 aa)
ADCSProbable aminodeoxychorismate synthase, chloroplastic; Bifunctional enzyme that catalyzes the biosynthesis of 4- amino-4-deoxychorismate (ADC) from chorismate and glutamine. In the first step, a glutamine amidotransferase generates ammonia that is channelled between the binding sites of glutamine and chorismate and used along with chorismate in the second step, catalyzed by aminodeoxychorismate synthase, to produce ADC. Required for the synthesis of 4-aminobenzoate (PABA), an important component in tetrahydrofolate biosynthesis. Does not possess ADC lyase activity (By similarity). (895 aa)
P0456F09.5Probable inositol oxygenase; Involved in the biosynthesis of UDP-glucuronic acid (UDP- GlcA), providing nucleotide sugars for cell-wall polymers. May be also involved in plant ascorbate biosynthesis (By similarity). (308 aa)
TPK3Thiamine pyrophosphokinase 3; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate (TPP). TPP is an active cofactor for enzymes involved in glycolysis and energy production. Plant leaves require high levels of TPP for photosynthesis and carbohydrate metabolism (By similarity). (267 aa)
Q653D9_ORYSJ7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (208 aa)
PDX11Probable pyridoxal 5'-phosphate synthase subunit PDX1.1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by PDX2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme- catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers; Belongs to the PdxS/SNZ family. (318 aa)
Q69U93_ORYSJcDNA clone:J033031K02, full insert sequence. (381 aa)
Q6ERP0_ORYSJNADPH:adrenodoxin oxidoreductase, mitochondrial. (499 aa)
Q6K4A9_ORYSJcDNA clone:J023043E08, full insert sequence. (189 aa)
RIBA3Probable monofunctional riboflavin biosynthesis protein RIBA 3, chloroplastic; Involved in riboflavin biosynthesis. Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity); In the C-terminal section; belongs to the GTP cyclohydrolase II family. (536 aa)
OsJ_23394Probable 1-deoxy-D-xylulose-5-phosphate synthase 2, chloroplastic; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP). Is a limiting enzyme for plastidic isoprenoid biosynthesis and essential for chloroplast development (By similarity). (713 aa)
Q6YXT5_ORYSJcDNA clone:001-204-A07, full insert sequence. (589 aa)
Q6Z0T7_ORYSJ7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (135 aa)
RIBA1Probable bifunctional riboflavin biosynthesis protein RIBA 1, chloroplastic; Involved in riboflavin biosynthesis. Catalyzes both the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2- butanone 4-phosphate and the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity); In the N-terminal section; belongs to the DHBP synthase family. (538 aa)
Q6Z6Y1_ORYSJcDNA clone:J033103H03, full insert sequence. (255 aa)
OJ1119_C05.10Probable gamma-aminobutyrate transaminase 3, mitochondrial; Transaminase that degrades gamma-amino butyric acid (GABA). Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (510 aa)
GABA-TProbable gamma-aminobutyrate transaminase 4; Transaminase that degrades gamma-amino butyric acid (GABA). Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (483 aa)
BIO3-BIO1Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial; Bifunctional enzyme that catalyzes two different reactions involved in the biotin biosynthesis. Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity); In the N-terminal section; belongs to the dethiobiotin synthetase family. (821 aa)
Q7EZA7_ORYSJcDNA clone:001-113-D10, full insert sequence. (508 aa)
P0552F09.130-1Putative dihydropterin pyrophosphokinase /dihydropteroate synthase. (532 aa)
Q7XC62_ORYSJAminotransferase, classes I and II family protein, expressed. (450 aa)
Q7XCS4_ORYSJAldo/keto reductase family protein, putative, expressed. (375 aa)
OSL2Gamma-aminobutyrate transaminase 1, mitochondrial; Transaminase that degrades gamma-amino butyric acid (GABA) and uses pyruvate as amino-group acceptor, but not 2-oxoglutarate. Not involved in the interaction with blast fungus. (516 aa)
GATP2_ORYSJProbable gamma-aminobutyrate transaminase 2, mitochondrial; Transaminase that degrades gamma-amino butyric acid (GABA). Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (497 aa)
Q7XTZ9_ORYSJcDNA clone:J013121O07, full insert sequence. (350 aa)
LS6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (221 aa)
THI1Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; B [...] (355 aa)
Your Current Organism:
Oryza sativa Japonica
NCBI taxonomy Id: 39947
Other names: Japanese rice, Japonica rice, O. sativa Japonica Group, Oryza sativa (japonica cultivar-group), Oryza sativa Japonica Group, Oryza sativa subsp. japonica
Server load: low (28%) [HD]