STRINGSTRING
DCL2A DCL2A A0A0P0V142 A0A0P0V142 A0A0P0VLZ4 A0A0P0VLZ4 A0A0P0W4J5 A0A0P0W4J5 DCL4 DCL4 AGO4B AGO4B AGO11 AGO11 Q10LD9_ORYSJ Q10LD9_ORYSJ DCL3A DCL3A AGO15 AGO15 AGO1D AGO1D DCL2B DCL2B AGO18 AGO18 PHN1 PHN1 AGO1A AGO1A AGO17 AGO17 AGO1C AGO1C AGO16 AGO16 AGO14 AGO14 AGO7 AGO7 DCL3B DCL3B AGO1B AGO1B AGO3 AGO3 AGO2 AGO2 AGO12 AGO12 MEL1 MEL1 AGO13 AGO13 DCL1 DCL1 AGO4A AGO4A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DCL2AEndoribonuclease Dicer homolog 2a; Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs (By similarity). Belongs to the helicase family. Dicer subfamily. (1410 aa)
A0A0P0V142Os01g0275200 protein. (467 aa)
A0A0P0VLZ4Os02g0616300 protein. (331 aa)
A0A0P0W4J5Os03g0789466 protein. (457 aa)
DCL4Endoribonuclease Dicer homolog 4; Involved in the RNA silencing pathway. Cleaves double- stranded RNA to produce small interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs. Required for the production of 21 nucleotide siRNAs. Regulates shoot apical meristem (SAM) initiation and maintenance, leaf polarization and lemma polarity through the trans-acting siRNAS (ta-siRNAs) pathway, which probably modulate the expression of the ARF2, ARF3, ARF4, ARF14 and ARF15 genes. Can process endogenous 21 nucleotide siRNAs derived from an imperfect inverted repeat. Ma [...] (1657 aa)
AGO4BProtein argonaute 4B; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (911 aa)
AGO11Protein argonaute 11; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (892 aa)
Q10LD9_ORYSJcDNA clone:J033003M11, full insert sequence. (836 aa)
DCL3AEndoribonuclease Dicer homolog 3a; Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs (By similarity). (1651 aa)
AGO15Protein argonaute 15; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (889 aa)
AGO1DProtein argonaute 1D; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (1038 aa)
DCL2BEndoribonuclease Dicer homolog 2b; Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs (By similarity). Belongs to the helicase family. Dicer subfamily. (1377 aa)
AGO18Protein argonaute 18; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (1088 aa)
PHN1Protein argonaute PNH1; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). Plays a role in the maintenance of the indeterminate state of the stem cells in the shoot apical meristem (SAM). Regulates leaf formation through vascular development and may be involved in determining the central domain of the leaf founder region; Belongs to the argonaute family. Ago subfamily. (979 aa)
AGO1AProtein argonaute 1A; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (1082 aa)
AGO17Protein argonaute 17; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (876 aa)
AGO1CProtein argonaute 1C; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (1011 aa)
AGO16Protein argonaute 16; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (883 aa)
AGO14Protein argonaute 14; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity); Belongs to the argonaute family. Ago subfamily. (1052 aa)
AGO7Protein argonaute 7; Involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). Regulates shoot apical meristem (SAM) initiation and maintenance and leaf polarization through the trans-acting siRNAS (ta- siRNAs) pathway which probably modulates the expression of the ARF2, ARF3, ARF4, ARF14 and ARF15 genes. (1048 aa)
DCL3BEndoribonuclease Dicer homolog 3b; Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs (By similarity). Belongs to the helicase family. Dicer subfamily. (1637 aa)
AGO1BProtein argonaute 1B; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity); Belongs to the argonaute family. Ago subfamily. (1118 aa)
AGO3Protein argonaute 3; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (1109 aa)
AGO2Protein argonaute 2; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (1034 aa)
AGO12Protein argonaute 12; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (1049 aa)
MEL1Protein argonaute MEL1; Essential for the progression of premeiotic mitosis and meiosis during sporogenesis. Regulates the cell division of premeiotic germ cells, the proper modification of meiotic chromosomes, and the faithful progression of meiosis, probably via small RNA-mediated gene silencing. May be involved in histone H3 'Lys-9' demethylation in the pericentromeric region; Belongs to the argonaute family. Ago subfamily. (1058 aa)
AGO13Protein argonaute 13; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (1192 aa)
DCL1Endoribonuclease Dicer homolog 1; Involved in the RNA silencing pathway. Cleaves double- stranded RNA to produce microRNAs (miRNAs) of 21-24 nucleotides which target the selective destruction of complementary RNAs. Regulates by this way the development of the plant. May not be involved in small interfering RNAs (siRNAs) production. (1883 aa)
AGO4AProtein argonaute 4A; Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity). (904 aa)
Your Current Organism:
Oryza sativa Japonica
NCBI taxonomy Id: 39947
Other names: Japanese rice, Japonica rice, O. sativa Japonica Group, Oryza sativa (japonica cultivar-group), Oryza sativa Japonica Group, Oryza sativa subsp. japonica
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