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CAM2 CAM2 CPK7 CPK7 CAM1-1 CAM1-1 MPK5 MPK5 CIPK15 CIPK15 CML8 CML8 SOS1 SOS1 MPK2 MPK2 CDC6 CDC6 MPK4 MPK4 MPK12 MPK12 CML12 CML12 CYCD3-1 CYCD3-1 APX8 APX8 Q6ER85_ORYSJ Q6ER85_ORYSJ CML9 CML9 CPK6 CPK6 CPK21 CPK21 CIPK23 CIPK23 GST GST HSFB2A HSFB2A CPK12 CPK12 Q7Y140_ORYSJ Q7Y140_ORYSJ CIPK3 CIPK3 CPK3 CPK3 ABI5 ABI5 CML10 CML10 BRI1 BRI1 APX2 APX2 CPK13 CPK13 BBI1 BBI1 CRO1 CRO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAM2Calmodulin-2; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
CPK7Calcium-dependent protein kinase 7; May play a role in signal transduction pathways that involve calcium as a second messenger (By similarity). May be a signaling component in the response to gibberellin and cold stress. (542 aa)
CAM1-1Calmodulin-1; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
MPK5Mitogen-activated protein kinase 5; Involved in disease resistance and abiotic stress tolerance signaling pathways. Acts as a positive regulator of drought, salt and cold tolerance. Negatively modulates pathogenesis-related (PR) gene expression and broad-spectrum disease resistance. Functions downstream of CPK18 in a signaling pathway that represses defense gene expression and negatively regulates resistance to rice blast fungus. Phosphorylated by CPK18 at Thr-14 and Thr-32 and activated independently of MAP kinase kinase (MKK) phosphorylation ; Belongs to the protein kinase superfamil [...] (369 aa)
CIPK15CBL-interacting protein kinase 15; Involved in salt stress tolerance. CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. (434 aa)
CML8Probable calcium-binding protein CML8; Potential calcium sensor. (191 aa)
SOS1Plasma membrane Na+/H+ antiporter, putative, expressed. (1148 aa)
MPK2Mitogen-activated protein kinase 2; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
CDC6Cell division control protein 6 homolog; May be involved in the initiation of DNA replication. (515 aa)
MPK4Mitogen-activated protein kinase 4. (369 aa)
MPK12Mitogen-activated protein kinase 12; May be involved in defense signaling pathway. Phosphorylates EREBP1 transcriptional activator in vitro. Enhances DNA-binding activity of EREBP1 to the GCC box element of pathogenesis-related (PR) gene promoters; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. (580 aa)
CML12Probable calcium-binding protein CML12; Potential calcium sensor. (249 aa)
CYCD3-1Cyclin-D3-1. (342 aa)
APX8Probable L-ascorbate peroxidase 8, chloroplastic; Involved in defense response and tolerance to the bacterial pathogen Xanthomonas oryzae pv. oryzae (Xoo). Plays an important role in hydrogen peroxide removal during infection by Xoo. Involved in response to abiotic stress. Plays a role in hydrogen peroxide removal durings salt stress; Belongs to the peroxidase family. Ascorbate peroxidase subfamily. (478 aa)
Q6ER85_ORYSJcDNA clone:001-118-H05, full insert sequence. (326 aa)
CML9Probable calcium-binding protein CML9; Potential calcium sensor. (155 aa)
CPK6Calcium-dependent protein kinase 6; May play a role in signal transduction pathways that involve calcium as a second messenger; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. (545 aa)
CPK21Calcium-dependent protein kinase 21; May play a role in signal transduction pathways that involve calcium as a second messenger (By similarity). Functions in signal transduction pathways that positively regulate responses to abscisic acid (ABA) and salt stress. (565 aa)
CIPK23CBL-interacting protein kinase 23; CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity); Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. (450 aa)
GSTGlutathione S-transferase, C-terminal domain containing protein, expressed; Belongs to the GST superfamily. (278 aa)
HSFB2AHeat stress transcription factor B-2a; Transcriptional regulator that specifically binds DNA of heat shock promoter elements (HSE). (305 aa)
CPK12Calcium-dependent protein kinase 12; May play a role in signal transduction pathways that involve calcium as a second messenger (By similarity). Functions in signal transduction pathways that positively regulate responses to low- nitrogen. Functions in multiple signaling pathways, positively regulating salt tolerance and negatively modulating rice blast fungus resistance. May promote tolerance to salt stress by negatively regulating NADPH oxidase and positively regulating reactive oxygen species (ROS) scavengers. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. [...] (533 aa)
Q7Y140_ORYSJCalreticulin. (442 aa)
CIPK3CBL-interacting protein kinase 3; CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity). (445 aa)
CPK3Calcium-dependent protein kinase 3; May play a role in signal transduction pathways that involve calcium as a second messenger. (551 aa)
ABI5bZIP transcription factor ABI5 homolog; Transcription factor that possesses transactivation activity in yeast. Involved in abscisic acid (ABA) signaling pathway. Binds to the G-box motif 5'- CACGTG-3' of TRAB1 gene promoter. Involved in the regulation of pollen maturation. May act as negative regulator of salt stress response. Together with PYL5, PP2C30 and SAPK2, is part of an ABA signaling unit that modulates seed germination and early seedling growth. Belongs to the bZIP family. ABI5 subfamily. (388 aa)
CML10Probable calcium-binding protein CML10; Potential calcium sensor. (185 aa)
BRI1Brassinosteroid LRR receptor kinase BRI1; Receptor kinase involved brassinosteroid (BR) signal transduction. Regulates, in response to BR binding, a signaling cascade involved in plant development, promotion of cell elongation and flowering (Probable). Activates BR signaling by targeting and phosphorylating BSK3, a positive regulator of BR signaling. Forms at the plasma membrane a receptor complex with BAK1 which is activated in response to brassinolide. Phosphorylates BAK1. Phosphorylates REM4.1, which reduces REM4.1 binding affinity to BAK1 and allows the formation and subsequent act [...] (1121 aa)
APX2L-ascorbate peroxidase 2, cytosolic; Plays a key role in hydrogen peroxide removal. Plays an important role in plant growth and development by protecting the seedlings from abiotic stresses through scavenging reactive oxygen species. Required for pollen viability ; Belongs to the peroxidase family. Ascorbate peroxidase subfamily. (251 aa)
CPK13Calcium-dependent protein kinase 13; May play a role in signal transduction pathways that involve calcium as a second messenger (By similarity). May function in signal transduction pathways that positively regulate responses to cold, salt and drought stresses ; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. (551 aa)
BBI1cDNA clone:006-205-F10, full insert sequence. (261 aa)
CRO1Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). (424 aa)
Your Current Organism:
Oryza sativa Japonica
NCBI taxonomy Id: 39947
Other names: Japanese rice, Japonica rice, O. sativa Japonica Group, Oryza sativa (japonica cultivar-group), Oryza sativa Japonica Group, Oryza sativa subsp. japonica
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