node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHI | COMT | Q84T92 | Q6ZD89 | Chalcone--flavonone isomerase; Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity). | Flavone 3'-O-methyltransferase 1; Methylates OH residues of flavonoid compounds. Can methylate eriodictyol, luteolin, quercetin and taxifolin. Methylates caffeate to produce ferrulate. Catalyzes the methylation of monolignols, the lignin precursors. Functions cooperatively with CAD2 in the culm internodes for the biosynthesis of monolignols. May be involved in lignin biosynthesis in leaves and roots. Involved in syringyl lignin biosynthesis. Can function as 5-hydroxyconiferaldehyde O- methyltransferase in the biosynthetic pathway to syringyl lignin. Involved in melatonin biosynthesis. [...] | 0.710 |
CHI | CYP75B3 | Q84T92 | Q7G602 | Chalcone--flavonone isomerase; Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity). | Flavonoid 3'-monooxygenase CYP75B3; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes the 3'- hydroxylation of apigenin to generate luteolin (Probable). Belongs to the cytochrome P450 family. | 0.968 |
CHI | CYP75B4 | Q84T92 | Q8LM92 | Chalcone--flavonone isomerase; Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity). | Flavonoid 3'-monooxygenase CYP75B4; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes in vitro 3'-hydroxylation of different flavonoids. Catalyzes the conversion of apigenin to luteolin, naringenin to eriodictyol, and kaempferol to quercetin. Possesses specific 5'-hydroxylase activity toward chrysoeriol (a 3'-methoxylated flavone) and is indispensable for tricin formation. Converts chrysoeriol to selgin, a precursor of tricin, suggesting that chrysoeriol, instead of tricetin, is an intermediate in tricin biosynthesis. | 0.951 |
CHI | CYP93G1 | Q84T92 | Q0JFI2 | Chalcone--flavonone isomerase; Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity). | Cytochrome P450 93G1; Functions as flavone synthase II (FNSII) that catalyzes the direct conversion of flavanones to flavones. In vitro, can desaturate naringenin and eriodictyol to apigenin and luteolin, respectively. Acts as a key branch point enzyme that channels flavanones to the biosynthesis of tricin O-linked conjugates. | 0.954 |
CHI | F3H-3 | Q84T92 | Q7XR84 | Chalcone--flavonone isomerase; Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity). | Flavanone 3-dioxygenase 3; Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R- dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants. Converts (2S)-eriodictyol to (+)- taxifolin and (2S)-naringenin to (+)-(2R/3R)-dihydrokaempferol in vitro ; Belongs to the iron/ascorbate-dependent oxidoreductase family. | 0.433 |
COMT | CHI | Q6ZD89 | Q84T92 | Flavone 3'-O-methyltransferase 1; Methylates OH residues of flavonoid compounds. Can methylate eriodictyol, luteolin, quercetin and taxifolin. Methylates caffeate to produce ferrulate. Catalyzes the methylation of monolignols, the lignin precursors. Functions cooperatively with CAD2 in the culm internodes for the biosynthesis of monolignols. May be involved in lignin biosynthesis in leaves and roots. Involved in syringyl lignin biosynthesis. Can function as 5-hydroxyconiferaldehyde O- methyltransferase in the biosynthetic pathway to syringyl lignin. Involved in melatonin biosynthesis. [...] | Chalcone--flavonone isomerase; Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity). | 0.710 |
COMT | ROMT-15 | Q6ZD89 | Q9XGP7 | Flavone 3'-O-methyltransferase 1; Methylates OH residues of flavonoid compounds. Can methylate eriodictyol, luteolin, quercetin and taxifolin. Methylates caffeate to produce ferrulate. Catalyzes the methylation of monolignols, the lignin precursors. Functions cooperatively with CAD2 in the culm internodes for the biosynthesis of monolignols. May be involved in lignin biosynthesis in leaves and roots. Involved in syringyl lignin biosynthesis. Can function as 5-hydroxyconiferaldehyde O- methyltransferase in the biosynthetic pathway to syringyl lignin. Involved in melatonin biosynthesis. [...] | Tricin synthase 1; Catalyzes the stepwise methylation of tricetin to its 3'- mono- and 3',5'-dimethyl ethers. No 3',4',5'-trimethylated ester derivatives are produced. Can use caffeoyl-CoA, 5-hydroxyferulic acid, luteolin, tricetin, quercetin, myrcetin and 7,8-dihydroxyflavone as substrates, but not naringenin, apigenin or kaempferol. The 2,3-double bond and the O-dihydroxyl group of the substrate are both required for catalytic activity of the enzyme; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily. | 0.447 |
COMT | ROMT-17 | Q6ZD89 | Q7F8T6 | Flavone 3'-O-methyltransferase 1; Methylates OH residues of flavonoid compounds. Can methylate eriodictyol, luteolin, quercetin and taxifolin. Methylates caffeate to produce ferrulate. Catalyzes the methylation of monolignols, the lignin precursors. Functions cooperatively with CAD2 in the culm internodes for the biosynthesis of monolignols. May be involved in lignin biosynthesis in leaves and roots. Involved in syringyl lignin biosynthesis. Can function as 5-hydroxyconiferaldehyde O- methyltransferase in the biosynthetic pathway to syringyl lignin. Involved in melatonin biosynthesis. [...] | Tricin synthase 2; Catalyzes the stepwise methylation of tricetin to its 3'- mono- and 3',5'-dimethyl ethers. No 3',4',5'-trimethylated ester derivatives are produced. Can use caffeoyl CoA, 5-hydroxyferulic acid, luteolin, tricetin, quercetin, myrcetin and 7,8-dihydroxyflavone as substrates, but not naringenin, apigenin or kaempferol. The 2,3-double bond and the O-dihydroxyl group of the substrate are both required for catalytic activity of the enzyme; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily. | 0.433 |
CYP72A18 | CYP75B3 | Q9FDZ1 | Q7G602 | cDNA clone:J033048K24, full insert sequence; Belongs to the cytochrome P450 family. | Flavonoid 3'-monooxygenase CYP75B3; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes the 3'- hydroxylation of apigenin to generate luteolin (Probable). Belongs to the cytochrome P450 family. | 0.522 |
CYP72A18 | CYP75B4 | Q9FDZ1 | Q8LM92 | cDNA clone:J033048K24, full insert sequence; Belongs to the cytochrome P450 family. | Flavonoid 3'-monooxygenase CYP75B4; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes in vitro 3'-hydroxylation of different flavonoids. Catalyzes the conversion of apigenin to luteolin, naringenin to eriodictyol, and kaempferol to quercetin. Possesses specific 5'-hydroxylase activity toward chrysoeriol (a 3'-methoxylated flavone) and is indispensable for tricin formation. Converts chrysoeriol to selgin, a precursor of tricin, suggesting that chrysoeriol, instead of tricetin, is an intermediate in tricin biosynthesis. | 0.488 |
CYP72A18 | CYP93G1 | Q9FDZ1 | Q0JFI2 | cDNA clone:J033048K24, full insert sequence; Belongs to the cytochrome P450 family. | Cytochrome P450 93G1; Functions as flavone synthase II (FNSII) that catalyzes the direct conversion of flavanones to flavones. In vitro, can desaturate naringenin and eriodictyol to apigenin and luteolin, respectively. Acts as a key branch point enzyme that channels flavanones to the biosynthesis of tricin O-linked conjugates. | 0.519 |
CYP72A32 | CYP75B3 | Q8S1C7 | Q7G602 | Cytochrome P450 monooxygenase; Belongs to the cytochrome P450 family. | Flavonoid 3'-monooxygenase CYP75B3; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes the 3'- hydroxylation of apigenin to generate luteolin (Probable). Belongs to the cytochrome P450 family. | 0.479 |
CYP72A32 | CYP75B4 | Q8S1C7 | Q8LM92 | Cytochrome P450 monooxygenase; Belongs to the cytochrome P450 family. | Flavonoid 3'-monooxygenase CYP75B4; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes in vitro 3'-hydroxylation of different flavonoids. Catalyzes the conversion of apigenin to luteolin, naringenin to eriodictyol, and kaempferol to quercetin. Possesses specific 5'-hydroxylase activity toward chrysoeriol (a 3'-methoxylated flavone) and is indispensable for tricin formation. Converts chrysoeriol to selgin, a precursor of tricin, suggesting that chrysoeriol, instead of tricetin, is an intermediate in tricin biosynthesis. | 0.437 |
CYP72A32 | CYP93G1 | Q8S1C7 | Q0JFI2 | Cytochrome P450 monooxygenase; Belongs to the cytochrome P450 family. | Cytochrome P450 93G1; Functions as flavone synthase II (FNSII) that catalyzes the direct conversion of flavanones to flavones. In vitro, can desaturate naringenin and eriodictyol to apigenin and luteolin, respectively. Acts as a key branch point enzyme that channels flavanones to the biosynthesis of tricin O-linked conjugates. | 0.473 |
CYP75B3 | CHI | Q7G602 | Q84T92 | Flavonoid 3'-monooxygenase CYP75B3; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes the 3'- hydroxylation of apigenin to generate luteolin (Probable). Belongs to the cytochrome P450 family. | Chalcone--flavonone isomerase; Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity). | 0.968 |
CYP75B3 | CYP72A18 | Q7G602 | Q9FDZ1 | Flavonoid 3'-monooxygenase CYP75B3; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes the 3'- hydroxylation of apigenin to generate luteolin (Probable). Belongs to the cytochrome P450 family. | cDNA clone:J033048K24, full insert sequence; Belongs to the cytochrome P450 family. | 0.522 |
CYP75B3 | CYP72A32 | Q7G602 | Q8S1C7 | Flavonoid 3'-monooxygenase CYP75B3; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes the 3'- hydroxylation of apigenin to generate luteolin (Probable). Belongs to the cytochrome P450 family. | Cytochrome P450 monooxygenase; Belongs to the cytochrome P450 family. | 0.479 |
CYP75B3 | CYP75B4 | Q7G602 | Q8LM92 | Flavonoid 3'-monooxygenase CYP75B3; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes the 3'- hydroxylation of apigenin to generate luteolin (Probable). Belongs to the cytochrome P450 family. | Flavonoid 3'-monooxygenase CYP75B4; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes in vitro 3'-hydroxylation of different flavonoids. Catalyzes the conversion of apigenin to luteolin, naringenin to eriodictyol, and kaempferol to quercetin. Possesses specific 5'-hydroxylase activity toward chrysoeriol (a 3'-methoxylated flavone) and is indispensable for tricin formation. Converts chrysoeriol to selgin, a precursor of tricin, suggesting that chrysoeriol, instead of tricetin, is an intermediate in tricin biosynthesis. | 0.941 |
CYP75B3 | CYP93G1 | Q7G602 | Q0JFI2 | Flavonoid 3'-monooxygenase CYP75B3; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes the 3'- hydroxylation of apigenin to generate luteolin (Probable). Belongs to the cytochrome P450 family. | Cytochrome P450 93G1; Functions as flavone synthase II (FNSII) that catalyzes the direct conversion of flavanones to flavones. In vitro, can desaturate naringenin and eriodictyol to apigenin and luteolin, respectively. Acts as a key branch point enzyme that channels flavanones to the biosynthesis of tricin O-linked conjugates. | 0.948 |
CYP75B3 | F3H-3 | Q7G602 | Q7XR84 | Flavonoid 3'-monooxygenase CYP75B3; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes the 3'- hydroxylation of apigenin to generate luteolin (Probable). Belongs to the cytochrome P450 family. | Flavanone 3-dioxygenase 3; Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R- dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants. Converts (2S)-eriodictyol to (+)- taxifolin and (2S)-naringenin to (+)-(2R/3R)-dihydrokaempferol in vitro ; Belongs to the iron/ascorbate-dependent oxidoreductase family. | 0.749 |