STRINGSTRING
trpA trpA trpB trpB SDH10371.1 SDH10371.1 SDH10401.1 SDH10401.1 SDH10429.1 SDH10429.1 SDH10456.1 SDH10456.1 hisI hisI hisF hisF hisG hisG SDH10562.1 SDH10562.1 SDH10626.1 SDH10626.1 fmt fmt priA priA metK metK SDH10730.1 SDH10730.1 gmk gmk SDH10809.1 SDH10809.1 carB carB carA carA SDH10893.1 SDH10893.1 pyrC pyrC pyrB pyrB pyrR pyrR nusB nusB aroQ aroQ aroB aroB aroK aroK aroC aroC SDH11165.1 SDH11165.1 pepA pepA panB panB SDH14610.1 SDH14610.1 leuA leuA SDH16055.1 SDH16055.1 pyrD pyrD hisD hisD SDH18186.1 SDH18186.1 SDH20692.1 SDH20692.1 hisA hisA SDH21850.1 SDH21850.1 hisB hisB hisC hisC SDH21982.1 SDH21982.1 SDH22007.1 SDH22007.1 dapF dapF dapA dapA SDH22680.1 SDH22680.1 SDH22910.1 SDH22910.1 SDH23173.1 SDH23173.1 SDH23182.1 SDH23182.1 SDH23213.1 SDH23213.1 truB truB SDH23268.1 SDH23268.1 SDH24816.1 SDH24816.1 SDH24843.1 SDH24843.1 thrB thrB SDH25383.1 SDH25383.1 SDH25415.1 SDH25415.1 lysA lysA coaD coaD SDH28290.1 SDH28290.1 folD folD purU purU purH purH SDH31027.1 SDH31027.1 guaA guaA SDH32498.1 SDH32498.1 guaB guaB coaA coaA SDH35314.1 SDH35314.1 panC panC SDH39269.1 SDH39269.1 SDH39300.1 SDH39300.1 folE folE SDH39398.1 SDH39398.1 tilS tilS SDH40041.1 SDH40041.1 SDH45348.1 SDH45348.1 SDH52137.1 SDH52137.1 SDH52771.1 SDH52771.1 SDH53074.1 SDH53074.1 SDH56050.1 SDH56050.1 SDH56089.1 SDH56089.1 SDH56530.1 SDH56530.1 SDH59066.1 SDH59066.1 SDH63036.1 SDH63036.1 SDH63293.1 SDH63293.1 pyrE pyrE purA purA apt apt SDH68409.1 SDH68409.1 purL purL purQ purQ purS purS purC purC purD purD SDH69137.1 SDH69137.1 purF purF purM purM SDH69709.1 SDH69709.1 SDH69745.1 SDH69745.1 SDH69773.1 SDH69773.1 SDH70808.1 SDH70808.1 SDH71699.1 SDH71699.1 SDH72804.1 SDH72804.1 SDH75801.1 SDH75801.1 SDH76886.1 SDH76886.1 SDH76913.1 SDH76913.1 SDH77384.1 SDH77384.1 asd asd ribH ribH ribA ribA SDH78656.1 SDH78656.1 SDH78682.1 SDH78682.1 purK purK purE purE ahcY ahcY SDH84290.1 SDH84290.1 SDH84778.1 SDH84778.1 ilvD ilvD SDH84919.1 SDH84919.1 SDH84949.1 SDH84949.1 ilvC ilvC leuB leuB SDH85677.1 SDH85677.1 SDH87590.1 SDH87590.1 leuC leuC leuD leuD SDH88921.1 SDH88921.1 SDH89805.1 SDH89805.1 SDH89865.1 SDH89865.1 dapD dapD SDH90045.1 SDH90045.1 SDH91230.1 SDH91230.1 aroA aroA SDH93013.1 SDH93013.1 metXA metXA SDH93137.1 SDH93137.1 SDH96578.1 SDH96578.1 SDH98090.1 SDH98090.1 SDH98202.1 SDH98202.1 trpD trpD SDI01616.1 SDI01616.1 SDI02997.1 SDI02997.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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gene neighborhood
gene fusions
gene co-occurrence
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trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (265 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (403 aa)
SDH10371.1Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (259 aa)
SDH10401.1Hypothetical protein. (81 aa)
SDH10429.1Tryptophan-associated transmembrane protein (Trp_oprn_chp). (189 aa)
SDH10456.1Anthranilate synthase, component I. (506 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (109 aa)
hisFImidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa)
hisGATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (279 aa)
SDH10562.1phosphoribosyl-ATP pyrophosphatase; Belongs to the PRA-PH family. (86 aa)
SDH10626.116S rRNA (cytosine967-C5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (474 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (303 aa)
priAReplication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (630 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (396 aa)
SDH10730.1Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (398 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (285 aa)
SDH10809.1Orotidine-5'-phosphate decarboxylase. (270 aa)
carBCarbamoyl-phosphate synthase large subunit. (1091 aa)
carACarbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (374 aa)
SDH10893.1Hypothetical protein. (165 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (428 aa)
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (312 aa)
pyrRPyrimidine operon attenuation protein / uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (182 aa)
nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (140 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (354 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (165 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (395 aa)
SDH11165.1Shikimate dehydrogenase. (258 aa)
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (490 aa)
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (285 aa)
SDH14610.1Hypothetical protein. (154 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (589 aa)
SDH16055.1Anthranilate synthase component 1. (430 aa)
pyrDDihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (339 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa)
SDH18186.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Belongs to the class-II DAHP synthase family. (454 aa)
SDH20692.1Prephenate dehydrogenase. (351 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (249 aa)
SDH21850.1Imidazole glycerol phosphate synthase subunit hisH. (201 aa)
hisBImidazoleglycerol-phosphate dehydratase. (198 aa)
hisCHistidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (362 aa)
SDH21982.1Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (750 aa)
SDH22007.1Methylenetetrahydrofolate reductase (NADPH); Belongs to the methylenetetrahydrofolate reductase family. (302 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (282 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (325 aa)
SDH22680.1Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (234 aa)
SDH22910.1Aspartate ammonia-lyase. (503 aa)
SDH23173.1Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. (316 aa)
SDH23182.1Hypothetical protein. (138 aa)
SDH23213.1Hypothetical protein. (122 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (302 aa)
SDH23268.1Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (325 aa)
SDH24816.1Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (309 aa)
SDH24843.1Serine O-acetyltransferase. (176 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (305 aa)
SDH25383.1L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (356 aa)
SDH25415.1Homoserine dehydrogenase. (433 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (448 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa)
SDH28290.1O-acetylhomoserine sulfhydrylase. (432 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (282 aa)
purHIMP cyclohydrolase. (546 aa)
SDH31027.1Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase. (186 aa)
guaAGMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. (523 aa)
SDH32498.1IMP dehydrogenase. (371 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa)
coaAPantothenate kinase. (309 aa)
SDH35314.1Formiminoglutamase; Belongs to the arginase family. (296 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (282 aa)
SDH39269.12-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. (168 aa)
SDH39300.1Dihydroneopterin aldolase/dihydropteroate synthase,TIGR01496; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (391 aa)
folEGTP cyclohydrolase I. (189 aa)
SDH39398.1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (188 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (331 aa)
SDH40041.1Aspartate aminotransferase. (380 aa)
SDH45348.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (400 aa)
SDH52137.1Cystathione beta-lyase. (390 aa)
SDH52771.1Histidinol-phosphate aminotransferase. (352 aa)
SDH53074.1Adenylosuccinate lyase. (459 aa)
SDH56050.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (310 aa)
SDH56089.1Pyrimidine reductase, riboflavin biosynthesis. (246 aa)
SDH56530.1Anthranilate synthase, component II. (213 aa)
SDH59066.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (335 aa)
SDH63036.1Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase. (362 aa)
SDH63293.1Acetolactate synthase large subunit; Belongs to the TPP enzyme family. (560 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (183 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (174 aa)
SDH68409.1Chorismate mutase. (96 aa)
purLPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (764 aa)
purQPhosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (230 aa)
purSPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (84 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (296 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (423 aa)
SDH69137.1Nucleobase:cation symporter-2, NCS2 family. (440 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (484 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (378 aa)
SDH69709.1L-serine ammonia-lyase. (495 aa)
SDH69745.1Protein of unknown function. (66 aa)
SDH69773.1Glutamate carboxypeptidase. (374 aa)
SDH70808.1Prephenate dehydratase. (306 aa)
SDH71699.1O-acetylhomoserine sulfhydrylase. (436 aa)
SDH72804.1GMP synthase (glutamine-hydrolysing). (225 aa)
SDH75801.1Aspartate aminotransferase. (397 aa)
SDH76886.1Cystathionine beta-synthase. (456 aa)
SDH76913.1Cystathionine gamma-lyase. (379 aa)
SDH77384.1Aspartate kinase; Belongs to the aspartokinase family. (423 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (347 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (154 aa)
ribAGTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. (421 aa)
SDH78656.1Riboflavin synthase alpha chain. (213 aa)
SDH78682.1Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (362 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (372 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (179 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (481 aa)
SDH84290.1L-threonine ammonia-lyase. (415 aa)
SDH84778.1Alanine-synthesizing transaminase. (407 aa)
ilvDDihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (563 aa)
SDH84919.1Acetolactate synthase, large subunit. (595 aa)
SDH84949.1Acetolactate synthase, small subunit. (169 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (341 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (348 aa)
SDH85677.1Branched chain amino acid aminotransferase apoenzyme. (365 aa)
SDH87590.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (399 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (479 aa)
leuD3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (202 aa)
SDH88921.1Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (351 aa)
SDH89805.1Succinyldiaminopimelate transaminase. (361 aa)
SDH89865.1Putative MFS transporter, AGZA family, xanthine/uracil permease. (482 aa)
dapD2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (312 aa)
SDH90045.1Succinyldiaminopimelate desuccinylase. (362 aa)
SDH91230.1Succinyldiaminopimelate aminotransferase apoenzyme. (402 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (436 aa)
SDH93013.1IMP dehydrogenase. (477 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (398 aa)
SDH93137.1O-acetylhomoserine sulfhydrylase. (435 aa)
SDH96578.1Aminopeptidase N. (847 aa)
SDH98090.14-amino-4-deoxychorismate lyase. (283 aa)
SDH98202.1Dihydrofolate synthase / folylpolyglutamate synthase. (525 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (355 aa)
SDI01616.1Cystathionine gamma-synthase. (352 aa)
SDI02997.1Phosphoserine phosphatase. (217 aa)
Your Current Organism:
Agrococcus jejuensis
NCBI taxonomy Id: 399736
Other names: A. jejuensis, Agrococcus jejuensis Lee 2008, DSM 22002, JCM 14256, KCTC 19198, strain SSW1-48
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