STRINGSTRING
Pmen_3114 Pmen_3114 Pmen_3124 Pmen_3124 Pmen_3228 Pmen_3228 Pmen_3280 Pmen_3280 xseA xseA Pmen_3561 Pmen_3561 rhlB rhlB pnp pnp Pmen_3655 Pmen_3655 Pmen_3705 Pmen_3705 Pmen_3706 Pmen_3706 Pmen_3728 Pmen_3728 Pmen_3834 Pmen_3834 xseB xseB Pmen_4158 Pmen_4158 Pmen_4210 Pmen_4210 rppH rppH Pmen_4227 Pmen_4227 Pmen_4229 Pmen_4229 Pmen_4230 Pmen_4230 Pmen_4262 Pmen_4262 Pmen_4263 Pmen_4263 dut dut rph rph Pmen_4387 Pmen_4387 Pmen_4448 Pmen_4448 Pmen_4481 Pmen_4481 Pmen_4482 Pmen_4482 Pmen_4483 Pmen_4483 Pmen_4507 Pmen_4507 Pmen_1038 Pmen_1038 Pmen_0972 Pmen_0972 Pmen_0933 Pmen_0933 Pmen_0779 Pmen_0779 Pmen_0764 Pmen_0764 Pmen_1340 Pmen_1340 Pmen_0752 Pmen_0752 Pmen_0741 Pmen_0741 Pmen_0672 Pmen_0672 Pmen_0603 Pmen_0603 Pmen_0479 Pmen_0479 Pmen_0474 Pmen_0474 allA allA Pmen_0229 Pmen_0229 Pmen_0226 Pmen_0226 Pmen_1502 Pmen_1502 Pmen_1556 Pmen_1556 rne rne Pmen_1696 Pmen_1696 Pmen_1697 Pmen_1697 Pmen_1698 Pmen_1698 Pmen_1699 Pmen_1699 Pmen_1736 Pmen_1736 mtaD mtaD Pmen_2005 Pmen_2005 Pmen_2015 Pmen_2015 rnhA rnhA nudC nudC Pmen_2136 Pmen_2136 deaD deaD Pmen_2157 Pmen_2157 Pmen_2198 Pmen_2198 Pmen_2199 Pmen_2199 Pmen_2200 Pmen_2200 Pmen_2346 Pmen_2346 Pmen_2347 Pmen_2347 Pmen_2441 Pmen_2441 Pmen_2490 Pmen_2490 Pmen_2624 Pmen_2624 Pmen_2664 Pmen_2664 Pmen_2680 Pmen_2680 Pmen_2705 Pmen_2705 Pmen_2753 Pmen_2753 Pmen_2754 Pmen_2754 allA-2 allA-2 csrA csrA Pmen_3004 Pmen_3004 surE surE rnhB rnhB Pmen_3111 Pmen_3111 Pmen_3112 Pmen_3112 Pmen_1293 Pmen_1293 Pmen_1140 Pmen_1140 Pmen_1139 Pmen_1139 Pmen_1120 Pmen_1120 leuA leuA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pmen_3114Aromatic amino acid aminotransferase apoenzyme; PFAM: aminotransferase, class I and II. (398 aa)
Pmen_3124PFAM: alpha/beta hydrolase fold. (247 aa)
Pmen_3228TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
Pmen_3280PFAM: alpha/beta hydrolase fold. (302 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (476 aa)
Pmen_3561Carboxylesterase; PFAM: phospholipase/Carboxylesterase. (219 aa)
rhlBDEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (482 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (725 aa)
Pmen_3655PFAM: alpha/beta hydrolase fold. (312 aa)
Pmen_3705Hydroxydechloroatrazine ethylaminohydrolase; PFAM: amidohydrolase; Amidohydrolase 3. (451 aa)
Pmen_3706Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (315 aa)
Pmen_3728PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; Belongs to the DEAD box helicase family. (447 aa)
Pmen_3834PFAM: amidohydrolase; Amidohydrolase 3. (409 aa)
xseBExodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (132 aa)
Pmen_4158Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (198 aa)
Pmen_4210PFAM: glycerophosphoryl diester phosphodiesterase. (383 aa)
rppHNUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (159 aa)
Pmen_4227PFAM: SdiA-regulated domain protein. (303 aa)
Pmen_4229PFAM: SdiA-regulated domain protein. (317 aa)
Pmen_4230PFAM: fumarylacetoacetate (FAA) hydrolase. (232 aa)
Pmen_4262Hypothetical protein. (152 aa)
Pmen_4263PFAM: ribonuclease H. (162 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (151 aa)
rphRNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (239 aa)
Pmen_4387PFAM: YicC N-terminal domain protein; domain of unknown function DUF1732. (287 aa)
Pmen_4448PFAM: Antibiotic biosynthesis monooxygenase. (106 aa)
Pmen_4481PFAM: protein of unknown function DUF182. (395 aa)
Pmen_4482PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding. (747 aa)
Pmen_4483PFAM: ferredoxin; [2Fe-2S]-binding domain protein. (152 aa)
Pmen_4507PFAM: Haem oxygenase. (196 aa)
Pmen_1038PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; Belongs to the 5'-nucleotidase family. (638 aa)
Pmen_0972PFAM: NADH:flavin oxidoreductase/NADH oxidase. (369 aa)
Pmen_0933PFAM: Glutathione S-transferase, N-terminal domain. (210 aa)
Pmen_0779PFAM: protein of unknown function DUF1631. (766 aa)
Pmen_0764PFAM: protein of unknown function DUF1631. (781 aa)
Pmen_13405-carboxymethyl-2-hydroxymuconate isomerase-like protein. (117 aa)
Pmen_0752PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein. (258 aa)
Pmen_0741Hypothetical protein. (101 aa)
Pmen_0672PFAM: alpha/beta hydrolase fold. (315 aa)
Pmen_0603Hypothetical protein. (327 aa)
Pmen_0479PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; Belongs to the DEAD box helicase family. (458 aa)
Pmen_0474PFAM: intradiol ring-cleavage dioxygenase. (247 aa)
allAUreidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source. (173 aa)
Pmen_0229Putative metal dependent phosphohydrolase; PFAM: regulatory protein, LuxR. (474 aa)
Pmen_0226PFAM: Glutathione S-transferase, N-terminal domain. (201 aa)
Pmen_1502PFAM: Antibiotic biosynthesis monooxygenase. (114 aa)
Pmen_1556PFAM: DoxX family protein. (199 aa)
rneRNAse E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1012 aa)
Pmen_1696TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. (360 aa)
Pmen_1697PFAM: homogentisate 1,2-dioxygenase. (379 aa)
Pmen_1698PFAM: fumarylacetoacetate (FAA) hydrolase. (326 aa)
Pmen_1699TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain. (216 aa)
Pmen_1736TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase. (276 aa)
mtaDAmidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. (439 aa)
Pmen_2005PFAM: NADH:flavin oxidoreductase/NADH oxidase. (359 aa)
Pmen_2015PFAM: nitroreductase. (216 aa)
rnhARNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (150 aa)
nudCPFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. NudC subfamily. (273 aa)
Pmen_2136Hypothetical protein. (157 aa)
deaDDEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (560 aa)
Pmen_2157Hypothetical protein. (97 aa)
Pmen_2198PFAM: ferredoxin; [2Fe-2S]-binding domain protein. (177 aa)
Pmen_2199PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding. (730 aa)
Pmen_2200PFAM: protein of unknown function DUF182. (382 aa)
Pmen_2346PFAM: molybdopterin dehydrogenase, FAD-binding. (329 aa)
Pmen_2347PFAM: ferredoxin; [2Fe-2S]-binding domain protein. (169 aa)
Pmen_2441PFAM: DoxX family protein. (144 aa)
Pmen_2490PFAM: dienelactone hydrolase. (262 aa)
Pmen_2624PFAM: DSBA oxidoreductase. (197 aa)
Pmen_2664PFAM: Amidohydrolase 3. (660 aa)
Pmen_2680PFAM: short-chain dehydrogenase/reductase SDR; KR. (253 aa)
Pmen_2705PFAM: alpha/beta hydrolase fold. (309 aa)
Pmen_2753Molybdenum cofactor sulfurylase; PFAM: protein of unknown function DUF182. (276 aa)
Pmen_2754Amidohydrolase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (433 aa)
allA-2Ureidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source. (167 aa)
csrACarbon storage regulator, CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (61 aa)
Pmen_3004TIGRFAM: putative deoxyguanosinetriphosphate triphosphohydrolase; SMART: metal-dependent phosphohydrolase, HD region. (443 aa)
surE3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (249 aa)
rnhBRibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (208 aa)
Pmen_3111Transcriptional regulator, TyrR; PFAM: sigma-54 factor, interaction domain-containing protein; amino acid-binding ACT domain protein; SMART: PAS domain containing protein; AAA ATPase. (517 aa)
Pmen_3112TIGRFAM: phenylalanine-4-hydroxylase; PFAM: aromatic amino acid hydroxylase. (261 aa)
Pmen_1293PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein. (275 aa)
Pmen_1140TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase. (232 aa)
Pmen_1139TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase. (218 aa)
Pmen_1120PFAM: NADH:flavin oxidoreductase/NADH oxidase. (349 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (515 aa)
Your Current Organism:
Pseudomonas mendocina ymp
NCBI taxonomy Id: 399739
Other names: P. mendocina ymp, Pseudomonas mendocina str. ymp, Pseudomonas mendocina strain ymp
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.