STRINGSTRING
Pmen_4245 Pmen_4245 aroE aroE Pmen_0202 Pmen_0202 Pmen_0203 Pmen_0203 cysQ cysQ Pmen_0459 Pmen_0459 Pmen_0474 Pmen_0474 thiC thiC Pmen_0791 Pmen_0791 Pmen_0804 Pmen_0804 Pmen_0964 Pmen_0964 Pmen_1051 Pmen_1051 Pmen_1143 Pmen_1143 Pmen_1395 Pmen_1395 pdxH pdxH pdxJ pdxJ Pmen_1558 Pmen_1558 Pmen_1698 Pmen_1698 serC serC pdxB pdxB Pmen_1943 Pmen_1943 Pmen_1944 Pmen_1944 Pmen_1957 Pmen_1957 Pmen_1958 Pmen_1958 Pmen_1961 Pmen_1961 Pmen_1963 Pmen_1963 gloB gloB Pmen_2283 Pmen_2283 Pmen_2300 Pmen_2300 Pmen_2450 Pmen_2450 Pmen_2592 Pmen_2592 Pmen_2642 Pmen_2642 Pmen_2682 Pmen_2682 Pmen_2683 Pmen_2683 folE folE Pmen_2794 Pmen_2794 Pmen_2929 Pmen_2929 Pmen_3028 Pmen_3028 uppS uppS Pmen_3100 Pmen_3100 Pmen_3113 Pmen_3113 Pmen_3120 Pmen_3120 Pmen_3122 Pmen_3122 Pmen_3148 Pmen_3148 folE-2 folE-2 Pmen_3290 Pmen_3290 Pmen_3320 Pmen_3320 glpK glpK Pmen_3348 Pmen_3348 Pmen_3515 Pmen_3515 lldD lldD dld dld mqo-2 mqo-2 Pmen_3720 Pmen_3720 Pmen_3772 Pmen_3772 thiE thiE Pmen_4472 Pmen_4472 dxs dxs thiL thiL Pmen_3936 Pmen_3936 gph gph pdxA pdxA glpE glpE Pmen_4126 Pmen_4126 thiI thiI thiG thiG Pmen_4168 Pmen_4168 Pmen_4207 Pmen_4207 Pmen_4230 Pmen_4230 Pmen_4231 Pmen_4231
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pmen_4245PFAM: Rhodanese domain protein. (137 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (273 aa)
Pmen_0202PFAM: FAD linked oxidase domain protein. (351 aa)
Pmen_0203TIGRFAM: glycolate oxidase, subunit GlcD; PFAM: FAD linked oxidase domain protein. (499 aa)
cysQ3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (272 aa)
Pmen_0459D-erythrose-4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate. (355 aa)
Pmen_0474PFAM: intradiol ring-cleavage dioxygenase. (247 aa)
thiCHydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (627 aa)
Pmen_0791Quinoprotein glucose dehydrogenase; PFAM: Pyrrolo-quinoline quinone. (806 aa)
Pmen_0804PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase. (389 aa)
Pmen_0964TIGRFAM: glycine oxidase ThiO; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase. (361 aa)
Pmen_1051Hypothetical protein. (187 aa)
Pmen_1143PFAM: ThiJ/PfpI domain protein. (284 aa)
Pmen_1395Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (130 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (215 aa)
pdxJPyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (248 aa)
Pmen_1558PFAM: FAD linked oxidase domain protein. (531 aa)
Pmen_1698PFAM: fumarylacetoacetate (FAA) hydrolase. (326 aa)
serCPhosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa)
pdxB4-phosphoerythronate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (376 aa)
Pmen_1943Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver. (221 aa)
Pmen_1944Hypothetical protein. (191 aa)
Pmen_1957PFAM: Pyrrolo-quinoline quinone. (620 aa)
Pmen_1958Hypothetical protein. (139 aa)
Pmen_1961PFAM: beta-lactamase domain protein. (309 aa)
Pmen_1963PFAM: Pyrrolo-quinoline quinone. (591 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (257 aa)
Pmen_2283PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (422 aa)
Pmen_2300Glutathione-independent formaldehyde dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (388 aa)
Pmen_2450PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5. (305 aa)
Pmen_2592PFAM: Rhodanese domain protein. (119 aa)
Pmen_2642PFAM: Rhodanese domain protein. (145 aa)
Pmen_2682PFAM: Ethanolamine ammonia lyase large subunit. (464 aa)
Pmen_2683PFAM: Ethanolamine ammonia-lyase light chain; Belongs to the EutC family. (254 aa)
folEPFAM: GTP cyclohydrolase I. (181 aa)
Pmen_2794SMART: Rhodanese domain protein. (147 aa)
Pmen_2929PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5. (319 aa)
Pmen_3028PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (370 aa)
uppSUndecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (248 aa)
Pmen_3100PFAM: beta-lactamase domain protein. (287 aa)
Pmen_3113PFAM: transcriptional coactivator/pterin dehydratase. (117 aa)
Pmen_3120Glucosyl-glycerol phosphate synthase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; glucosylglycerol-phosphate synthase; PFAM: glycosyl transferase, family 20; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase, type 3. (752 aa)
Pmen_3122PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3-methyltransferase. (139 aa)
Pmen_3148PFAM: 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (234 aa)
folE-2PFAM: GTP cyclohydrolase I. (186 aa)
Pmen_3290PFAM: dihydroneopterin aldolase. (123 aa)
Pmen_3320PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase. (347 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (495 aa)
Pmen_3348Homodimeric glycerol 3-phosphate dehydrogenase (quinone); PFAM: FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (509 aa)
Pmen_3515PFAM: inositol monophosphatase. (271 aa)
lldDFMN-dependent alpha-hydroxy acid dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain. (379 aa)
dldD-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (590 aa)
mqo-2TIGRFAM: malate--quinone oxidoreductase; PFAM: FAD dependent oxidoreductase; Malate:quinone-oxidoreductase. (498 aa)
Pmen_3720Hypothetical protein. (540 aa)
Pmen_3772PFAM: Phosphomethylpyrimidine kinase type-1. (265 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (209 aa)
Pmen_4472Fructuronate reductase; PFAM: Mannitol dehydrogenase, C-terminal domain; Mannitol dehydrogenase rossman, N-terminal domain. (491 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (631 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (317 aa)
Pmen_3936PFAM: alanine racemase domain protein. (420 aa)
gphPhosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (226 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (337 aa)
glpEThiosulfate sulfurtransferase; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. (109 aa)
Pmen_4126Glutathione-independent formaldehyde dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (399 aa)
thiI[ThiS-adenylate] sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (484 aa)
thiGThiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (264 aa)
Pmen_4168TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. (66 aa)
Pmen_4207TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. (175 aa)
Pmen_4230PFAM: fumarylacetoacetate (FAA) hydrolase. (232 aa)
Pmen_4231PFAM: FAD linked oxidase domain protein. (463 aa)
Your Current Organism:
Pseudomonas mendocina ymp
NCBI taxonomy Id: 399739
Other names: P. mendocina ymp, Pseudomonas mendocina str. ymp, Pseudomonas mendocina strain ymp
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