STRINGSTRING
Spro_0154 Spro_0154 Spro_0511 Spro_0511 Spro_0615 Spro_0615 Spro_1085 Spro_1085 cyoE cyoE Spro_1087 Spro_1087 Spro_1088 Spro_1088 Spro_1089 Spro_1089 Spro_1090 Spro_1090 Spro_1525 Spro_1525 acpP-2 acpP-2 Spro_2422 Spro_2422 Spro_2423 Spro_2423 Spro_2424 Spro_2424 Spro_2425 Spro_2425 Spro_2426 Spro_2426 Spro_2427 Spro_2427 Spro_2428 Spro_2428 Spro_2429 Spro_2429 Spro_2430 Spro_2430 Spro_2431 Spro_2431 Spro_2432 Spro_2432 Spro_2433 Spro_2433 Spro_2434 Spro_2434 hypA hypA Spro_2436 Spro_2436 Spro_2437 Spro_2437 Spro_2438 Spro_2438 Spro_2439 Spro_2439 Spro_2440 Spro_2440 nuoN nuoN Spro_3297 Spro_3297 Spro_3298 Spro_3298 nuoK nuoK Spro_3300 Spro_3300 nuoI nuoI nuoH nuoH Spro_3303 Spro_3303 Spro_3304 Spro_3304 Spro_3305 Spro_3305 nuoC nuoC nuoB nuoB nuoA nuoA Spro_3664 Spro_3664
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Spro_0154PFAM: peptidase M16 domain protein; KEGG: yen:YE4066 putative insulinase family protease. (497 aa)
Spro_0511KEGG: ypi:YpsIP31758_3569 hypothetical protein. (212 aa)
Spro_0615PFAM: alpha/beta hydrolase fold; KEGG: sco:SCO6966 lipase. (268 aa)
Spro_1085PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: yen:YE3146 putative transporter. (454 aa)
cyoEProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (296 aa)
Spro_1087TIGRFAM: Cytochrome o ubiquinol oxidase subunit IV; PFAM: cytochrome C oxidase subunit IV; KEGG: ypi:YpsIP31758_3101 cytochrome o ubiquinol oxidase, subunit IV. (112 aa)
Spro_1088TIGRFAM: Cytochrome o ubiquinol oxidase subunit III; PFAM: cytochrome c oxidase subunit III; KEGG: yen:YE3143 cytochrome o ubiquinol oxidase subunit III. (205 aa)
Spro_1089KEGG: yen:YE3142 cytochrome o ubiquinol oxidase subunit I; TIGRFAM: Cytochrome o ubiquinol oxidase subunit I; PFAM: cytochrome c oxidase subunit I; Belongs to the heme-copper respiratory oxidase family. (663 aa)
Spro_1090TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; COX aromatic rich domain protein; KEGG: yen:YE3141 cytochrome o ubiquinol oxidase subunit II. (316 aa)
Spro_1525PFAM: NmrA family protein; KEGG: stp:Strop_2997 NmrA family protein. (279 aa)
acpP-2Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa)
Spro_2422TIGRFAM: high-affinity nickel-transporter; KEGG: plu:plu2170 putative high-affinity nickel-transport protein; Belongs to the NiCoT transporter (TC 2.A.52) family. (343 aa)
Spro_2423(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (765 aa)
Spro_2424TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: kpn:KPN_02090 formate dehydrogenase H, selenopolypeptide subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (718 aa)
Spro_2425PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: stm:STM2843 electron transport protein (FeS senter) from formate to hydrogen. (180 aa)
Spro_2426TIGRFAM: hydrogenase maturation protease; hydrogenase maturation protease HycI; hydrogenase maturation peptidase superfamily; PFAM: peptidase M52 hydrogen uptake protein; KEGG: sdy:SDY_2914 HycI. (156 aa)
Spro_2427PFAM: formate hydrogenlyase maturation HycH; KEGG: kpn:KPN_03055 processing of HycE (part of the FHL complex). (138 aa)
Spro_2428PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: ent:Ent638_3192 NADH ubiquinone oxidoreductase, 20 kDa subunit. (265 aa)
Spro_2429PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ecv:APECO1_3805 formate hydrogenlyase complex iron-sulfur protein. (181 aa)
Spro_2430PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: stm:STM2849 hydrogenase 3 large subunit. (567 aa)
Spro_2431PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: kpn:KPN_03059 hydrogenase 3, membrane subunit (part of FHL complex). (311 aa)
Spro_2432NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: spt:SPA2709 NADH dehydrogenase subunit N. (622 aa)
Spro_2433PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: stm:STM2852 hydrogenase-3 iron-sulfur subunit. (204 aa)
Spro_2434KEGG: stm:STM2853 transcriptional repressor. (155 aa)
hypAHydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (114 aa)
Spro_2436TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: stm:STM2855 hydrogenase-3 accessory protein, assembly of metallocenter. (264 aa)
Spro_2437TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: yen:YE2796 putative hydrogenase isoenzymes formation protein. (97 aa)
Spro_2438TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: yen:YE3602 hydrogenase isoenzymes formation protein; Belongs to the HypD family. (375 aa)
Spro_2439TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: sec:SC2791 putative hydrogenase expression/formation protein. (337 aa)
Spro_2440Transcriptional regulator, NifA subfamily, Fis Family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sbo:SBO_2789 formate hydrogen-lyase transcriptional activator for FdhF, hyc and hyp operons. (688 aa)
nuoNProton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (485 aa)
Spro_3297KEGG: ypi:YpsIP31758_1465 NADH-quinone oxidoreductase, M subunit; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I). (509 aa)
Spro_3298KEGG: eca:ECA3018 NADH-quinone oxidoreductase chain L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I). (615 aa)
nuoKNADH-ubiquinone oxidoreductase chain 4L; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
Spro_3300NADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (186 aa)
nuoINADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa)
nuoHNADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa)
Spro_3303NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (915 aa)
Spro_3304NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (450 aa)
Spro_3305TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: ypp:YPDSF_1962 NADH dehydrogenase I chain E. (183 aa)
nuoCNADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. (598 aa)
nuoBNADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (224 aa)
nuoANADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (146 aa)
Spro_3664PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ecv:APECO1_3969 putative 4Fe-4S cluster-containing protein. (86 aa)
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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