STRINGSTRING
Spro_0466 Spro_0466 Spro_0665 Spro_0665 Spro_0675 Spro_0675 Spro_1458 Spro_1458 Spro_1578 Spro_1578 Spro_1721 Spro_1721 cmoM cmoM mukF mukF mukE mukE mukB mukB Spro_1730 Spro_1730 zapC zapC matP matP Spro_1759 Spro_1759 hspQ hspQ Spro_1969 Spro_1969 Spro_2049 Spro_2049 Spro_2648 Spro_2648 Spro_2706 Spro_2706 Spro_2839 Spro_2839 Spro_2990 Spro_2990 Spro_2991 Spro_2991 Spro_3208 Spro_3208 Spro_3264 Spro_3264 Spro_3794 Spro_3794 zapA zapA Spro_4351 Spro_4351 Spro_4691 Spro_4691 zapB zapB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Spro_0466PFAM: protein of unknown function DUF1471; KEGG: yen:YE0412 hypothetical protein. (87 aa)
Spro_0665KEGG: yps:YPTB0585 membrane protein, transcribed divergently from SerB. (234 aa)
Spro_0675PFAM: Lytic transglycosylase catalytic; KEGG: yen:YE0589 putative soluble lytic murein transglycosylase. (642 aa)
Spro_1458PFAM: porin Gram-negative type; KEGG: yen:YE2856 outer membrane protein C2; Belongs to the Gram-negative porin family. (365 aa)
Spro_1578PFAM: AsmA family protein; KEGG: ypi:YpsIP31758_2451 AsmA protein. (611 aa)
Spro_1721PFAM: protein of unknown function DUF218; KEGG: yen:YE1552 putative inner membrane protein. (257 aa)
cmoMMethyltransferase type 11; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family. (261 aa)
mukFChromosome segregation and condensation protein MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. (440 aa)
mukEChromosome segregation and condensation protein MukE; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. (242 aa)
mukBChromosome segregation and condensation protein MukB domain protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. (1482 aa)
Spro_1730PFAM: porin Gram-negative type; KEGG: stm:STM1473 outer membrane protein N precursor; Belongs to the Gram-negative porin family. (369 aa)
zapCProtein of unknown function DUF1379; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. (182 aa)
matPProtein of unknown function DUF1047; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. (152 aa)
Spro_1759PFAM: UvrD/REP helicase; KEGG: yen:YE1586 putative helicase IV. (684 aa)
hspQHemimethylated DNA binding protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family. (105 aa)
Spro_1969PFAM: UspA domain protein; KEGG: ppr:PBPRA0125 putative universal stress protein A. (141 aa)
Spro_2049KEGG: kpn:KPN_00743 cell envelope integrity inner membrane protein TolA. (146 aa)
Spro_2648PFAM: protein of unknown function DUF1471; KEGG: kpn:KPN_00833 hypothetical protein. (86 aa)
Spro_2706PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: ypi:YpsIP31758_1966 DNA-binding protein H-NS; Belongs to the histone-like protein H-NS family. (135 aa)
Spro_2839PFAM: porin Gram-negative type; KEGG: yen:YE2463 outer membrane porin protein. (360 aa)
Spro_2990PFAM: Haemolysin expression modulating family protein; KEGG: ecp:ECP_1570 hypothetical protein YdgT. (71 aa)
Spro_2991PFAM: UspA domain protein; KEGG: yen:YE2583 putative universal stress protein. (139 aa)
Spro_3208PFAM: protein of unknown function DUF496; KEGG: ypi:YpsIP31758_2417 hypothetical protein; Belongs to the UPF0265 family. (105 aa)
Spro_3264PFAM: porin Gram-negative type; KEGG: yen:YE1401 outer membrane protein C, porin; Belongs to the Gram-negative porin family. (370 aa)
Spro_3794KEGG: yen:YE3288 hypothetical protein; Belongs to the UPF0325 family. (129 aa)
zapAProtein of unknown function DUF710; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (109 aa)
Spro_4351PFAM: protein of unknown function DUF1043; KEGG: yen:YE3743 hypothetical protein. (133 aa)
Spro_4691PFAM: UspA domain protein; KEGG: sdy:SDY_3567 universal stress protein; broad regulatory function?. (148 aa)
zapBProtein of unknown function DUF904; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. (79 aa)
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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