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| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | Spro_4869 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (703 aa) |
| | Spro_4882 | Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: ypi:YpsIP31758_0026 nitrogen regulation protein NR(II). (349 aa) |
| | srkA | Aminoglycoside phosphotransferase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (328 aa) |
| | Spro_1066 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: yen:YE1614 tetrathionate reductase complex: sensory transduction histidine kinase. (585 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (327 aa) |
| | adk | Nucleoside-triphosphate--adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | Spro_1142 | PFAM: glycerate kinase; KEGG: ypi:YpsIP31758_4052 glycerate kinase; Belongs to the glycerate kinase type-1 family. (382 aa) |
| | Spro_1144 | Inosine kinase; PFAM: PfkB domain protein; KEGG: yen:YE3069 inosine-guanosine kinase. (434 aa) |
| | Spro_1228 | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: stm:STM0685 Sugar Specific PTS family, n-acetylglucosamine-specific enzyme IIABC. (648 aa) |
| | Spro_1245 | PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Osmosensitive K channel His kinase sensor; UspA domain protein; KEGG: yen:YE2963 two-component regulatory protein sensor kinase KdpD. (897 aa) |
| | Spro_1285 | Hpt sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; SMART: extracellular solute-binding protein family 3; KEGG: pfo:Pfl_1864 Hpt sensor hybrid histidine kinase. (1070 aa) |
| | galK | Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (383 aa) |
| | Spro_1308 | PFAM: PEBP family protein; KEGG: kpn:KPN_00798 conserved protein, phosphatidylethanolamine-binding domain. (160 aa) |
| | lsrK | Carbohydrate kinase FGGY; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position. (521 aa) |
| | Spro_1386 | PFAM: protein of unknown function RIO1; KEGG: yen:YE1747 hypothetical protein. (282 aa) |
| | Spro_1421 | KEGG: ent:Ent638_1988 putative substrate-binding periplasmic transport protein. (422 aa) |
| | Spro_1491 | PFAM: type III effector Hrp-dependent outers; KEGG: eca:ECA4328 hypothetical protein. (420 aa) |
| | Spro_1499 | Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system. (474 aa) |
| | Spro_1507 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: pol:Bpro_0544 periplasmic sensor signal transduction histidine kinase. (488 aa) |
| | udk | TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: yen:YE2783 uridine kinase. (213 aa) |
| | Spro_1585 | Non-specific protein-tyrosine kinase; PFAM: lipopolysaccharide biosynthesis protein; KEGG: kpn:KPN_02510 tyrosine autokinase. (724 aa) |
| | cmk | Cytidylate kinase; KEGG: ypi:YpsIP31758_2581 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. (229 aa) |
| | rbsK | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (318 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (326 aa) |
| | Spro_1718 | PFAM: protein of unknown function DUF343; KEGG: ypi:YpsIP31758_2572 hypothetical protein; Belongs to the UPF0434 family. (60 aa) |
| | Spro_1834 | PFAM: UspA domain protein; KEGG: eca:ECA1769 hypothetical protein. (142 aa) |
| | Spro_1855 | PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: plu:plu2754 PTS system, cellobiose-specific IIB component. (101 aa) |
| | tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa) |
| | Spro_1914 | TIGRFAM: PTS system, maltose and glucose-specific subfamily, IIC subunit; PTS system, glucose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE1643 PTS system, glucose-specific IIBC component. (477 aa) |
| | thiK | Thiamine kinase; Catalyzes the phosphorylation of thiamine to thiamine phosphate. (289 aa) |
| | Spro_1959 | Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; KEGG: yen:YE2505 two-component system, sensor kinase. (533 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. (288 aa) |
| | Spro_1993 | KEGG: yen:YE2428 hypothetical protein. (269 aa) |
| | nagK | ROK family protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. (306 aa) |
| | Spro_2008 | TIGRFAM: PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: kpn:KPN_04015 phosphotransferase system PTS. (519 aa) |
| | Spro_2012 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PhoQ Sensor domain protein; KEGG: yen:YE1717 sensor protein kinase. (485 aa) |
| | Spro_2128 | Fructosamine kinase; PFAM: aminoglycoside phosphotransferase; fructosamine kinase; KEGG: yen:YE1896 hypothetical protein. (289 aa) |
| | Spro_2173 | Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (292 aa) |
| | Spro_2174 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa) |
| | Spro_2187 | KEGG: yen:YE2164 pyruvate kinase I; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (470 aa) |
| | anmK | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (373 aa) |
| | pdxY | Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. (286 aa) |
| | Spro_2242 | KEGG: yen:YE1996 hypothetical protein. (146 aa) |
| | araB | TIGRFAM: L-ribulokinase; PFAM: carbohydrate kinase FGGY; KEGG: ypp:YPDSF_0880 L-ribulokinase. (561 aa) |
| | Spro_2252 | KEGG: kpn:KPN_04198 putative serine protease. (198 aa) |
| | Spro_2253 | Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: kpn:KPN_04197 putative PTS family enzyme IIA component. (145 aa) |
| | Spro_2258 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (326 aa) |
| | Spro_2263 | TIGRFAM: PTS system, maltose and glucose-specific subfamily, IIC subunit; PTS system, maltose and glucose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE2011 PTS system, maltose and glucose-specific IIAbc component. (474 aa) |
| | Spro_2270 | KEGG: yen:YE2011 PTS system, maltose and glucose-specific IIAbc component. (74 aa) |
| | Spro_2294 | PFAM: PfkB domain protein; KEGG: ret:RHE_CH03378 probable sugar kinase protein; Belongs to the carbohydrate kinase PfkB family. (317 aa) |
| | Spro_2323 | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, beta-glucoside-specific IIABC subunit; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: eca:ECA0860 PTS system, IIabc component. (621 aa) |
| | Spro_2464 | PFAM: carbohydrate kinase FGGY; KEGG: ecv:APECO1_3757 putative sugar kinase YgcE. (481 aa) |
| | Spro_2560 | PFAM: protein of unknown function DUF344; KEGG: bur:Bcep18194_B1834 protein of unknown function DUF344. (304 aa) |
| | Spro_2566 | TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: kpn:KPN_02766 pyridoxine kinase; Belongs to the pyridoxine kinase family. (279 aa) |
| | Spro_2576 | PFAM: ROK family protein; KEGG: pin:Ping_1332 ROK family protein. (307 aa) |
| | Spro_2591 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ypi:YpsIP31758_1825 sensor protein RstB. (434 aa) |
| | Spro_2622 | TIGRFAM: shock protein C; PFAM: PspC domain protein; KEGG: yen:YE2119 phage shock protein C. (119 aa) |
| | Spro_2692 | PFAM: carbohydrate kinase FGGY; KEGG: pae:PA1487 probable carbohydrate kinase; Belongs to the FGGY kinase family. (480 aa) |
| | tdk | PFAM: thymidine kinase; KEGG: ypi:YpsIP31758_1964 thymidine kinase. (194 aa) |
| | rssB | Response regulator receiver protein; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. (337 aa) |
| | selD | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (347 aa) |
| | Spro_2731 | PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: yen:YE2272 hypothetical protein. (644 aa) |
| | Spro_2770 | KEGG: eca:ECA2481 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (480 aa) |
| | Spro_2799 | PFAM: ABC-1 domain protein; KEGG: sfr:Sfri_1807 ABC-1 domain protein. (546 aa) |
| | Spro_2813 | KEGG: yps:YPTB1634 PTS system, mannose-specific IIAB component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PTS system, mannose/fructose/sorbose family, IIA subunit; PFAM: PTS system fructose subfamily IIA component; PTS system sorbose subfamily IIB component. (323 aa) |
| | Spro_2893 | Non-specific protein-tyrosine kinase; PFAM: lipopolysaccharide biosynthesis protein; KEGG: eca:ECA1419 tyrosine-protein kinase. (727 aa) |
| | Spro_2899 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: eca:ECA2029 nitrate/nitrite sensor kinase. (594 aa) |
| | Spro_2903 | PFAM: PEBP family protein; KEGG: reu:Reut_B3733 YbhB and YbcL. (188 aa) |
| | Spro_2985 | CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheY binding; KEGG: yen:YE2577 chemotaxis protein CheA. (655 aa) |
| | Spro_3014 | SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: azo:azo3888 putative serine/threonine kinase. (480 aa) |
| | Spro_3111 | KEGG: eca:ECA1481 hypothetical protein. (205 aa) |
| | Spro_3187 | Carbamate kinase; KEGG: hip:CGSHiEE_09190 carbamate kinase; TIGRFAM: carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the carbamate kinase family. (308 aa) |
| | Spro_3229 | 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: yen:YE1448 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (313 aa) |
| | rcsD | Multi-sensor signal transduction histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (900 aa) |
| | rcsC | Integral membrane sensor hybrid histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (957 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa) |
| | Spro_1042 | PAS/PAC sensor signal transduction histidine kinase; KEGG: yen:YE3181 phosphate regulon sensor protein PhoR; TIGRFAM: PAS sensor protein; Phosphate regulon sensor kinase PhoR; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (438 aa) |
| | Spro_1036 | PFAM: ROK family protein; KEGG: kpn:KPN_00337 possible NAGC-like transcriptional regulator. (302 aa) |
| | Spro_1034 | PFAM: PfkB domain protein; KEGG: yps:YPTB3802 PfkB family carbohydrate kinase. (337 aa) |
| | aroL | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. (174 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa) |
| | mtnK | 5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (399 aa) |
| | Spro_0834 | TIGRFAM: PTS system, lactose/cellobiose family IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: ypm:YP_2480 PTS system, cellobiose-specific IIB component. (126 aa) |
| | cysC | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (209 aa) |
| | Spro_0792 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (743 aa) |
| | Spro_0790 | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: ypm:YP_0304 two-component regulatory protein. (906 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (204 aa) |
| | Spro_0697 | KEGG: ypi:YpsIP31758_3461 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: cytidylyltransferase; FAD synthetase; Riboflavin kinase; Belongs to the ribF family. (312 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa) |
| | Spro_0683 | Aspartate kinase; KEGG: yps:YPTB0602 bifunctional ThrA; aspartokinase I and homoserine dehydrogenase I (C-terminal); TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. (819 aa) |
| | Spro_0668 | Transcriptional regulator, XRE family; TIGRFAM: cytidyltransferase-related domain; nicotinamide-nucleotide adenylyltransferase; PFAM: helix-turn-helix domain protein; KEGG: yps:YPTB0588 transcriptional regulator NadR. (419 aa) |
| | Spro_0576 | PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE1256 PTS transport protein. (480 aa) |
| | Spro_0570 | PFAM: ATP-binding region ATPase domain protein; KEGG: azo:azo0358 putative two-component sensor kinase. (720 aa) |
| | Spro_0568 | KEGG: kpn:KPN_04693 hypothetical protein. (116 aa) |
| | Spro_0529 | TIGRFAM: PTS system, trehalose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE3774 PTS system, trehalose-specific IIBC component. (471 aa) |
| | phnN | Phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (189 aa) |
| | Spro_0477 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE0422 two-component system sensor protein. (353 aa) |
| | coaA | KEGG: ypi:YpsIP31758_3870 pantothenate kinase; TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase. (316 aa) |
| | ubiB | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (543 aa) |
| | wzzE | Lipopolysaccharide biosynthesis protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. (350 aa) |
| | Spro_0133 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; MASE1 domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: ypi:YpsIP31758_4079 sensor histidine kinase UhpB. (513 aa) |
| | xylB | TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: yen:YE4123 xylulose kinase. (483 aa) |
| | Spro_0059 | PFAM: PfkB domain protein; KEGG: kpn:KPN_03913 putative kinase. (319 aa) |
| | Spro_0042 | 2-dehydro-3-deoxygalactonokinase; PFAM: 2-keto-3-deoxy-galactonokinase; KEGG: eca:ECA4418 2-dehydro-3-deoxygalactonokinase. (297 aa) |
| | Spro_3339 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: plu:plu3178 two-component sensor kinase. (472 aa) |
| | Spro_3404 | Signal transduction histidine kinase, LytS; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: yen:YE1228 two-component system histidine kinase. (563 aa) |
| | glk | Glucokinase; KEGG: ecv:APECO1_4149 glucokinase; TIGRFAM: glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. (320 aa) |
| | Spro_3449 | Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa) |
| | Spro_3451 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE1202 putative two-component system sensor kinase. (442 aa) |
| | Spro_3489 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: eca:ECA1900 nitrate/nitrite sensor protein. (560 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (687 aa) |
| | Spro_3543 | Diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: GGDEF domain containing protein; KEGG: kpn:KPN_02828 putative cytochrome c-type biogenesis protein. (750 aa) |
| | Spro_3550 | Kinase; KEGG: asa:ASA_4263 predicted kinase. (169 aa) |
| | Spro_3556 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE1105 two-component system, sensor kinase. (460 aa) |
| | Spro_3562 | Diacylglycerol kinase catalytic region; Probably phosphorylates lipids; the in vivo substrate is unknown. (305 aa) |
| | Spro_3577 | KEGG: eca:ECA3196 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. (266 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (264 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa) |
| | Spro_3653 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ypi:YpsIP31758_1150 putative sensor-like histidine kinase YfhK. (478 aa) |
| | Spro_3660 | PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: ent:Ent638_3046 phosphotransferase system, EIIC. (455 aa) |
| | nadK | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (292 aa) |
| | Spro_3731 | Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; SMART: PAS domain containing protein; KEGG: eca:ECA2577 two-component sensor kinase. (532 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa) |
| | Spro_3844 | PFAM: PTS system fructose subfamily IIA component; KEGG: plu:plu0838 unnamed protein product; similar to putative PTS system IIA component YadI of Escherichia coli. (144 aa) |
| | Spro_3847 | KEGG: plu:plu0835 PTS system, N-acetylgalactosamine-specific IIB component 2 (EIIB-AGA') (N-acetylgalactosamine-permease IIB component 2) (phosphotransferase enzyme II, B component 2); TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PFAM: PTS system sorbose subfamily IIB component. (158 aa) |
| | Spro_3848 | Tagatose-6-phosphate kinase; PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; KEGG: plu:plu0833 putative tagatose 6-phosphate kinase AgaZ. (427 aa) |
| | Spro_3895 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE3383 putative histidine kinase sensor. (472 aa) |
| | Spro_3911 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: eba:ebA6233 sensor histidine kinase. (468 aa) |
| | Spro_3936 | PFAM: carbohydrate kinase FGGY; KEGG: eci:UTI89_C4124 cryptic L-xylulose kinase; Belongs to the FGGY kinase family. (493 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: yen:YE3414 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (386 aa) |
| | Spro_3988 | KEGG: ypi:YpsIP31758_3341 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. (166 aa) |
| | Spro_3989 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: eca:ECA0007 two-component system sensor kinase. (452 aa) |
| | Spro_4054 | Histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sec:SC039 hypothetical protein. (547 aa) |
| | Spro_4203 | PFAM: PfkB domain protein; KEGG: yen:YE0554 fructokinase; Belongs to the carbohydrate kinase PfkB family. (309 aa) |
| | Spro_4205 | TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE0552 PTS system, sucrose-specific IIBC component. (456 aa) |
| | Spro_4224 | PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: eca:ECA4435 pts system, IIb component. (103 aa) |
| | Spro_4232 | PFAM: ROK family protein; KEGG: sdy:SDY_2740 putative NAGC-like transcriptional regulator. (400 aa) |
| | Spro_4270 | Dihydroxyacetone kinase, phosphotransfer subunit; KEGG: yen:YE0542 multifunctional PTS-system sugar transferase; TIGRFAM: phosphocarrier, HPr family; dihydroxyacetone kinase, phosphotransfer subunit; PFAM: phosphocarrier HPr protein; PTS system fructose subfamily IIA component; PEP-utilising protein mobile region; PEP-utilising protein domain protein; Belongs to the PEP-utilizing enzyme family. (477 aa) |
| | Spro_4271 | TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: Dak phosphatase; KEGG: yen:YE0541 hypothetical protein. (210 aa) |
| | Spro_4272 | Dihydroxyacetone kinase, DhaK subunit; KEGG: yen:YE0540 putative dihydroxyacetone kinase; TIGRFAM: dihydroxyacetone kinase, DhaK subunit; PFAM: Dak kinase. (356 aa) |
| | Spro_4280 | PFAM: PTS system sorbose subfamily IIB component; KEGG: aha:AHA_2341 PTS system mannose-specific EIIAB component (EIIAB-man). (164 aa) |
| | Spro_4281 | PFAM: PTS system fructose subfamily IIA component; KEGG: aha:AHA_2342 PTS system, mannose/fructose/sorbose family, IIA component. (142 aa) |
| | hldE | rfaE bifunctional protein; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. (476 aa) |
| | Spro_4342 | Multi-sensor hybrid histidine kinase; KEGG: ypi:YpsIP31758_0469 putative aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (779 aa) |
| | rnk | GreA/GreB family elongation factor; May act as an anti-Gre factor; Belongs to the Rnk family. (136 aa) |
| | Spro_4461 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (122 aa) |
| | Spro_4479 | Aspartate kinase; KEGG: ypi:YpsIP31758_0301 asparate kinase, monofunctional class; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (455 aa) |
| | Spro_4497 | KEGG: stm:STM3542 gluconate kinase 2; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase. (179 aa) |
| | aceK | (Isocitrate dehydrogenase (NADP(+))) kinase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (584 aa) |
| | slyX | PFAM: SlyX family protein; KEGG: ype:YPO0194 SlyX protein; Belongs to the SlyX family. (75 aa) |
| | Spro_4578 | PFAM: phosphoribulokinase/uridine kinase; KEGG: yen:YE3953 phosphoribulokinase 1. (289 aa) |
| | Spro_4588 | Signal transduction histidine kinase, LytS; PFAM: ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; SMART: GAF domain protein; KEGG: ecv:APECO1_4423 putative sensory kinase in two-component system with YehT. (561 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | Spro_4620 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE4005 osmolarity sensor protein. (459 aa) |
| | Spro_4650 | KEGG: sgl:SG2151 putative gluconokinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase. (175 aa) |
| | Spro_4660 | PFAM: PfkB domain protein; KEGG: yen:YE4028 putative carbohydrate kinase. (642 aa) |
| | Spro_4697 | TIGRFAM: FGGY-family pentulose kinase; PFAM: carbohydrate kinase FGGY; KEGG: ypi:YpsIP31758_0368 pentulose kinase, FGGY family. (545 aa) |
| | Spro_4735 | Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sec:SC039 hypothetical protein. (594 aa) |
| | Spro_4750 | PFAM: PfkB domain protein; KEGG: ypi:YpsIP31758_4062 2-dehydro-3-deoxygluconokinase. (310 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. (257 aa) |
| | Spro_4785 | Aspartate kinase; KEGG: yen:YE0112 bifunctional aspartokinase/homoserine dehydrogenase II; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. (811 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (502 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa) |
| | Spro_4811 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE0085 two component sensor kinase. (457 aa) |
