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| | gyrB | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (804 aa) |
| | xylA | KEGG: ypi:YpsIP31758_4102 xylose isomerase; TIGRFAM: xylose isomerase; PFAM: Xylose isomerase domain protein TIM barrel; Belongs to the xylose isomerase family. (439 aa) |
| | Spro_0155 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: kpn:KPN_04275 peptidyl-prolyl cis-trans isomerase C (rotamase C). (111 aa) |
| | wecB | UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. (376 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (274 aa) |
| | Spro_0187 | KEGG: kpn:KPN_02730 hypothetical protein. (159 aa) |
| | fadB | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (729 aa) |
| | Spro_0310 | DNA topoisomerase III; KEGG: plu:plu1037 unnamed protein product; similar to DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase type IA central domain protein; DNA topoisomerase type IA zn finger domain protein; SMART: DNA topoisomerase I ATP-binding; DNA topoisomerase I DNA-binding; Toprim sub domain protein. (679 aa) |
| | groL | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (548 aa) |
| | nnrD | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. (462 aa) |
| | Spro_0452 | PFAM: peptidylprolyl isomerase FKBP-type; KEGG: eca:ECA3607 FkbP-type peptidyl-prolyl cis-trans isomerase. (206 aa) |
| | glmM | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (445 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (314 aa) |
| | Spro_0625 | KEGG: plu:plu0990 hypothetical protein; TIGRFAM: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, HpaG1 subunit; PFAM: fumarylacetoacetate (FAA) hydrolase. (210 aa) |
| | Spro_0629 | PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: plu:plu0986 5-carboxymethyl-2-hydroxy-muconic acid isomerase. (128 aa) |
| | Spro_0639 | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: ypi:YpsIP31758_2411 fumarylacetoacetate hydrolase family protein. (281 aa) |
| | Spro_0643 | KEGG: rfr:Rfer_3138 hypothetical protein. (119 aa) |
| | deoB | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (407 aa) |
| | gpmB | PFAM: Phosphoglycerate mutase; KEGG: plu:plu0559 phosphoglyceromutase 2; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa) |
| | Spro_0700 | PFAM: peptidylprolyl isomerase FKBP-type; KEGG: ypp:YPDSF_3155 FKBP-type peptidyl-prolyl cis-trans isomerase. (156 aa) |
| | apaG | PFAM: ApaG domain protein; KEGG: yen:YE0629 ApaG protein homologue. (125 aa) |
| | surA | SurA domain; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (432 aa) |
| | Spro_0729 | PFAM: pseudouridine synthase; KEGG: eca:ECA3854 ribosomal large subunit pseudouridine synthase A. (216 aa) |
| | hemL | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: yen:YE0734 glutamate-1-semialdehyde 2,1-aminomutase. (429 aa) |
| | truD | tRNA pseudouridine synthase D TruD; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (348 aa) |
| | Spro_0880 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: yen:YE0851 T-protein. (373 aa) |
| | Spro_0881 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: yen:YE0852 P-protein. (385 aa) |
| | Spro_0884 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (325 aa) |
| | Spro_0915 | PFAM: Asp/Glu racemase; KEGG: kpn:KPN_01788 putative hydantoin racemase. (247 aa) |
| | mtnC | 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (229 aa) |
| | mtnA | eIF-2B alpha/beta/delta-related uncharacterized protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (342 aa) |
| | gmhA | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (193 aa) |
| | Spro_1025 | PFAM: AroM family protein; KEGG: ssn:SSON_0366 protein of aro operon, regulated by AroR. (225 aa) |
| | Spro_1032 | PFAM: protein of unknown function DUF1498; KEGG: yps:YPTB3804 hypothetical protein. (228 aa) |
| | queA | S-adenosylmethionine--tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (356 aa) |
| | tig | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (434 aa) |
| | Spro_1099 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: yen:YE3130 peptidyl-prolyl cis-trans isomerase D. (627 aa) |
| | Spro_1161 | TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KR domain protein; KEGG: plu:plu4831 UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase). (338 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (174 aa) |
| | Spro_1165 | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (164 aa) |
| | nagB | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (266 aa) |
| | Spro_1234 | TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: plu:plu4831 UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase). (350 aa) |
| | Spro_1241 | TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: yen:YE2967 phosphoglucomutase. (547 aa) |
| | gpmA | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa) |
| | Spro_1290 | Galactose mutarotase; Converts alpha-aldose to the beta-anomer. (347 aa) |
| | lsrG | Antibiotic biosynthesis monooxygenase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family. (97 aa) |
| | Spro_1460 | KEGG: cvi:CV_3287 probable tautomerase. (144 aa) |
| | Spro_1489 | PFAM: Xylose isomerase domain protein TIM barrel; KEGG: eca:ECA4330 putative isomerase; Belongs to the hyi family. (258 aa) |
| | Spro_1600 | Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: ent:Ent638_2662 phosphomannomutase. (455 aa) |
| | Spro_1601 | TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KR domain protein; KEGG: plu:plu4831 UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase). (337 aa) |
| | hisA | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; histidine biosynthesis protein; KEGG: ypi:YpsIP31758_2433 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (245 aa) |
| | Spro_1660 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: yen:YE1503 hypothetical protein. (336 aa) |
| | Spro_1696 | KEGG: plu:plu2181 hypothetical protein; Belongs to the 4-oxalocrotonate tautomerase family. (71 aa) |
| | fabA | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (172 aa) |
| | Spro_1827 | PFAM: Antibiotic biosynthesis monooxygenase; KEGG: yen:YE3018 hypothetical protein. (99 aa) |
| | Spro_1840 | PFAM: proline racemase; KEGG: pap:PSPA7_4122 hypothetical protein. (315 aa) |
| | Spro_1897 | PFAM: Antibiotic biosynthesis monooxygenase; KEGG: yen:YE1626 hypothetical protein. (95 aa) |
| | Spro_1899 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (320 aa) |
| | Spro_2024 | PFAM: pseudouridine synthase; KEGG: yen:YE1724 putative pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. (178 aa) |
| | Spro_2051 | TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: 4-oxalocrotonate tautomerase; KEGG: pen:PSEEN1931 4-oxalocrotonate tautomerase. (72 aa) |
| | Spro_2074 | Chorismate mutase, putative; Catalyzes the Claisen rearrangement of chorismate to prephenate. (176 aa) |
| | Spro_2090 | PFAM: protein of unknown function DUF453; KEGG: kpn:KPN_04047 hypothetical protein. (363 aa) |
| | idi | Isopentenyl-diphosphate delta-isomerase, type 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (179 aa) |
| | araA | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (501 aa) |
| | Spro_2277 | TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; KEGG: yen:YE2015 mannose-6-phosphate isomerase. (392 aa) |
| | maiA | Asp/Glu racemase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate. (250 aa) |
| | Spro_2372 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KR domain protein; KEGG: ppu:PP_2986 oxidoreductase, putative. (339 aa) |
| | Spro_2394 | PFAM: Xylose isomerase domain protein TIM barrel; KEGG: psp:PSPPH_2335 AP endonuclease, family 2 superfamily; Belongs to the hyi family. (259 aa) |
| | Spro_2544 | PFAM: AP endonuclease 2 domain protein; Xylose isomerase domain protein TIM barrel; KEGG: pfl:PFL_3507 AP endonuclease family 2 protein. (351 aa) |
| | Spro_2578 | TIGRFAM: Sugar isomerase AgaS; PFAM: sugar isomerase (SIS); KEGG: plu:plu0834 putative tagatose-6-phosphate ketose/aldose isomerase. (388 aa) |
| | Spro_2615 | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: yps:YPTB2260 putative mandelate racemase / muconate lactonizing protein. (326 aa) |
| | Spro_2644 | KEGG: eca:ECA1960 L-ribulose-5-phosphate 4-epimerase; TIGRFAM: L-ribulose-5-phosphate 4-epimerase; PFAM: class II aldolase/adducin family protein. (231 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (865 aa) |
| | Spro_2662 | Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: ypi:YpsIP31758_1928 ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. (299 aa) |
| | trpF | Indole-3-glycerol-phosphate synthase/phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Indole-3-glycerol phosphate synthase; KEGG: yen:YE2212 tryptophan biosynthesis protein TrpCF. (453 aa) |
| | topB | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] (641 aa) |
| | Spro_2729 | PFAM: Aldose 1-epimerase; KEGG: yps:YPTB2082 hypothetical protein; Belongs to the glucose-6-phosphate 1-epimerase family. (291 aa) |
| | Spro_2745 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (357 aa) |
| | Spro_2868 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ypi:YpsIP31758_2107 NAD-dependent epimerase/dehydratase family protein. (338 aa) |
| | Spro_2896 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: tde:TDE1439 epimerase/dehydratase, putative. (318 aa) |
| | Spro_3078 | TIGRFAM: phenylacetate degradation probable enoyl-CoA hydratase paaB; PFAM: Enoyl-CoA hydratase/isomerase; KEGG: kpn:KPN_01475 enoyl-CoA hydratase. (263 aa) |
| | Spro_3195 | PFAM: Xylose isomerase domain protein TIM barrel; KEGG: bsu:BG11855 unknown. (313 aa) |
| | Spro_3252 | Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: yen:YE1424 ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family. (237 aa) |
| | gyrA | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (882 aa) |
| | menF | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. (432 aa) |
| | Spro_3313 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yen:YE1337 putative haloacid dehalogenase-like hydrolase. (218 aa) |
| | Spro_3321 | PFAM: dihydroneopterin aldolase; KEGG: sdy:SDY_2500 D-erythro-7,8-dihydroneopterin tri P epimerase. (123 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (273 aa) |
| | fadJ | Fatty acid oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (721 aa) |
| | Spro_3409 | TIGRFAM: aspartate racemase; PFAM: Asp/Glu racemase; KEGG: yen:YE1289 putative aspartate/glutamate racemase. (230 aa) |
| | Spro_3421 | TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: kpn:KPN_00611 isochorismate synthase. (402 aa) |
| | Spro_3575 | KpsF/GutQ family protein; KEGG: yen:YE1092 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). (323 aa) |
| | Spro_3581 | PFAM: Xylose isomerase domain protein TIM barrel; KEGG: ecs:ECs4795 hypothetical protein. (325 aa) |
| | Spro_3586 | Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: ypi:YpsIP31758_2990 RNA pseudouridine synthase family protein; Belongs to the pseudouridine synthase RsuA family. (266 aa) |
| | Spro_3796 | PFAM: pseudouridine synthase; KEGG: ypi:YpsIP31758_1007 tRNA pseudouridine synthase. (256 aa) |
| | Spro_3857 | PFAM: 4-oxalocrotonate tautomerase; KEGG: kpn:KPN_02461 putative 4-oxalocrotonate tautomerase. (129 aa) |
| | Spro_3891 | Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (238 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (239 aa) |
| | Spro_3938 | KEGG: sec:SC3602 putative 3-hexulose-6-phosphate isomerase; TIGRFAM: putative hexulose-6-phosphate isomerase; PFAM: Xylose isomerase domain protein TIM barrel. (286 aa) |
| | Spro_3939 | KEGG: yps:YPTB2152 L-ribulose-5-phosphate 4-epimerase; TIGRFAM: L-ribulose-5-phosphate 4-epimerase; PFAM: class II aldolase/adducin family protein. (233 aa) |
| | Spro_3940 | PFAM: pseudouridine synthase; KEGG: yen:YE2636 putative ribosomal large subunit pseudouridine synthase. (232 aa) |
| | Spro_3971 | Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: ent:Ent638_0226 pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. (286 aa) |
| | Spro_4005 | PFAM: alanine racemase domain protein; KEGG: yen:YE3103 hypothetical protein. (388 aa) |
| | Spro_4006 | Phosphopentomutase; PFAM: metalloenzyme domain protein; Phosphopentomutase domain protein; KEGG: yen:YE3104 metalloenzyme superfamily protein. (411 aa) |
| | Spro_4107 | DNA topoisomerase III; KEGG: plu:plu1037 unnamed protein product; similar to DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase type IA central domain protein; DNA topoisomerase type IA zn finger domain protein; SMART: DNA topoisomerase I ATP-binding; DNA topoisomerase I DNA-binding; Toprim sub domain protein. (679 aa) |
| | Spro_4152 | PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: kpn:KPN_00128 hypothetical protein. (538 aa) |
| | Spro_4225 | PFAM: Aldose 1-epimerase; KEGG: ecj:JW2528 conserved hypothetical protein. (295 aa) |
| | parC | DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (757 aa) |
| | parE | DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (631 aa) |
| | Spro_4276 | PFAM: glucose-6-phosphate isomerase; Cupin 2 conserved barrel domain protein; KEGG: aha:AHA_2345 glucose-6-phosphate isomerase. (187 aa) |
| | Spro_4277 | KEGG: pdi:BDI_3293 putative thermophilic glucose-6-phosphate isomerase-like protein. (260 aa) |
| | Spro_4282 | KEGG: aha:AHA_2343 hypothetical protein. (598 aa) |
| | Spro_4295 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (119 aa) |
| | uxaC | PFAM: Glucuronate isomerase; KEGG: yen:YE3708 uronate isomerase. (470 aa) |
| | Spro_4362 | KpsF/GutQ family protein; KEGG: yen:YE3754 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). (328 aa) |
| | Spro_4448 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (359 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: yen:YE3870 glucose-6-phosphate isomerase; Belongs to the GPI family. (548 aa) |
| | Spro_4508 | PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: kpn:KPN_03684 putative DNA topoisomerase. (181 aa) |
| | Spro_4556 | PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: yen:YE3935 peptidyl-prolyl cis-trans isomerase. (277 aa) |
| | Spro_4558 | PFAM: peptidylprolyl isomerase FKBP-type; KEGG: ent:Ent638_3766 peptidylprolyl isomerase, FKBP-type. (200 aa) |
| | Spro_4568 | PFAM: AP endonuclease 2 domain protein; Xylose isomerase domain protein TIM barrel; KEGG: kpn:KPN_00539 putative xylose isomerase-like TIM barrel. (354 aa) |
| | Spro_4589 | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (189 aa) |
| | Spro_4601 | PFAM: ribulose-phosphate 3-epimerase; KEGG: stm:STM3483 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa) |
| | Spro_4625 | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: pna:Pnap_2474 5-carboxymethyl-2-hydroxymuconate delta-isomerase. (287 aa) |
| | Spro_4662 | PFAM: Myo-inositol catabolism IolB domain protein; KEGG: yen:YE4030 hypothetical protein. (273 aa) |
| | Spro_4669 | PFAM: peptidylprolyl isomerase FKBP-type; KEGG: ent:Ent638_0982 peptidylprolyl isomerase, FKBP-type. (382 aa) |
| | Spro_4698 | PFAM: sugar isomerase (SIS); KEGG: ypi:YpsIP31758_0369 SIS domain protein. (199 aa) |
| | Spro_4733 | KEGG: bxe:Bxe_B2768 hypothetical protein. (215 aa) |
| | Spro_4749 | TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: 4-oxalocrotonate tautomerase; KEGG: yps:YPTB3829 possible tautomerase enzyme. (67 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (287 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa) |
| | gpmI | Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (514 aa) |
| | hldD | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (309 aa) |
| | rbsD | RbsD or FucU transport; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (139 aa) |
