STRINGSTRING
Spro_3732 Spro_3732 Spro_3895 Spro_3895 Spro_3896 Spro_3896 Spro_3910 Spro_3910 Spro_3989 Spro_3989 Spro_3990 Spro_3990 Spro_4342 Spro_4342 Spro_4620 Spro_4620 Spro_4621 Spro_4621 Spro_4810 Spro_4810 ntrC ntrC Spro_4811 Spro_4811 Spro_0477 Spro_0477 Spro_0478 Spro_0478 Spro_0681 Spro_0681 Spro_0790 Spro_0790 Spro_1035 Spro_1035 Spro_1041 Spro_1041 Spro_1244 Spro_1244 Spro_1498 Spro_1498 Spro_1499 Spro_1499 Spro_1507 Spro_1507 Spro_1508 Spro_1508 Spro_1958 Spro_1958 Spro_2012 Spro_2012 Spro_2013 Spro_2013 Spro_2590 Spro_2590 Spro_2591 Spro_2591 Spro_2899 Spro_2899 Spro_3172 Spro_3172 rcsD rcsD rcsB rcsB rcsC rcsC Spro_3339 Spro_3339 Spro_3340 Spro_3340 Spro_3451 Spro_3451 Spro_3452 Spro_3452 Spro_3489 Spro_3489 Spro_3556 Spro_3556 Spro_3557 Spro_3557
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Spro_3732Response regulator receiver and unknown domain protein; PFAM: response regulator receiver; KEGG: eca:ECA2578 two-component response regulator. (229 aa)
Spro_3895Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE3383 putative histidine kinase sensor. (472 aa)
Spro_3896Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yps:YPTB3171 putative response regulator CreB family. (231 aa)
Spro_3910Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bch:Bcen2424_4924 two component transcriptional regulator, winged helix family. (219 aa)
Spro_3989Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: eca:ECA0007 two-component system sensor kinase. (452 aa)
Spro_3990Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: eca:ECA0008 two-component system response regulator. (220 aa)
Spro_4342Multi-sensor hybrid histidine kinase; KEGG: ypi:YpsIP31758_0469 putative aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (779 aa)
Spro_4620Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE4005 osmolarity sensor protein. (459 aa)
Spro_4621Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yen:YE4004 transcriptional regulatory protein. (239 aa)
Spro_4810Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ecp:ECP_4122 transcriptional regulatory protein CpxR. (232 aa)
ntrCNitrogen metabolism transcriptional regulator, NtrC, Fis Family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (470 aa)
Spro_4811Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE0085 two component sensor kinase. (457 aa)
Spro_0477Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE0422 two-component system sensor protein. (353 aa)
Spro_0478Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ypi:YpsIP31758_3607 transcriptional regulatory protein BasR/PmrA. (220 aa)
Spro_0681Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yen:YE0595 aerobic respiration control protein. (238 aa)
Spro_0790Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: ypm:YP_0304 two-component regulatory protein. (906 aa)
Spro_1035Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ent:Ent638_0283 two component transcriptional regulator, winged helix family. (246 aa)
Spro_1041Two component transcriptional regulator, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ypi:YpsIP31758_3136 phosphate regulon transcriptional regulatory protein PhoB. (229 aa)
Spro_1244Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: eca:ECA1338 two-component response regulator of kdp operon. (229 aa)
Spro_1498TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pae:PA4885 two-component response regulator. (223 aa)
Spro_1499Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system. (474 aa)
Spro_1507Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: pol:Bpro_0544 periplasmic sensor signal transduction histidine kinase. (488 aa)
Spro_1508Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bur:Bcep18194_C6809 two component transcriptional regulator, winged helix family. (237 aa)
Spro_1958Response regulator receiver and unknown domain protein; PFAM: response regulator receiver; KEGG: eca:ECA4398 two-component response regulator. (237 aa)
Spro_2012Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PhoQ Sensor domain protein; KEGG: yen:YE1717 sensor protein kinase. (485 aa)
Spro_2013Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ypi:YpsIP31758_1608 transcriptional regulatory protein PhoP. (223 aa)
Spro_2590Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yen:YE2083 two-component regulatory system, response regulator protein. (253 aa)
Spro_2591Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ypi:YpsIP31758_1825 sensor protein RstB. (434 aa)
Spro_2899Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: eca:ECA2029 nitrate/nitrite sensor kinase. (594 aa)
Spro_3172PFAM: response regulator receiver; KEGG: yen:YE2655 response regulator protein. (228 aa)
rcsDMulti-sensor signal transduction histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (900 aa)
rcsBTwo component transcriptional regulator, LuxR family; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. (216 aa)
rcsCIntegral membrane sensor hybrid histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (957 aa)
Spro_3339Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: plu:plu3178 two-component sensor kinase. (472 aa)
Spro_3340Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: plu:plu3179 two-component response regulator. (224 aa)
Spro_3451Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE1202 putative two-component system sensor kinase. (442 aa)
Spro_3452Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yen:YE1201 putative two-component system response regulator. (226 aa)
Spro_3489Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: eca:ECA1900 nitrate/nitrite sensor protein. (560 aa)
Spro_3556Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE1105 two-component system, sensor kinase. (460 aa)
Spro_3557Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yen:YE1104 two-component system response regulator. (239 aa)
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.