STRINGSTRING
acs acs fbp fbp Spro_0575 Spro_0575 Spro_0576 Spro_0576 gpmB gpmB eno eno Spro_0836 Spro_0836 Spro_1033 Spro_1033 Spro_1241 Spro_1241 gpmA gpmA Spro_1290 Spro_1290 Spro_1557 Spro_1557 Spro_1857 Spro_1857 Spro_1914 Spro_1914 Spro_2007 Spro_2007 pckA pckA Spro_2174 Spro_2174 Spro_2187 Spro_2187 Spro_2255 Spro_2255 Spro_2258 Spro_2258 Spro_2263 Spro_2263 Spro_2324 Spro_2324 Spro_2403 Spro_2403 Spro_2410 Spro_2410 Spro_2500 Spro_2500 Spro_2604 Spro_2604 Spro_2704 Spro_2704 Spro_2728 Spro_2728 Spro_2729 Spro_2729 Spro_2770 Spro_2770 Spro_3119 Spro_3119 Spro_3164 Spro_3164 glk glk Spro_3450 Spro_3450 Spro_3568 Spro_3568 Spro_3658 Spro_3658 Spro_3867 Spro_3867 Spro_3944 Spro_3944 pgk pgk Spro_4009 Spro_4009 Spro_4010 Spro_4010 Spro_4011 Spro_4011 Spro_4221 Spro_4221 Spro_4225 Spro_4225 Spro_4276 Spro_4276 Spro_4277 Spro_4277 Spro_4441 Spro_4441 pgi pgi Spro_4591 Spro_4591 pckA-2 pckA-2 Spro_4777 Spro_4777 Spro_4799 Spro_4799 tpiA tpiA pfkA pfkA gpmI gpmI Spro_4879 Spro_4879
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
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acsacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (652 aa)
fbpPFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: ypi:YpsIP31758_3621 fructose-1,6-bisphosphatase. (334 aa)
Spro_0575PFAM: glycoside hydrolase family 1; KEGG: sdy:SDY_2912 6-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family. (476 aa)
Spro_0576PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE1256 PTS transport protein. (480 aa)
gpmBPFAM: Phosphoglycerate mutase; KEGG: plu:plu0559 phosphoglyceromutase 2; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (431 aa)
Spro_0836Beta-glucosidase; PFAM: glycoside hydrolase family 1; KEGG: yen:YE0969 putative glycosyl hydrolase; Belongs to the glycosyl hydrolase 1 family. (461 aa)
Spro_1033Ketose-bisphosphate aldolase; KEGG: ypi:YpsIP31758_4026 putative fructose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II. (286 aa)
Spro_1241TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: yen:YE2967 phosphoglucomutase. (547 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa)
Spro_1290Galactose mutarotase; Converts alpha-aldose to the beta-anomer. (347 aa)
Spro_1557TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: yen:YE2821 probable alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa)
Spro_1857PFAM: glycoside hydrolase family 4; KEGG: ypi:YpsIP31758_3951 6-phospho-beta-glucosidase. (433 aa)
Spro_1914TIGRFAM: PTS system, maltose and glucose-specific subfamily, IIC subunit; PTS system, glucose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE1643 PTS system, glucose-specific IIBC component. (477 aa)
Spro_2007PFAM: glycoside hydrolase family 4; KEGG: kpn:KPN_04016 putative glycoside hydrolase, family 4. (461 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (539 aa)
Spro_2174Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
Spro_2187KEGG: yen:YE2164 pyruvate kinase I; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (470 aa)
Spro_2255KEGG: kpn:KPN_04196 putative ketose-bisphosphate aldolase, class-II; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II. (280 aa)
Spro_2258Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (326 aa)
Spro_2263TIGRFAM: PTS system, maltose and glucose-specific subfamily, IIC subunit; PTS system, maltose and glucose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE2011 PTS system, maltose and glucose-specific IIAbc component. (474 aa)
Spro_2324PFAM: glycoside hydrolase family 1; KEGG: eca:ECA0859 beta-glucosidase; Belongs to the glycosyl hydrolase 1 family. (470 aa)
Spro_2403PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: stm:STM1567 alcohol dehydrogenase. (337 aa)
Spro_2410PFAM: aldehyde dehydrogenase; KEGG: pae:PA4022 probable aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa)
Spro_2500PFAM: glycoside hydrolase family 1; KEGG: yen:YE1417 6-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family. (478 aa)
Spro_2604PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: yen:YE2102 putative pyruvate-flavodoxin oxidoreductase. (1177 aa)
Spro_2704PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: yen:YE2238 aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (890 aa)
Spro_2728KEGG: ypi:YpsIP31758_1987 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa)
Spro_2729PFAM: Aldose 1-epimerase; KEGG: yps:YPTB2082 hypothetical protein; Belongs to the glucose-6-phosphate 1-epimerase family. (291 aa)
Spro_2770KEGG: eca:ECA2481 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (480 aa)
Spro_3119KEGG: kpn:KPN_01710 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
Spro_3164Glucose-1-phosphatase; PFAM: histidine acid phosphatase; KEGG: ssn:SSON_1012 periplasmic glucose-1-phosphatase. (409 aa)
glkGlucokinase; KEGG: ecv:APECO1_4149 glucokinase; TIGRFAM: glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. (320 aa)
Spro_3450TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: yen:YE1205 PTS system, glucose-specific IIA component. (169 aa)
Spro_3568PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: plu:plu2781 fructose-biphosphate aldolase class I (FBP aldolase). (349 aa)
Spro_3658PFAM: iron-containing alcohol dehydrogenase; KEGG: ent:Ent638_0142 iron-containing alcohol dehydrogenase. (383 aa)
Spro_3867PFAM: aldehyde dehydrogenase; KEGG: ppu:PP_2487 aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (488 aa)
Spro_3944Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: yen:YE3414 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (386 aa)
Spro_4009TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: yen:YE0702 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase complex. (474 aa)
Spro_4010Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (630 aa)
Spro_40112-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa)
Spro_4221Beta-glucosidase; PFAM: glycoside hydrolase family 1; KEGG: kpn:KPN_01961 6-phospho-beta-glucosidase A. (467 aa)
Spro_4225PFAM: Aldose 1-epimerase; KEGG: ecj:JW2528 conserved hypothetical protein. (295 aa)
Spro_4276PFAM: glucose-6-phosphate isomerase; Cupin 2 conserved barrel domain protein; KEGG: aha:AHA_2345 glucose-6-phosphate isomerase. (187 aa)
Spro_4277KEGG: pdi:BDI_3293 putative thermophilic glucose-6-phosphate isomerase-like protein. (260 aa)
Spro_4441PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bvi:Bcep1808_3188 alcohol dehydrogenase, zinc-binding domain protein. (350 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: yen:YE3870 glucose-6-phosphate isomerase; Belongs to the GPI family. (548 aa)
Spro_4591PFAM: glycoside hydrolase family 4; KEGG: ypi:YpsIP31758_3951 6-phospho-beta-glucosidase. (435 aa)
pckA-2Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (539 aa)
Spro_4777PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: ypp:YPDSF_3529 pyridine nucleotide-disulphide oxidoreductase. (482 aa)
Spro_4799TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: yen:YE0098 putative fructose 1,6-bisphosphatase. (336 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (514 aa)
Spro_4879TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yen:YE0030 hypothetical protein. (196 aa)
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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