STRINGSTRING
Spro_0509 Spro_0509 Spro_0584 Spro_0584 Spro_0613 Spro_0613 proB proB proA proA Spro_1619 Spro_1619 Spro_1729 Spro_1729 Spro_1838 Spro_1838 Spro_1840 Spro_1840 Spro_1841 Spro_1841 Spro_1842 Spro_1842 Spro_1843 Spro_1843 Spro_1940 Spro_1940 Spro_2064 Spro_2064 Spro_2065 Spro_2065 Spro_2067 Spro_2067 Spro_2068 Spro_2068 Spro_2482 Spro_2482 astE astE astB astB astD astD astA astA argD argD Spro_2931 Spro_2931 Spro_3024 Spro_3024 Spro_3216 Spro_3216 Spro_3528 Spro_3528 Spro_3641 Spro_3641 patD patD Spro_3647 Spro_3647 Spro_3867 Spro_3867 speB speB speA speA speE speE speD speD proC proC Spro_4047 Spro_4047 Spro_4067 Spro_4067 Spro_4594 Spro_4594 Spro_4710 Spro_4710 Spro_4822 Spro_4822
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Spro_0509PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: yen:YE0455 ornithine decarboxylase, inducible. (723 aa)
Spro_0584PFAM: glutamine synthetase catalytic region; KEGG: kpn:KPN_01021 putative glutamine synthetase. (465 aa)
Spro_0613PFAM: FAD dependent oxidoreductase; KEGG: plu:plu4287 unnamed protein product; highly similar to probable oxidoreductase. (454 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (417 aa)
Spro_1619TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: bmn:BMA10247_A0674 agmatinase; Belongs to the arginase family. (310 aa)
Spro_1729Aspartate transaminase; PFAM: aminotransferase class I and II; KEGG: yen:YE1561 aspartate aminotransferase. (401 aa)
Spro_1838PFAM: dihydrodipicolinate synthetase; KEGG: bch:Bcen2424_4139 dihydrodipicolinate synthetase; Belongs to the DapA family. (306 aa)
Spro_1840PFAM: proline racemase; KEGG: pap:PSPA7_4122 hypothetical protein. (315 aa)
Spro_1841PFAM: FAD dependent oxidoreductase; KEGG: plu:plu2242 hypothetical protein. (374 aa)
Spro_1842PFAM: ferredoxin; KEGG: bam:Bamb_3552 ferredoxin. (84 aa)
Spro_1843PFAM: BFD domain protein [2Fe-2S]-binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bur:Bcep18194_B1891 pyridine nucleotide-disulphide oxidoreductase. (420 aa)
Spro_1940KEGG: ypp:YPDSF_1342 proline iminopeptidase; TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold; Belongs to the peptidase S33 family. (317 aa)
Spro_2064PFAM: FAD dependent oxidoreductase; KEGG: kpn:KPN_01017 probable oxidoreductase. (426 aa)
Spro_2065PFAM: aldehyde dehydrogenase; KEGG: sfv:SFV_1314 aldehyde dehydrogenase, prefers NADP over NAD; Belongs to the aldehyde dehydrogenase family. (498 aa)
Spro_2067Peptidase C26; PFAM: glutamine amidotransferase class-I; peptidase C26; KEGG: kpn:KPN_01020 probable amidotransferase subunit. (253 aa)
Spro_2068Glutamate--putrescine ligase; PFAM: glutamine synthetase catalytic region; KEGG: ecs:ECs1874 putative glutamine synthetase. (472 aa)
Spro_2482Agmatine deiminase; PFAM: Porphyromonas-type peptidyl-arginine deiminase; KEGG: pen:PSEEN4632 peptidylarginine deiminase, PPADH family; Belongs to the agmatine deiminase family. (375 aa)
astESuccinylglutamate desuccinylase/aspartoacylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (327 aa)
astBSuccinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2). (446 aa)
astDAldehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. (490 aa)
astAArginine N-succinyltransferase; Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. (344 aa)
argDAcetylornithine and succinylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (404 aa)
Spro_2931Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. (1323 aa)
Spro_3024PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: stp:Strop_0460 ornithine cyclodeaminase/mu-crystallin. (318 aa)
Spro_3216PFAM: glutamine synthetase catalytic region; KEGG: ecj:JW5201 gamma-Glu-putrescine synthase. (472 aa)
Spro_3528PFAM: GCN5-related N-acetyltransferase; KEGG: ypi:YpsIP31758_1232 spermidine N(1)-acetyltransferase. (184 aa)
Spro_3641KEGG: aha:AHA_2947 twin-arginine translocation pathway signal. (636 aa)
patDAldehyde dehydrogenase; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4- aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (474 aa)
Spro_3647PFAM: aldehyde dehydrogenase; KEGG: pfo:Pfl_1049 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (487 aa)
Spro_3867PFAM: aldehyde dehydrogenase; KEGG: ppu:PP_2487 aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (488 aa)
speBPutative agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily. (306 aa)
speAArginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (658 aa)
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (287 aa)
speDAdenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. (264 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa)
Spro_4047PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: ypp:YPDSF_0554 ornithine decarboxylase. (720 aa)
Spro_4067PFAM: aminotransferase class I and II; KEGG: bha:BH1695 aspartate aminotransferase. (457 aa)
Spro_4594N-isopropylammelide isopropylaminohydrolase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: yen:YE3964 cytosine deaminase. (422 aa)
Spro_4710PFAM: Amidase; KEGG: bte:BTH_II1476 6-aminohexanoate-cyclic-dimer hydrolase; Belongs to the amidase family. (481 aa)
Spro_4822PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sdy:SDY_4094 biodegradative arginine decarboxylase. (761 aa)
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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