STRINGSTRING
Spro_0593 Spro_0593 Spro_0985 Spro_0985 Spro_1170 Spro_1170 hisC hisC Spro_1729 Spro_1729 Spro_1828 Spro_1828 Spro_1832 Spro_1832 Spro_1956 Spro_1956 Spro_2010 Spro_2010 dadA dadA mhpE mhpE mhpF mhpF Spro_3071 Spro_3071 Spro_3072 Spro_3072 Spro_3073 Spro_3073 Spro_3074 Spro_3074 Spro_3075 Spro_3075 Spro_3076 Spro_3076 Spro_3077 Spro_3077 Spro_3078 Spro_3078 Spro_3079 Spro_3079 Spro_3080 Spro_3080 Spro_3081 Spro_3081 Spro_3082 Spro_3082 Spro_3088 Spro_3088 katG katG Spro_3206 Spro_3206 Spro_3963 Spro_3963 Spro_4067 Spro_4067 Spro_4445 Spro_4445 Spro_4654 Spro_4654 Spro_4710 Spro_4710
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Spro_0593PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: kpn:KPN_02056 3-hydroxybutyryl-CoA dehydrogenase. (307 aa)
Spro_0985PFAM: aldehyde dehydrogenase; KEGG: kpn:KPN_01455 phenylacetaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (499 aa)
Spro_1170PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ret:RHE_PD00126 probable aryl-alcohol dehydrogenase protein. (364 aa)
hisCTIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: yen:YE2767 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (362 aa)
Spro_1729Aspartate transaminase; PFAM: aminotransferase class I and II; KEGG: yen:YE1561 aspartate aminotransferase. (401 aa)
Spro_1828PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sma:SAV1350 putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (240 aa)
Spro_1832PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: pin:Ping_0657 3-hydroxybutyryl-CoA dehydrogenase. (509 aa)
Spro_1956PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pap:PSPA7_4414 aryl-alcohol dehydrogenase (benzyl alcoholdehydrogenase) (badh). (365 aa)
Spro_2010PFAM: Malate/L-lactate dehydrogenase; KEGG: ecv:APECO1_1289 hypothetical oxidoreductase; Belongs to the LDH2/MDH2 oxidoreductase family. (362 aa)
dadAD-amino-acid dehydrogenase; Oxidative deamination of D-amino acids; Belongs to the DadA oxidoreductase family. (434 aa)
mhpEPyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (333 aa)
mhpFSemialdehyde dehydrogenase NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (295 aa)
Spro_3071TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: aldehyde dehydrogenase; MaoC domain protein dehydratase; KEGG: kpn:KPN_01468 phenylacetic acid degradation protein; putative aldehyde dehydrogenase. (690 aa)
Spro_3072TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: kpn:KPN_01469 phenylacetic acid degradation protein. (312 aa)
Spro_3073TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit; PFAM: phenylacetic acid degradation B; KEGG: kpn:KPN_01470 phenylacetic acid degradation protein. (96 aa)
Spro_3074TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: kpn:KPN_01471 phenylacetic acid degradation protein. (253 aa)
Spro_3075TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; KEGG: eco:b1391 phenylacetic acid degradation protein. (165 aa)
Spro_3076TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: ecj:JW1387 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation. (352 aa)
Spro_3077PFAM: Enoyl-CoA hydratase/isomerase; KEGG: ecj:JW1388 enoyl-CoA hydratase-isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
Spro_3078TIGRFAM: phenylacetate degradation probable enoyl-CoA hydratase paaB; PFAM: Enoyl-CoA hydratase/isomerase; KEGG: kpn:KPN_01475 enoyl-CoA hydratase. (263 aa)
Spro_3079PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: kpn:KPN_01476 3-hydroxybutyryl-CoA dehydrogenase. (506 aa)
Spro_3080TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein; KEGG: ecj:JW1391 predicted thioesterase. (146 aa)
Spro_3081KEGG: ecj:JW1392 predicted beta-ketoadipyl CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
Spro_3082phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (436 aa)
Spro_3088Aspartate transaminase; PFAM: aminotransferase class I and II; KEGG: aha:AHA_0624 aromatic-amino-acid aminotransferase. (395 aa)
katGCatalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (732 aa)
Spro_3206Amidohydrolase; KEGG: pau:PA14_26260 putative hydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (389 aa)
Spro_3963PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: kpn:KPN_03366 putative ferredoxin reductase subunit. (403 aa)
Spro_4067PFAM: aminotransferase class I and II; KEGG: bha:BH1695 aspartate aminotransferase. (457 aa)
Spro_4445Aromatic-amino-acid transaminase; PFAM: aminotransferase class I and II; KEGG: yps:YPTB0377 aspartate aminotransferase. (397 aa)
Spro_4654PFAM: GCN5-related N-acetyltransferase; KEGG: yen:YE4024 hypothetical protein. (172 aa)
Spro_4710PFAM: Amidase; KEGG: bte:BTH_II1476 6-aminohexanoate-cyclic-dimer hydrolase; Belongs to the amidase family. (481 aa)
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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