node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spro_0377 | Spro_3278 | Spro_0377 | Spro_3278 | PFAM: Catalase domain protein; KEGG: bch:Bcen2424_3898 catalase; Belongs to the catalase family. | PFAM: Catalase domain protein; KEGG: yen:YE1380 catalase; Belongs to the catalase family. | 0.910 |
Spro_0377 | katG | Spro_0377 | Spro_3192 | PFAM: Catalase domain protein; KEGG: bch:Bcen2424_3898 catalase; Belongs to the catalase family. | Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.919 |
Spro_0592 | Spro_1268 | Spro_0592 | Spro_1268 | KEGG: ppu:PP_4636 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.814 |
Spro_0592 | Spro_1828 | Spro_0592 | Spro_1828 | KEGG: ppu:PP_4636 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sma:SAV1350 putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.718 |
Spro_0592 | Spro_3077 | Spro_0592 | Spro_3077 | KEGG: ppu:PP_4636 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: ecj:JW1388 enoyl-CoA hydratase-isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.723 |
Spro_0592 | Spro_4857 | Spro_0592 | Spro_4857 | KEGG: ppu:PP_4636 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | KEGG: mmr:Mmar10_2665 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.916 |
Spro_0592 | fadB | Spro_0592 | Spro_0261 | KEGG: ppu:PP_4636 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.996 |
Spro_0592 | fadJ | Spro_0592 | Spro_3378 | KEGG: ppu:PP_4636 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Fatty acid oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.996 |
Spro_1268 | Spro_0592 | Spro_1268 | Spro_0592 | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | KEGG: ppu:PP_4636 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.814 |
Spro_1268 | Spro_4009 | Spro_1268 | Spro_4009 | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: yen:YE0702 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase complex. | 0.993 |
Spro_1268 | Spro_4777 | Spro_1268 | Spro_4777 | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: ypp:YPDSF_3529 pyridine nucleotide-disulphide oxidoreductase. | 0.978 |
Spro_1268 | Spro_4857 | Spro_1268 | Spro_4857 | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | KEGG: mmr:Mmar10_2665 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.814 |
Spro_1828 | Spro_0592 | Spro_1828 | Spro_0592 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sma:SAV1350 putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | KEGG: ppu:PP_4636 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.718 |
Spro_1828 | Spro_3077 | Spro_1828 | Spro_3077 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sma:SAV1350 putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: ecj:JW1388 enoyl-CoA hydratase-isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.919 |
Spro_1828 | Spro_4857 | Spro_1828 | Spro_4857 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sma:SAV1350 putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | KEGG: mmr:Mmar10_2665 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.723 |
Spro_1828 | fadB | Spro_1828 | Spro_0261 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sma:SAV1350 putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.942 |
Spro_1828 | fadJ | Spro_1828 | Spro_3378 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sma:SAV1350 putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Fatty acid oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.945 |
Spro_2366 | Spro_3090 | Spro_2366 | Spro_3090 | KEGG: bpe:BP0300 putative esterase. | KEGG: pde:Pden_5100 esterase/lipase-like protein. | 0.921 |
Spro_2366 | kynA | Spro_2366 | Spro_3022 | KEGG: bpe:BP0300 putative esterase. | Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.916 |
Spro_3077 | Spro_0592 | Spro_3077 | Spro_0592 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: ecj:JW1388 enoyl-CoA hydratase-isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. | KEGG: ppu:PP_4636 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.723 |