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glmU glmU glmS glmS Spro_0137 Spro_0137 wecB wecB wecC wecC murB murB glmM glmM Spro_0536 Spro_0536 Spro_1036 Spro_1036 Spro_1161 Spro_1161 Spro_1223 Spro_1223 Spro_1226 Spro_1226 nagB nagB Spro_1228 Spro_1228 Spro_1232 Spro_1232 Spro_1234 Spro_1234 Spro_1241 Spro_1241 galK galK Spro_1292 Spro_1292 Spro_1581 Spro_1581 Spro_1582 Spro_1582 Spro_1599 Spro_1599 Spro_1600 Spro_1600 Spro_1601 Spro_1601 Spro_1914 Spro_1914 nagZ nagZ nagK nagK arnB arnB arnC arnC arnA arnA arnD arnD Spro_2263 Spro_2263 Spro_2277 Spro_2277 Spro_2576 Spro_2576 Spro_2707 Spro_2707 Spro_2708 Spro_2708 Spro_2709 Spro_2709 Spro_2725 Spro_2725 Spro_2813 Spro_2813 Spro_2814 Spro_2814 Spro_2815 Spro_2815 glk glk Spro_3450 Spro_3450 Spro_3476 Spro_3476 murQ murQ Spro_4203 Spro_4203 Spro_4276 Spro_4276 Spro_4277 Spro_4277 Spro_4279 Spro_4279 Spro_4280 Spro_4280 Spro_4281 Spro_4281 murA murA pgi pgi glgC glgC
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (456 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
Spro_0137Chitinase; KEGG: sbl:Sbal_3083 chitinase; PFAM: glycoside hydrolase family 18; Chitinase A domain protein; SMART: PKD domain containing protein; chitinase II; Belongs to the glycosyl hydrolase 18 family. (563 aa)
wecBUDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. (376 aa)
wecCUDP-glucose/GDP-mannose dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (345 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (445 aa)
Spro_0536PFAM: Beta-N-acetylhexosaminidase-like; Glycoside hydrolase, family 20, catalytic core; KEGG: ent:Ent638_0442 beta-N-acetylhexosaminidase. (797 aa)
Spro_1036PFAM: ROK family protein; KEGG: kpn:KPN_00337 possible NAGC-like transcriptional regulator. (302 aa)
Spro_1161TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KR domain protein; KEGG: plu:plu4831 UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase). (338 aa)
Spro_1223PFAM: glycoside hydrolase family 18; Carbohydrate-binding family V/XII; Fibronectin type III domain protein; KEGG: pfl:PFL_2091 chitinase; Belongs to the glycosyl hydrolase 18 family. (484 aa)
Spro_1226KEGG: yen:YE2980 putative N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase. (379 aa)
nagBGlucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (266 aa)
Spro_1228TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: stm:STM0685 Sugar Specific PTS family, n-acetylglucosamine-specific enzyme IIABC. (648 aa)
Spro_1232Beta-N-acetylhexosaminidase; PFAM: Carbohydrate-binding chitobiase/hexosaminidase-type domain protein; glycoside hydrolase family 20 domain protein; Beta-N-acetylhexosaminidase-like; Glycoside hydrolase, family 20, catalytic core; KEGG: yen:YE2974 chitobiase precursor. (885 aa)
Spro_1234TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: plu:plu4831 UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase). (350 aa)
Spro_1241TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: yen:YE2967 phosphoglucomutase. (547 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (383 aa)
Spro_1292KEGG: kpn:KPN_00772 galactose-1-phosphate uridylyltransferase; TIGRFAM: galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein. (350 aa)
Spro_1581TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: yen:YE2778 UTP-glucose-1-phosphate uridylyltransferase. (304 aa)
Spro_1582TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: yen:YE2777 UTP-glucose-1-phosphate uridylyltransferase. (297 aa)
Spro_1599KEGG: eca:ECA1438 mannose-1-phosphate guanylyltransferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. (474 aa)
Spro_1600Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: ent:Ent638_2662 phosphomannomutase. (455 aa)
Spro_1601TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KR domain protein; KEGG: plu:plu4831 UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase). (337 aa)
Spro_1914TIGRFAM: PTS system, maltose and glucose-specific subfamily, IIC subunit; PTS system, glucose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE1643 PTS system, glucose-specific IIBC component. (477 aa)
nagZGlycoside hydrolase family 3 domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (339 aa)
nagKROK family protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. (306 aa)
arnBDegT/DnrJ/EryC1/StrS aminotransferase; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. (384 aa)
arnCGlycosyl transferase family 2; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. (326 aa)
arnANAD-dependent epimerase/dehydratase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. (660 aa)
arnDPolysaccharide deacetylase; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily. (301 aa)
Spro_2263TIGRFAM: PTS system, maltose and glucose-specific subfamily, IIC subunit; PTS system, maltose and glucose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE2011 PTS system, maltose and glucose-specific IIAbc component. (474 aa)
Spro_2277TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; KEGG: yen:YE2015 mannose-6-phosphate isomerase. (392 aa)
Spro_2576PFAM: ROK family protein; KEGG: pin:Ping_1332 ROK family protein. (307 aa)
Spro_2707PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: kpn:KPN_02492 uridine diphosphate galacturonate 4-epimerase. (336 aa)
Spro_2708PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: sgl:SG1368 putative UDP-glucose dehydrogenase. (447 aa)
Spro_2709TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: eca:ECA2329 UTP--glucose-1-phosphate uridylyltransferase. (305 aa)
Spro_2725PFAM: glycoside hydrolase family 18; SMART: chitinase II; KEGG: kpn:KPN_01201 putative chitinase II; Belongs to the glycosyl hydrolase 18 family. (426 aa)
Spro_2813KEGG: yps:YPTB1634 PTS system, mannose-specific IIAB component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PTS system, mannose/fructose/sorbose family, IIA subunit; PFAM: PTS system fructose subfamily IIA component; PTS system sorbose subfamily IIB component. (323 aa)
Spro_2814TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: ypi:YpsIP31758_2369 PTS system, mannose/fructose/sorbose family, IIC component. (266 aa)
Spro_2815TIGRFAM: PTS system, mannose/fructose/sorbose family, IID subunit; PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: sgl:SG1325 PTS system mannose-specific IID component ManZ. (280 aa)
glkGlucokinase; KEGG: ecv:APECO1_4149 glucokinase; TIGRFAM: glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. (320 aa)
Spro_3450TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: yen:YE1205 PTS system, glucose-specific IIA component. (169 aa)
Spro_3476Chitinase; KEGG: sde:Sde_3870 chitinase; PFAM: glycoside hydrolase family 18; Carbohydrate-binding family V/XII; SMART: chitinase II; Belongs to the glycosyl hydrolase 18 family. (499 aa)
murQGlucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. (297 aa)
Spro_4203PFAM: PfkB domain protein; KEGG: yen:YE0554 fructokinase; Belongs to the carbohydrate kinase PfkB family. (309 aa)
Spro_4276PFAM: glucose-6-phosphate isomerase; Cupin 2 conserved barrel domain protein; KEGG: aha:AHA_2345 glucose-6-phosphate isomerase. (187 aa)
Spro_4277KEGG: pdi:BDI_3293 putative thermophilic glucose-6-phosphate isomerase-like protein. (260 aa)
Spro_4279PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: aha:AHA_2340 PTS system, fructose(mannose)-specific IIC. (266 aa)
Spro_4280PFAM: PTS system sorbose subfamily IIB component; KEGG: aha:AHA_2341 PTS system mannose-specific EIIAB component (EIIAB-man). (164 aa)
Spro_4281PFAM: PTS system fructose subfamily IIA component; KEGG: aha:AHA_2342 PTS system, mannose/fructose/sorbose family, IIA component. (142 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: yen:YE3870 glucose-6-phosphate isomerase; Belongs to the GPI family. (548 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (425 aa)
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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