(139 nodes) rRNA processing network (Ceraceosorus bombacis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A0N7L8U3	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. (652 aa)
	A0A0N7L8W8	EXOSOME COMPLEX EXONUCLEASE (RIBOSOMAL RNA PROCESSING PROTEIN). (375 aa)
	A0A0N7L970	Probable rok1-atp-dependent rna helicase; Belongs to the DEAD box helicase family. (582 aa)
	A0A0N7L9D0	Uncharacterized conserved protein. (406 aa)
	A0A0N7L9E5	WD40 repeat protein. (1079 aa)
	A0A0N7L9I3	Brix-domain-containing protein. (300 aa)
	A0A0N7LA62	C1D, LRP1. (312 aa)
	A0A0N7LAE7	Exosomal 3'-5' exoribonuclease complex, subunit Rrp41 and related exoribonucleases. (285 aa)
	A0A0N7LAE9	Nucleolar protein fibrillarin NOP77 (RRM superfamily). (1103 aa)
	A0A0N7LAF6	P-loop containing nucleoside triphosphate hydrolase protein. (108 aa)
	A0A0N7LAJ7	Dual specificity phosphatase. (604 aa)
	A0A0N7LAK2	Predicted nucleolar protein involved in ribosome biogenesis. (788 aa)
	A0A0N7LAZ5	Uncharacterized conserved protein. (1430 aa)
	A0A0N7LBE0	Uncharacterized protein. (388 aa)
	A0A0N7LBI8	Exosomal 3'-5' exoribonuclease complex, subunit Rrp4. (390 aa)
	A0A0P1B7I2	Exosomal 3'-5' exoribonuclease complex, subunit Rrp43. (380 aa)
	A0A0P1B7Y5	Uncharacterized conserved protein. (1546 aa)
	A0A0P1B8B6	Predicted RNA-binding protein, contains Pumilio domains. (819 aa)
	A0A0P1B8G5	Protein involved in rRNA processing. (338 aa)
	A0A0P1B8S3	Ribosomal rna assembly protein mis3. (708 aa)
	A0A0P1B9C5	U3 small nucleolar RNA-associated protein 22. (1115 aa)
	A0A0P1B9G1	Microtubule binding protein ytm1. (531 aa)
	A0A0P1B9P1	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (547 aa)
	A0A0P1B9U7	Uncharacterized protein family UPF0642. (133 aa)
	A0A0P1BA18	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. (1511 aa)
	SPB1	AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (929 aa)
	A0A0P1BA35	Duf663-domain-containing protein. (965 aa)
	A0A0P1BA52	Protein required for biogenesis of the ribosomal 60S subunit. (371 aa)
	A0A0P1BAC2	Cell adhesion complex protein bystin. (534 aa)
	A0A0P1BAH4	GTPase. (709 aa)
	A0A0P1BAI7	UTP4, CIRH1A. (130 aa)
	A0A0P1BAM7	ATP-dependent RNA helicase pitchoune. (633 aa)
	A0A0P1BAX6	Atp-dependent rna helicase dbp9. (655 aa)
	A0A0P1BB61	Apoptosis antagonizing transcription factor/protein transport protein. (534 aa)
	A0A0P1BBD8	Nucleolar protein involved in 40S ribosome biogenesis. (990 aa)
	A0A0P1BBU2	Bud site selection-related protein. (190 aa)
	A0A0P1BBW3	Pre-rrna-processing protein pno1. (314 aa)
	A0A0P1BBZ8	ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (792 aa)
	A0A0P1BCI2	Uncharacterized conserved protein. (733 aa)
	A0A0P1BCR6	PROTEIN TMA23. (223 aa)
	A0A0P1BCT4	Atp-dependent rrna helicase rrp3; Belongs to the DEAD box helicase family. (537 aa)
	A0A0P1BCT5	Tgf beta-inducible nuclear protein 1. (254 aa)
	A0A0P1BCU8	Uncharacterized protein. (1644 aa)
	A0A0P1BCZ7	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (322 aa)
	A0A0P1BD09	DEAH-box RNA helicase. (998 aa)
	A0A0P1BD53	rRNA processing protein Rrp5. (1672 aa)
	A0A0P1BDE9	Nop-domain-containing protein. (790 aa)
	A0A0P1BDG0	Nucleolus protein. (558 aa)
	A0A0P1BDX8	HAT (Half-A-TPR) repeat-containing protein. (917 aa)
	A0A0P1BE08	Uncharacterized protein. (349 aa)
	A0A0P1BE96	Atp-dependent rna helicase dbp3; Belongs to the DEAD box helicase family. (661 aa)
	A0A0P1BEI8	Exosomal 3'-5' exoribonuclease complex, subunit Rrp45. (336 aa)
	A0A0P1BEQ3	Ribosome biogenesis protein brx1. (311 aa)
	A0A0P1BEQ7	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (358 aa)
	A0A0P1BER3	E3 ubiquitin ligase interacting with arginine methyltransferase. (413 aa)
	A0A0P1BEU3	RNA helicase. (980 aa)
	A0A0P1BEZ3	Nucleolar protein NOP52/RRP1. (387 aa)
	A0A0P1BF52	rRNA processing protein RRP7. (409 aa)
	A0A0P1BF56	Atp-dependent rna helicase; Belongs to the DEAD box helicase family. (402 aa)
	A0A0P1BFA8	Nuclear exosomal rna helicase mtr4. (577 aa)
	A0A0P1BFE2	Protein involved in the nuclear export of pre-ribosomes. (1021 aa)
	A0A0P1BFX0	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (90 aa)
	A0A0P1BFY5	Disrupter of silencing SAS10. (769 aa)
	A0A0P1BFZ7	Antiviral helicase. (586 aa)
	A0A0P1BG43	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (865 aa)
	A0A0P1BG44	WD40 repeat-containing protein. (527 aa)
	A0A0P1BG97	RNA helicase. (820 aa)
	A0A0P1BGB6	Related to nop15-protein involved in 60s ribosomal subunit biogenesis. (384 aa)
	A0A0P1BGH4	GTPase. (819 aa)
	A0A0P1BGQ3	TBP-binding protein, activator of basal transcription (Contains rrm motif). (225 aa)
	A0A0P1BGU7	Fcf1-domain-containing protein. (205 aa)
	A0A0P1BH48	Nop domain-containing protein. (590 aa)
	A0A0P1BH56	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (384 aa)
	A0A0P1BH65	RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains. (1208 aa)
	A0A0P1BH66	Proliferation-associated nucleolar protein (NOL1); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (775 aa)
	A0A0P1BH81	WD40/YVTN repeat-like-containing domain. (519 aa)
	A0A0P1BH92	Ribosome Assembly protein. (541 aa)
	A0A0P1BHD7	Dead-domain-containing protein. (904 aa)
	A0A0P1BHL2	Conserved WD40 repeat-containing protein. (601 aa)
	A0A0P1BHN4	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (687 aa)
	A0A0P1BHQ7	Nucleolar protein (NOP16) involved in 60S ribosomal subunit biogenesis. (275 aa)
	A0A0P1BHS1	Exosomal 3'-5' exoribonuclease complex, subunit ski4 (Csl4). (237 aa)
	A0A0P1BI77	60s ribosomal protein L30 isolog. (166 aa)
	A0A0P1BIC5	Sof1-like rRNA processing protein (Contains WD40 repeats). (508 aa)
	A0A0P1BID2	WD40-repeat-containing subunit of the 18S rRNA processing complex. (1057 aa)
	A0A0P1BIL7	Uncharacterized conserved protein. (207 aa)
	A0A0P1BIN8	Exosomal 3'-5' exoribonuclease complex, subunit Rrp46. (283 aa)
	A0A0P1BIX0	Uncharacterized protein. (173 aa)
	A0A0P1BJ07	Rna exonuclease 4. (414 aa)
	A0A0P1BJ39	Protein MAK16; Belongs to the MAK16 family. (369 aa)
	A0A0P1BJ60	Uncharacterized protein. (327 aa)
	TIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (245 aa)
	A0A0P1BJ92	Protein involved in high osmolarity signaling pathway. (902 aa)
	A0A0P1BJE4	Uncharacterized conserved protein. (1658 aa)
	A0A0P1BJE5	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
	A0A0P1BJK6	Related to emg1-protein required for ribosome biogenesis. (395 aa)
	A0A0P1BJU1	Small nucleolar ribonucleoprotein complex subunit utp14. (323 aa)
	A0A0P1BK21	Exosomal 3'-5' exoribonuclease complex, subunit Rrp41 and related exoribonucleases. (313 aa)
	NOP7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (742 aa)
	A0A0P1BKB8	Uncharacterized conserved protein. (909 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1146 aa)
	A0A0P1BKK1	UNCHARACTERIZED. (367 aa)
	A0A0P1BKQ7	Related to rio2 protein. (620 aa)
	A0A0P1BKS2	U3 snoRNP-associated protein (Contains WD40 repeats). (707 aa)
	A0A0P1BKW8	Uncharacterized protein. (930 aa)
	A0A0P1BKY9	Uncharacterized conserved protein. (213 aa)
	A0A0P1BL58	Uncharacterized protein. (302 aa)
	A0A0P1BL98	RNA 3'-terminal phosphate cyclase. (413 aa)
	A0A0P1BLE4	Uncharacterized protein. (388 aa)
	A0A0P1BLN4	Uncharacterized proteins of PilT N-term./Vapc superfamily. (283 aa)
	A0A0P1BLQ1	NMD protein affecting ribosome stability and mRNA decay. (1099 aa)
	A0A0P1BM15	DRIM (Down-regulated in metastasis)-like proteins. (2860 aa)
	A0A0P1BM90	WD repeat protein. (1263 aa)
	A0A0P1BMF2	Nuclear localization sequence binding protein. (558 aa)
	A0A0P1BMS8	Alpha-l rna-binding motif-containing protein. (182 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (871 aa)
	A0A0P1BND1	RNA-binding protein (RRM superfamily). (1027 aa)
	A0A0P1BNE5	Predicted GTP-binding protein MMR1. (706 aa)
	A0A0P1BNH0	Atp-dependent rna helicase a. (1512 aa)
	A0A0P1BNP5	Uncharacterized conserved protein. (363 aa)
	A0A0P1BPA2	P-loop containing nucleoside triphosphate hydrolase protein. (1483 aa)
	A0A0P1BPG0	Uncharacterized protein. (738 aa)
	A0A0P1BPL6	RNA helicase. (833 aa)
	A0A0P1BPY7	ATP-dependent RNA helicase DBP10. (1044 aa)
	A0A0P1BQ87	WD40 repeat protein. (648 aa)
	A0A0P1BQG0	WD40-repeat-containing subunit of the 18S rRNA processing complex. (926 aa)
	A0A0P1BQN7	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (664 aa)
	A0A0P1BQR0	Rio1-domain-containing protein. (782 aa)
	A0A0P1BQU3	Atp-dependent rna helicase has1; Belongs to the DEAD box helicase family. (521 aa)
	A0A0P1BRB1	Exosomal 3'-5' exoribonuclease complex subunit Rrp40. (253 aa)
	A0A0P1BRJ8	Exosomal 3-5 exoribonuclease subunit rrp44 dis3. (862 aa)
	A0A0P1BRU1	Probable nop2-nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (751 aa)
	A0A0P1BRU2	WD40-repeat-containing subunit of the 18S rRNA processing complex. (674 aa)
	A0A0P1BRZ3	Uncharacterized protein. (347 aa)
	A0A0P1BS45	Nucleolar protein-like/EBNA1-binding protein. (216 aa)
	A0A0P1BT07	C2H2-type Zn-finger protein. (445 aa)
	A0A0P1BTD9	Predicted regulator of rRNA gene transcription (MYB-binding protein). (1331 aa)
	A0A0P1BTV8	Dead-domain-containing protein. (755 aa)
	A0A0P1BU11	Ribosome biogenesis protein RPF1, contains IMP4 domain. (438 aa)

Your Current Organism:

Ceraceosorus bombacis

NCBI taxonomy Id: 401625
Other names: ATCC 22867, C. bombacis, Dicellomyces bombacis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0N7L8U3	A0A0N7L8W8	A0A0N7L8U3	A0A0N7L8W8	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	EXOSOME COMPLEX EXONUCLEASE (RIBOSOMAL RNA PROCESSING PROTEIN).	0.669
A0A0N7L8U3	A0A0N7L970	A0A0N7L8U3	A0A0N7L970	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Probable rok1-atp-dependent rna helicase; Belongs to the DEAD box helicase family.	0.882
A0A0N7L8U3	A0A0N7L9D0	A0A0N7L8U3	A0A0N7L9D0	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Uncharacterized conserved protein.	0.989
A0A0N7L8U3	A0A0N7L9E5	A0A0N7L8U3	A0A0N7L9E5	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	WD40 repeat protein.	0.861
A0A0N7L8U3	A0A0N7L9I3	A0A0N7L8U3	A0A0N7L9I3	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Brix-domain-containing protein.	0.961
A0A0N7L8U3	A0A0N7LA62	A0A0N7L8U3	A0A0N7LA62	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	C1D, LRP1.	0.673
A0A0N7L8U3	A0A0N7LAE7	A0A0N7L8U3	A0A0N7LAE7	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Exosomal 3'-5' exoribonuclease complex, subunit Rrp41 and related exoribonucleases.	0.660
A0A0N7L8U3	A0A0N7LAE9	A0A0N7L8U3	A0A0N7LAE9	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Nucleolar protein fibrillarin NOP77 (RRM superfamily).	0.589
A0A0N7L8U3	A0A0N7LAF6	A0A0N7L8U3	A0A0N7LAF6	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	P-loop containing nucleoside triphosphate hydrolase protein.	0.699
A0A0N7L8U3	A0A0N7LAK2	A0A0N7L8U3	A0A0N7LAK2	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Predicted nucleolar protein involved in ribosome biogenesis.	0.891
A0A0N7L8U3	A0A0N7LAZ5	A0A0N7L8U3	A0A0N7LAZ5	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Uncharacterized conserved protein.	0.537
A0A0N7L8U3	A0A0N7LBI8	A0A0N7L8U3	A0A0N7LBI8	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Exosomal 3'-5' exoribonuclease complex, subunit Rrp4.	0.683
A0A0N7L8U3	A0A0P1B7I2	A0A0N7L8U3	A0A0P1B7I2	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Exosomal 3'-5' exoribonuclease complex, subunit Rrp43.	0.698
A0A0N7L8U3	A0A0P1B7Y5	A0A0N7L8U3	A0A0P1B7Y5	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Uncharacterized conserved protein.	0.871
A0A0N7L8U3	A0A0P1B8B6	A0A0N7L8U3	A0A0P1B8B6	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Predicted RNA-binding protein, contains Pumilio domains.	0.577
A0A0N7L8U3	A0A0P1B8G5	A0A0N7L8U3	A0A0P1B8G5	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Protein involved in rRNA processing.	0.986
A0A0N7L8U3	A0A0P1B8S3	A0A0N7L8U3	A0A0P1B8S3	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Ribosomal rna assembly protein mis3.	0.874
A0A0N7L8U3	A0A0P1B9C5	A0A0N7L8U3	A0A0P1B9C5	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	U3 small nucleolar RNA-associated protein 22.	0.994
A0A0N7L8U3	A0A0P1B9G1	A0A0N7L8U3	A0A0P1B9G1	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	Microtubule binding protein ytm1.	0.625
A0A0N7L8U3	A0A0P1B9P1	A0A0N7L8U3	A0A0P1B9P1	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	0.496