(97 nodes) Histidine kinase/HSP90-like ATPase network (Lechevalieria xinjiangensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SEP95182.1	Signal transduction histidine kinase. (424 aa)
	SEP66166.1	Two-component system, LytT family, sensor kinase. (420 aa)
	gyrB	DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (656 aa)
	SEP70511.1	Signal transduction histidine kinase. (389 aa)
	SEP72353.1	Signal transduction histidine kinase. (384 aa)
	SEP78411.1	Sensor histidine kinase regulating citrate/malate metabolism. (512 aa)
	SEP82713.1	Two-component system, OmpR family, sensor histidine kinase SenX3. (390 aa)
	SEP64739.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (368 aa)
	SEP90339.1	Phage shock protein C (PspC) family protein. (392 aa)
	SEQ08548.1	Signal transduction histidine kinase. (396 aa)
	SEQ15315.1	Signal transduction histidine kinase. (419 aa)
	SEQ20496.1	His Kinase A (phospho-acceptor) domain-containing protein. (300 aa)
	SEQ20805.1	Two-component system, OmpR family, sensor histidine kinase MprB. (461 aa)
	SEQ23019.1	Signal transduction histidine kinase. (351 aa)
	SEQ23329.1	Signal transduction histidine kinase. (380 aa)
	SEQ25019.1	Signal transduction histidine kinase. (1105 aa)
	SEQ25353.1	Two-component system, OmpR family, sensor histidine kinase MtrB. (458 aa)
	SEQ28261.1	Two-component system, OmpR family, sensor kinase. (490 aa)
	SEQ35529.1	Histidine kinase. (407 aa)
	SEQ10847.1	Signal transduction histidine kinase. (422 aa)
	SEQ47516.1	Signal transduction histidine kinase. (357 aa)
	SEQ48022.1	Two-component system, CitB family, sensor kinase. (523 aa)
	SEQ43405.1	Molecular chaperone HtpG. (594 aa)
	SEQ50470.1	Signal transduction histidine kinase. (457 aa)
	SEQ69211.1	Signal transduction histidine kinase. (461 aa)
	SEQ72211.1	Hypothetical protein. (375 aa)
	SEQ80759.1	Signal transduction histidine kinase. (823 aa)
	SEQ81241.1	Signal transduction histidine kinase. (418 aa)
	SEQ82127.1	DNA-binding transcriptional regulator, LacI/PurR family. (1005 aa)
	SEQ90903.1	Anti-sigma regulatory factor (Ser/Thr protein kinase). (146 aa)
	SEQ90982.1	Serine/threonine-protein kinase RsbT. (137 aa)
	SEQ91004.1	Anti-sigma regulatory factor (Ser/Thr protein kinase). (345 aa)
	SEQ91027.1	Signal transduction histidine kinase. (576 aa)
	SEQ91078.1	Histidine kinase-like ATPase domain-containing protein. (126 aa)
	SEQ91105.1	Anti-anti-sigma factor. (869 aa)
	SEQ92032.1	PAS/PAC sensor hybrid histidine kinase. (1413 aa)
	SEQ92754.1	HAMP domain-containing protein. (513 aa)
	SEQ87174.1	Signal transduction histidine kinase. (459 aa)
	SEQ93629.1	GAF sensor hybrid histidine kinase. (1509 aa)
	SEQ86704.1	Signal transduction histidine kinase. (454 aa)
	SEQ99767.1	Anti-sigma regulatory factor (Ser/Thr protein kinase). (147 aa)
	SER00709.1	Signal transduction histidine kinase. (557 aa)
	SER19005.1	Histidine kinase-like ATPase domain-containing protein. (131 aa)
	SER23999.1	PAS domain S-box-containing protein. (341 aa)
	SER25161.1	His Kinase A (phospho-acceptor) domain-containing protein. (332 aa)
	SER25915.1	Signal transduction histidine kinase. (373 aa)
	SER27276.1	Two-component sensor histidine kinase, contains HisKA and HATPase domains. (456 aa)
	SER27759.1	Two-component system, OmpR family, sensor histidine kinase MtrB. (585 aa)
	SER34694.1	Two-component system, OmpR family, sensor histidine kinase MprB. (453 aa)
	SER44313.1	Two-component system, OmpR family, sensor kinase. (463 aa)
	SER45766.1	Anti-sigma regulatory factor (Ser/Thr protein kinase). (307 aa)
	SER46144.1	Anti-sigma regulatory factor (Ser/Thr protein kinase). (134 aa)
	SER46262.1	Signal transduction histidine kinase. (481 aa)
	SER40398.1	Signal transduction histidine kinase. (923 aa)
	SER41851.1	Serine/threonine-protein kinase RsbW. (144 aa)
	SER41873.1	Anti-sigma regulatory factor (Ser/Thr protein kinase). (220 aa)
	SER54673.1	Two-component system, OmpR family, sensor histidine kinase KdpD. (829 aa)
	SER50252.1	GAF domain-containing protein. (503 aa)
	SER62094.1	Signal transduction histidine kinase. (553 aa)
	SER62929.1	HAMP domain-containing protein. (506 aa)
	SER59261.1	DNA gyrase subunit B. (683 aa)
	SER63841.1	Histidine kinase-like ATPase domain-containing protein. (298 aa)
	SER60109.1	Signal transduction histidine kinase. (1382 aa)
	SER60150.1	Anti-sigma regulatory factor (Ser/Thr protein kinase). (131 aa)
	SER60364.1	Signal transduction histidine kinase. (421 aa)
	htpG	Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. (614 aa)
	SER74932.1	Signal transduction histidine kinase. (374 aa)
	SER75519.1	Two-component system, NarL family, sensor histidine kinase DesK. (354 aa)
	SER76089.1	Signal transduction histidine kinase. (455 aa)
	SER76634.1	Histidine kinase-like ATPase domain-containing protein. (108 aa)
	SER84494.1	Two-component system, OmpR family, sensor histidine kinase MtrB. (448 aa)
	SER85650.1	Two-component system, LytT family, sensor kinase. (391 aa)
	SER82247.1	Signal transduction histidine kinase. (434 aa)
	SER92248.1	Signal transduction histidine kinase. (386 aa)
	SER92620.1	Signal transduction histidine kinase. (779 aa)
	SER89633.1	Two-component system, OmpR family, sensor histidine kinase MprB. (477 aa)
	SES01484.1	Histidine kinase. (379 aa)
	SER99601.1	Two-component system, OmpR family, sensor histidine kinase BaeS. (599 aa)
	SES00198.1	Anti-sigma regulatory factor (Ser/Thr protein kinase). (194 aa)
	SES04809.1	DNA-binding transcriptional regulator, LacI/PurR family. (937 aa)
	SES05179.1	Signal transduction histidine kinase. (871 aa)
	SES06964.1	Two-component system, OmpR family, sensor kinase. (490 aa)
	SES07091.1	Two-component system, OmpR family, sensor histidine kinase MtrB. (471 aa)
	SES07821.1	Signal transduction histidine kinase. (346 aa)
	SES10861.1	Signal transduction histidine kinase. (689 aa)
	SES11533.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (624 aa)
	SES15022.1	Signal transduction histidine kinase. (368 aa)
	SES16027.1	Signal transduction histidine kinase. (416 aa)
	SES16558.1	Anti-sigma regulatory factor (Ser/Thr protein kinase). (314 aa)
	SES18117.1	Two-component system, OmpR family, sensor histidine kinase BaeS. (580 aa)
	SES20648.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (360 aa)
	SES23164.1	Anti-sigma regulatory factor (Ser/Thr protein kinase). (306 aa)
	SES25220.1	Anti-sigma regulatory factor (Ser/Thr protein kinase). (130 aa)
	SES29028.1	Signal transduction histidine kinase. (879 aa)
	SES33611.1	Cyclic nucleotide-binding domain-containing protein. (470 aa)
	SES36426.1	Signal transduction histidine kinase. (440 aa)
	SES37245.1	Anti-sigma regulatory factor (Ser/Thr protein kinase). (153 aa)

Your Current Organism:

Lechevalieria xinjiangensis

NCBI taxonomy Id: 402600
Other names: CGMCC 4.3525, DSM 45081, JCM 15473, L. xinjiangensis, Lechevalieria xinjiangensis Wang et al. 2007, strain R24

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SEP64739.1	SEQ23019.1	SAMN05216188_10164	SAMN05216188_102484	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Signal transduction histidine kinase.	0.734
SEP64739.1	SEQ47516.1	SAMN05216188_10164	SAMN05216188_103153	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Signal transduction histidine kinase.	0.605
SEP64739.1	SEQ81241.1	SAMN05216188_10164	SAMN05216188_105196	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Signal transduction histidine kinase.	0.457
SEP64739.1	SEQ82127.1	SAMN05216188_10164	SAMN05216188_105224	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	DNA-binding transcriptional regulator, LacI/PurR family.	0.968
SEP64739.1	SEQ91105.1	SAMN05216188_10164	SAMN05216188_106178	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Anti-anti-sigma factor.	0.902
SEP64739.1	SEQ92032.1	SAMN05216188_10164	SAMN05216188_106217	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	PAS/PAC sensor hybrid histidine kinase.	0.974
SEP64739.1	SEQ92754.1	SAMN05216188_10164	SAMN05216188_106243	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	HAMP domain-containing protein.	0.712
SEP64739.1	SER00709.1	SAMN05216188_10164	SAMN05216188_10751	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Signal transduction histidine kinase.	0.400
SEP64739.1	SER23999.1	SAMN05216188_10164	SAMN05216188_109101	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	PAS domain S-box-containing protein.	0.771
SEP64739.1	SER25915.1	SAMN05216188_10164	SAMN05216188_109189	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Signal transduction histidine kinase.	0.625
SEP64739.1	SER50252.1	SAMN05216188_10164	SAMN05216188_11227	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	GAF domain-containing protein.	0.418
SEP64739.1	SER54673.1	SAMN05216188_10164	SAMN05216188_112195	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Two-component system, OmpR family, sensor histidine kinase KdpD.	0.457
SEP64739.1	SER60109.1	SAMN05216188_10164	SAMN05216188_11352	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Signal transduction histidine kinase.	0.974
SEP64739.1	SER62094.1	SAMN05216188_10164	SAMN05216188_113123	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Signal transduction histidine kinase.	0.407
SEP64739.1	SER62929.1	SAMN05216188_10164	SAMN05216188_113152	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	HAMP domain-containing protein.	0.712
SEP64739.1	SES01484.1	SAMN05216188_10164	SAMN05216188_119115	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Histidine kinase.	0.437
SEP64739.1	SES04809.1	SAMN05216188_10164	SAMN05216188_120103	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	DNA-binding transcriptional regulator, LacI/PurR family.	0.837
SEP64739.1	SES10861.1	SAMN05216188_10164	SAMN05216188_12233	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Signal transduction histidine kinase.	0.457
SEP64739.1	SES15022.1	SAMN05216188_10164	SAMN05216188_12372	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Signal transduction histidine kinase.	0.451
SEP64739.1	SES20648.1	SAMN05216188_10164	SAMN05216188_12640	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	0.411