STRINGSTRING
Rpic_0069 Rpic_0069 bioB bioB Rpic_0185 Rpic_0185 Rpic_0205 Rpic_0205 erpA erpA iscS iscS Rpic_0886 Rpic_0886 Rpic_0890 Rpic_0890 Rpic_0908 Rpic_0908 Rpic_1354 Rpic_1354 Rpic_1364 Rpic_1364 Rpic_1366 Rpic_1366 Rpic_1794 Rpic_1794 Rpic_2054 Rpic_2054 Rpic_2091 Rpic_2091 Rpic_2148 Rpic_2148 Rpic_2157 Rpic_2157 Rpic_2208 Rpic_2208 Rpic_2210 Rpic_2210 Rpic_2246 Rpic_2246 Rpic_2429 Rpic_2429 Rpic_2513 Rpic_2513 ilvD ilvD ilvD-2 ilvD-2 Rpic_2702 Rpic_2702 Rpic_3005 Rpic_3005 Rpic_3150 Rpic_3150 Rpic_3158 Rpic_3158 Rpic_3206 Rpic_3206 Rpic_3232 Rpic_3232 Rpic_3376 Rpic_3376 Rpic_4082 Rpic_4082 Rpic_4165 Rpic_4165 Rpic_4286 Rpic_4286 Rpic_4359 Rpic_4359 Rpic_4510 Rpic_4510 Rpic_4563 Rpic_4563 Rpic_4625 Rpic_4625 Rpic_4626 Rpic_4626 Rpic_4634 Rpic_4634 Rpic_4637 Rpic_4637 Rpic_4805 Rpic_4805
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rpic_0069PFAM: Hemerythrin HHE cation binding domain protein; KEGG: azo:azo0331 hypothetical protein. (158 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (359 aa)
Rpic_0185KEGG: rso:RSc0329 putative ferredoxin 2Fe-2S protein. (109 aa)
Rpic_0205PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: rso:RSc0349 putative bacterioferritin-associated ferredoxin protein. (91 aa)
erpAIron-sulfur cluster assembly accessory protein; Required for insertion of 4Fe-4S clusters. (124 aa)
iscSCysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (405 aa)
Rpic_0886TIGRFAM: iron-sulfur cluster assembly protein IscA; iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: rso:RSc1021 hypothetical protein; Belongs to the HesB/IscA family. (106 aa)
Rpic_0890TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: rso:RSc1025 probable ferredoxin [2Fe-2S] protein. (112 aa)
Rpic_0908PFAM: Rieske [2Fe-2S] domain protein; KEGG: rso:RSc1043 hypothetical protein. (130 aa)
Rpic_1354PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: rso:RSc1469 putative dehydrogenase oxidoreductase protein. (175 aa)
Rpic_1364PFAM: Rieske [2Fe-2S] domain protein; Aromatic-ring-hydroxylating dioxygenase, alpha subunit-like; KEGG: bch:Bcen2424_6524 Rieske (2Fe-2S) domain protein. (452 aa)
Rpic_1366PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: bmu:Bmul_3240 oxidoreductase FAD/NAD(P)-binding domain protein. (342 aa)
Rpic_1794Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (201 aa)
Rpic_2054PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: reu:Reut_C5888 ferredoxin:(2Fe-2S)-binding. (191 aa)
Rpic_2091PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: rso:RSc1890 probable isoquinoline 1-oxidoreductase (alpha subunit) oxidoreductase protein. (155 aa)
Rpic_2148KEGG: rso:RSc1993 succinate dehydrogenase iron-sulfur subunit; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (233 aa)
Rpic_2157Hypothetical protein; KEGG: rso:RSc2002 2-methylcitrate dehydratase. (132 aa)
Rpic_2208NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (783 aa)
Rpic_2210TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: rso:RSc2058 NADH dehydrogenase subunit E. (167 aa)
Rpic_2246TIGRFAM: xanthine dehydrogenase, small subunit; PFAM: ferredoxin; molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain protein; CO dehydrogenase flavoprotein domain protein; KEGG: rso:RSc2095 putative xanthine dehydrogenase (subunit A) oxidoreductase protein. (504 aa)
Rpic_2429PFAM: Rieske [2Fe-2S] domain protein; KEGG: rso:RSc2224 probable dioxygenase (alpha subunit) oxidoreductase protein. (365 aa)
Rpic_2513TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: bte:BTH_II0362 succinate dehydrogenase, iron-sulfur protein. (235 aa)
ilvDKEGG: rso:RSc2412 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (557 aa)
ilvD-2KEGG: bur:Bcep18194_B1899 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (619 aa)
Rpic_2702PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: rso:RSc2434 CDP-6-deoxy-delta-3,4-glucoseen reductase. (349 aa)
Rpic_3005PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: bmu:Bmul_3202 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (578 aa)
Rpic_3150TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: rso:RSc2904 hypothetical protein; Belongs to the glutaredoxin family. Monothiol subfamily. (103 aa)
Rpic_3158SMART: zinc finger CDGSH-type domain protein; KEGG: rso:RSc2912 hypothetical protein. (74 aa)
Rpic_3206Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (202 aa)
Rpic_3232PFAM: BolA family protein; KEGG: rso:RSc2954 hypothetical protein; Belongs to the BolA/IbaG family. (80 aa)
Rpic_3376PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: reu:Reut_B4505 twin-arginine translocation pathway signal. (246 aa)
Rpic_4082PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: bch:Bcen2424_6696 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (594 aa)
Rpic_4165TIGRFAM: nitrite reductase [NAD(P)H], small subunit; KEGG: rso:RSp1221 probable nitrite reductase NADPH (small subunit) oxidoreductase protein. (112 aa)
Rpic_4286Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: pfo:Pfl_0677 possible transcriptional regulator, MerR family. (133 aa)
Rpic_4359KEGG: rso:RSc1993 succinate dehydrogenase iron-sulfur subunit; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin. (233 aa)
Rpic_4510PFAM: Rieske [2Fe-2S] domain protein; KEGG: reu:Reut_B3570 Rieske (2Fe-2S) region. (355 aa)
Rpic_4563TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: rso:RSp0608 probable ferredoxin reductase protein. (364 aa)
Rpic_4625PFAM: ferredoxin; KEGG: reu:Reut_B5686 ferredoxin. (121 aa)
Rpic_4626PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: reu:Reut_B5685 ferredoxin:oxidoreductase FAD/NAD(P)-binding:oxidoreductase FAD-binding region. (354 aa)
Rpic_4634PFAM: Rieske [2Fe-2S] domain protein; KEGG: reu:Reut_B5677 Rieske (2Fe-2S) region. (111 aa)
Rpic_4637PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: reu:Reut_B5674 ferredoxin:oxidoreductase FAD/NAD(P)-binding:oxidoreductase FAD-binding region. (343 aa)
Rpic_4805PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: rso:RS05442 probable dehydrogenase, small chain oxidoreductase protein. (152 aa)
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.