STRINGSTRING
Rpic_0029 Rpic_0029 Rpic_0144 Rpic_0144 Rpic_0145 Rpic_0145 Rpic_0188 Rpic_0188 Rpic_0238 Rpic_0238 Rpic_0295 Rpic_0295 Rpic_0424 Rpic_0424 Rpic_0470 Rpic_0470 Rpic_0575 Rpic_0575 Rpic_0589 Rpic_0589 Rpic_0612 Rpic_0612 Rpic_0613 Rpic_0613 Rpic_0616 Rpic_0616 Rpic_0759 Rpic_0759 Rpic_0939 Rpic_0939 Rpic_0943 Rpic_0943 Rpic_1028 Rpic_1028 ntrC ntrC Rpic_1227 Rpic_1227 Rpic_1673 Rpic_1673 Rpic_1718 Rpic_1718 Rpic_1742 Rpic_1742 Rpic_1760 Rpic_1760 Rpic_1780 Rpic_1780 Rpic_1841 Rpic_1841 Rpic_1898 Rpic_1898 Rpic_1949 Rpic_1949 Rpic_2021 Rpic_2021 Rpic_2046 Rpic_2046 Rpic_2723 Rpic_2723 Rpic_2724 Rpic_2724 Rpic_2973 Rpic_2973 Rpic_2976 Rpic_2976 Rpic_2977 Rpic_2977 Rpic_3052 Rpic_3052 Rpic_3142 Rpic_3142 Rpic_3143 Rpic_3143 Rpic_3212 Rpic_3212 Rpic_3357 Rpic_3357 Rpic_3358 Rpic_3358 Rpic_3370 Rpic_3370 Rpic_3411 Rpic_3411 Rpic_3417 Rpic_3417 Rpic_3552 Rpic_3552 Rpic_3594 Rpic_3594 Rpic_3595 Rpic_3595 Rpic_3603 Rpic_3603 Rpic_3626 Rpic_3626 Rpic_3671 Rpic_3671 Rpic_3711 Rpic_3711 Rpic_3729 Rpic_3729 Rpic_3737 Rpic_3737 Rpic_3767 Rpic_3767 Rpic_3777 Rpic_3777 Rpic_3789 Rpic_3789 Rpic_3808 Rpic_3808 Rpic_4047 Rpic_4047 cheB cheB Rpic_4055 Rpic_4055 Rpic_4185 Rpic_4185 Rpic_4200 Rpic_4200 Rpic_4211 Rpic_4211 Rpic_4426 Rpic_4426 Rpic_4573 Rpic_4573 Rpic_4675 Rpic_4675 Rpic_4687 Rpic_4687 Rpic_4751 Rpic_4751 Rpic_4795 Rpic_4795 Rpic_4831 Rpic_4831 Rpic_4844 Rpic_4844 Rpic_4863 Rpic_4863 Rpic_4878 Rpic_4878
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rpic_0029PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: bvi:Bcep1808_3441 PAS/PAC sensor hybrid histidine kinase. (732 aa)
Rpic_0144PFAM: response regulator receiver; KEGG: rso:RSc0291 putative transcription regulator protein. (146 aa)
Rpic_0145Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; KEGG: rso:RSc0292 response regulator transcription regulator protein. (210 aa)
Rpic_0188Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: rso:RSc0332 probable C4-dicarboxylate transport response regulator transcription regulator protein. (438 aa)
Rpic_0238PFAM: ANTAR domain protein; KEGG: rso:RSc0382 probable response regulator transcription regulator protein. (212 aa)
Rpic_0295Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pol:Bpro_0543 two component transcriptional regulator, winged helix family. (242 aa)
Rpic_0424Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RSc0543 probable response regulator transcription regulator protein. (246 aa)
Rpic_0470Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RSc0550 probable response regulator transcription regulator protein. (236 aa)
Rpic_0575Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bmu:Bmul_5866 two component transcriptional regulator, winged helix family. (224 aa)
Rpic_0589PFAM: response regulator receiver; KEGG: reh:H16_A0712 flp pilus assembly ATPase. (402 aa)
Rpic_0612PFAM: response regulator receiver; KEGG: rso:RSc0668 probable twitching motility two-component response regulator transcription regulator protein. (152 aa)
Rpic_0613PFAM: response regulator receiver; KEGG: rso:RSc0669 putative twitching motility two-component response regulator transcription regulator protein. (122 aa)
Rpic_0616CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: rso:RSc0672 putative composite two component regulatory (sensor histidine kinase and response regulator hybrid) transcription regulator protein. (2009 aa)
Rpic_0759Multi-sensor hybrid histidine kinase; KEGG: bpd:BURPS668_A0191 sensor protein EvgS; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; SMART: extracellular solute-binding protein family 3. (818 aa)
Rpic_0939Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RSc1073 probable two-component system response regulator transcription regulator protein. (237 aa)
Rpic_0943Two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain protein; KEGG: rso:RSc1076 probable two-component system response regulator transcription regulator protein. (235 aa)
Rpic_1028Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; KEGG: rso:RSc1185 probable transcription regulator protein. (222 aa)
ntrCNitrogen metabolism transcriptional regulator, NtrC, Fis Family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (502 aa)
Rpic_1227PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: rso:RSc1352 probable two-component response regulator transcription regulator protein. (277 aa)
Rpic_1673Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Bacterio-opsin activator HTH domain protein; KEGG: rme:Rmet_5323 two component transcriptional regulator, LuxR family. (201 aa)
Rpic_1718TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RSp0655 probable two component response regulator transcription regulator protein. (228 aa)
Rpic_1742Two component heavy metal response transcriptional regulator, winged helix family; TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: reh:H16_B2186 response regulator of copper response,OmpR-family. (228 aa)
Rpic_1760TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rme:Rmet_5978 two component heavy metal response transcriptional regulator, winged helix family. (225 aa)
Rpic_1780TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RSp0655 probable two component response regulator transcription regulator protein. (228 aa)
Rpic_1841TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RSp0655 probable two component response regulator transcription regulator protein. (228 aa)
Rpic_1898Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RSc1648 osmolarity response regulator. (240 aa)
Rpic_1949Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: rso:RSc1597 probable response regulator transcription regulator protein. (211 aa)
Rpic_2021Two component transcriptional regulator, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RSc1534 probable phosphate regulon two-component response regulator transcription regulator protein. (237 aa)
Rpic_2046PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; KEGG: bam:Bamb_4255 transcriptional regulator, LuxR family. (219 aa)
Rpic_2723Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: rso:RSc2455 response regulator VSRC transcription regulator protein. (221 aa)
Rpic_2724Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rso:RSc2456 composite two-component regulatory (sensor kinase and response regulator hybrid) transcription regulator protein. (631 aa)
Rpic_2973PFAM: response regulator receiver; KEGG: rso:RSc2734 probable response regulator transcription regulator protein. (345 aa)
Rpic_2976PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rso:RSc2737 two component response regulator transcription regulator protein. (368 aa)
Rpic_2977PFAM: response regulator receiver; KEGG: rso:RSc2738 probable response regulator transcription regulator protein. (339 aa)
Rpic_3052Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: rso:RSc2807 probable response regulator transcription regulator protein. (541 aa)
Rpic_3142PFAM: response regulator receiver; KEGG: ppf:Pput_3340 response regulator receiver protein. (164 aa)
Rpic_3143KEGG: bxe:Bxe_A2317 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (652 aa)
Rpic_3212Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RSc2935 putative response regulator transcription regulator protein. (233 aa)
Rpic_3357Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: rso:RSc3078 probable response regulator transcription regulator protein. (222 aa)
Rpic_3358Multi-sensor hybrid histidine kinase; KEGG: rso:RSc3079 probable composite two component regulatory (sensor histidine kinase and response regulator hybrid) transcription regulator protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; extracellular solute-binding protein family 3. (1436 aa)
Rpic_3370Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RSc3087 probable response regulator transcription regulator protein. (234 aa)
Rpic_3411PFAM: regulatory protein LuxR; response regulator receiver; KEGG: bxe:Bxe_B2906 two component transcriptional regulator, LuxR family. (194 aa)
Rpic_3417PFAM: regulatory protein LuxR; response regulator receiver; KEGG: bam:Bamb_2835 two component transcriptional regulator, LuxR family. (232 aa)
Rpic_3552Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: reu:Reut_A3389 response regulator receiver:transcriptional regulatory protein, C-terminal. (236 aa)
Rpic_3594PFAM: EAL domain protein; response regulator receiver; KEGG: rso:RSc3387 probable two-component response regulator transcription regulator protein. (404 aa)
Rpic_3595Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; sigma-70 region 4 domain protein; KEGG: rso:RSc3388 probable two-component response regulator transcription regulator protein. (215 aa)
Rpic_3603Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RSc3392 probable response regulator transcription regulator protein. (226 aa)
Rpic_3626Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RSc3404 probable response regulator transcription regulator protein. (221 aa)
Rpic_3671PFAM: response regulator receiver; helix-turn-helix Fis-type; KEGG: rso:RSc0078 probable two component response regulator transcription regulator protein. (236 aa)
Rpic_3711Two component transcriptional regulator, Fis family; PFAM: response regulator receiver; helix-turn-helix Fis-type; KEGG: rso:RSc0040 probable response regulator transcription regulator protein. (192 aa)
Rpic_3729Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: bpl:BURPS1106A_A3133 DNA-binding response regulator, LuxR family. (214 aa)
Rpic_3737Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RSc0018 probable response regulator transcription regulator protein. (278 aa)
Rpic_3767Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: rso:RS02226 probable sigma-54 interacting response regulator transcription regulator protein. (468 aa)
Rpic_3777PAS/PAC sensor hybrid histidine kinase; KEGG: rso:RS02235 probable composite two-component regulatory (sensor kinase and response regulator hybrid) transcription regulator protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (794 aa)
Rpic_3789Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: rso:RSp0009 probable response regulator of the C4-dicarboxylate transport two-component regulatory system transcription regulator protein. (452 aa)
Rpic_3808Multi-sensor hybrid histidine kinase; KEGG: bte:BTH_II0144 sensor protein EvgS precursor; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; SMART: extracellular solute-binding protein family 3. (808 aa)
Rpic_4047PFAM: response regulator receiver; KEGG: rso:RSp1409 putative chemotaxis response regulator transcription regulator protein. (137 aa)
cheBResponse regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (375 aa)
Rpic_4055PFAM: response regulator receiver; KEGG: rso:RSp1402 probable chemotaxis response regulator transcription regulator protein. (133 aa)
Rpic_4185Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RS03140 probable two component response regulator transcription regulator protein. (243 aa)
Rpic_4200Multi-sensor hybrid histidine kinase; KEGG: rso:RS05068 probable composite two-component transcriptional regulatory (sensor histidine kinase and response regulator hybrid) transcription regulator protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein. (678 aa)
Rpic_4211Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RS05646 probable two-component response regulator transcription regulator protein. (219 aa)
Rpic_4426Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; KEGG: rso:RSc0192 probable response regulator transcription regulator protein. (215 aa)
Rpic_4573PFAM: response regulator receiver; CheW domain protein; KEGG: rso:RS03881 putative response regulator transcription regulator protein. (316 aa)
Rpic_4675Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Bacterio-opsin activator HTH domain protein; Sigma-70 region 4 type 2; KEGG: rso:RSp0980 probable nitrate/nitrite response regulator transcription regulator protein. (218 aa)
Rpic_4687Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RS00402 putative two component response regulator transcription regulator protein. (221 aa)
Rpic_4751Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; KEGG: rso:RS00809 probable transcription regulator protein. (211 aa)
Rpic_4795Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; LexA DNA-binding domain protein; KEGG: rso:RSp0338 negative regulator of exopolysaccharide production transcription regulator protein. (221 aa)
Rpic_4831PFAM: response regulator receiver; KEGG: bxe:Bxe_B3007 response regulator receiver domain protein(CheY). (121 aa)
Rpic_4844Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; KEGG: rso:RS03679 probable transcription regulator protein. (303 aa)
Rpic_4863Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RS02110 probable two-component response regulator transcription regulator protein. (244 aa)
Rpic_4878PFAM: ABC transporter transmembrane region; response regulator receiver; ABC transporter related; ATP-binding region ATPase domain protein; SMART: AAA ATPase; KEGG: bpt:Bpet2380 ABC transporter, ATP-binding protein. (991 aa)
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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