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parE parE Rpic_4048 Rpic_4048 Rpic_4186 Rpic_4186 Rpic_4200 Rpic_4200 Rpic_4210 Rpic_4210 Rpic_4393 Rpic_4393 Rpic_4427 Rpic_4427 Rpic_4650 Rpic_4650 Rpic_4674 Rpic_4674 Rpic_4686 Rpic_4686 Rpic_4834 Rpic_4834 Rpic_4862 Rpic_4862 Rpic_4878 Rpic_4878 gyrB gyrB Rpic_0029 Rpic_0029 Rpic_0142 Rpic_0142 Rpic_0187 Rpic_0187 Rpic_0294 Rpic_0294 Rpic_0469 Rpic_0469 Rpic_0576 Rpic_0576 Rpic_0616 Rpic_0616 Rpic_0759 Rpic_0759 Rpic_1759 Rpic_1759 Rpic_1741 Rpic_1741 Rpic_1717 Rpic_1717 Rpic_1674 Rpic_1674 Rpic_1226 Rpic_1226 Rpic_1088 Rpic_1088 Rpic_0941 Rpic_0941 Rpic_3929 Rpic_3929 htpG htpG Rpic_3143 Rpic_3143 Rpic_3141 Rpic_3141 Rpic_3053 Rpic_3053 Rpic_2976 Rpic_2976 Rpic_2975 Rpic_2975 mutL mutL Rpic_2724 Rpic_2724 Rpic_2020 Rpic_2020 Rpic_1948 Rpic_1948 Rpic_1899 Rpic_1899 Rpic_1842 Rpic_1842 Rpic_1781 Rpic_1781 Rpic_3213 Rpic_3213 Rpic_3358 Rpic_3358 Rpic_3424 Rpic_3424 Rpic_3553 Rpic_3553 Rpic_3592 Rpic_3592 Rpic_3604 Rpic_3604 Rpic_3625 Rpic_3625 Rpic_3672 Rpic_3672 Rpic_3712 Rpic_3712 Rpic_3728 Rpic_3728 Rpic_3777 Rpic_3777 Rpic_3788 Rpic_3788 Rpic_3808 Rpic_3808
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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parEDNA topoisomerase (ATP-hydrolyzing); Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (661 aa)
Rpic_4048CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheY binding; KEGG: rso:RSp1408 probable chemotaxis sensor histidine kinase transcription regulator protein. (724 aa)
Rpic_4186Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: rso:RS03139 probable two component transmembrane sensor kinase transcription regulator protein. (428 aa)
Rpic_4200Multi-sensor hybrid histidine kinase; KEGG: rso:RS05068 probable composite two-component transcriptional regulatory (sensor histidine kinase and response regulator hybrid) transcription regulator protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein. (678 aa)
Rpic_4210Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: rso:RS05645 probable two-component sensor histidine kinase transcription regulator protein. (518 aa)
Rpic_4393Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: bpm:BURPS1710b_1485 two-component hybrid sensor and regulator. (582 aa)
Rpic_4427Multi-sensor signal transduction histidine kinase; KEGG: rso:RSc0191 probable transmembrane two component system sensor kinase transcription regulator protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (462 aa)
Rpic_4650Multi-sensor signal transduction histidine kinase; KEGG: reu:Reut_A1215 PAS; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (466 aa)
Rpic_4674Multi-sensor signal transduction histidine kinase; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: rso:RSp0979 putative transmembrane nitrate/nitrite sensor kinase transcription regulator protein. (651 aa)
Rpic_4686Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: rso:RS00403 probable transmembrane sensor histidine kinase transcription regulator protein. (498 aa)
Rpic_4834Putative CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: PAC repeat-containing protein; KEGG: bxe:Bxe_B3011 CheA signal transduction histidine kinases (STHK). (794 aa)
Rpic_4862Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: rso:RS02109 probable transmembrane two-component sensor kinase transcription regulator protein. (438 aa)
Rpic_4878PFAM: ABC transporter transmembrane region; response regulator receiver; ABC transporter related; ATP-binding region ATPase domain protein; SMART: AAA ATPase; KEGG: bpt:Bpet2380 ABC transporter, ATP-binding protein. (991 aa)
gyrBDNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (842 aa)
Rpic_0029PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: bvi:Bcep1808_3441 PAS/PAC sensor hybrid histidine kinase. (732 aa)
Rpic_0142Multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; CHASE3 domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: rso:RSc0289 transmembrane sensor kinase VsrA transcription regulator protein. (485 aa)
Rpic_0187Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rso:RSc0331 probable C4-dicarboxylate transport sensor kinase transcription regulator protein. (672 aa)
Rpic_0294Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: pol:Bpro_0544 periplasmic sensor signal transduction histidine kinase. (498 aa)
Rpic_0469Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: rso:RSc0549 probable transmembrane sensor histidine kinase transcription regulator protein. (531 aa)
Rpic_0576Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: bmu:Bmul_5865 integral membrane sensor signal transduction histidine kinase. (458 aa)
Rpic_0616CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: rso:RSc0672 putative composite two component regulatory (sensor histidine kinase and response regulator hybrid) transcription regulator protein. (2009 aa)
Rpic_0759Multi-sensor hybrid histidine kinase; KEGG: bpd:BURPS668_A0191 sensor protein EvgS; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; SMART: extracellular solute-binding protein family 3. (818 aa)
Rpic_1759Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system. (476 aa)
Rpic_1741Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system. (461 aa)
Rpic_1717Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system. (465 aa)
Rpic_1674Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: rme:Rmet_5322 periplasmic sensor signal transduction histidine kinase. (535 aa)
Rpic_1226Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase internal region; KEGG: rso:RSc1351 putative transmembrane sensor histidine kinase transcription regulator protein. (422 aa)
Rpic_1088Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rso:RSc1260 probable nitrogen regulation (sensor protein kinase) transcription regulator. (400 aa)
Rpic_0941Multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CHASE2 domain protein; PAS fold-4 domain protein; KEGG: rso:RSc1075 probable two-component system sensor histidine kinase transcription regulator protein. (777 aa)
Rpic_3929Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: rso:RS05203 probable two-component transmembrane sensor histidine kinase transcription regulator protein. (461 aa)
htpGHeat shock protein Hsp90; Molecular chaperone. Has ATPase activity. (643 aa)
Rpic_3143KEGG: bxe:Bxe_A2317 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (652 aa)
Rpic_3141PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Phytochrome central region domain protein; PAS fold-2 domain protein; KEGG: psa:PST_4182 phytochrome family protein, putative. (762 aa)
Rpic_3053Multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: PAS domain containing protein; KEGG: rso:RSc2808 probable transmembrane sensor histidine kinase transcription regulator protein. (679 aa)
Rpic_2976PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rso:RSc2737 two component response regulator transcription regulator protein. (368 aa)
Rpic_2975PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rso:RSc2736 transmembrane sensor histidine kinase transcription regulator protein. (442 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (647 aa)
Rpic_2724Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rso:RSc2456 composite two-component regulatory (sensor kinase and response regulator hybrid) transcription regulator protein. (631 aa)
Rpic_2020Multi-sensor signal transduction histidine kinase; KEGG: rso:RSc1535 probable phosphate regulon two-component sensor kinase transcription regulator protein; TIGRFAM: phosphate regulon sensor kinase PhoR; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: PAS domain containing protein. (442 aa)
Rpic_1948KEGG: rso:RSc1598 probable two-component transmembrane sensor histidine kinase transcription regulator protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. (858 aa)
Rpic_1899Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: rso:RSc1647 probable oxidative stress resistance two-component transmembrane sensor histidine kinase transcription regulator protein. (453 aa)
Rpic_1842Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system. (456 aa)
Rpic_1781Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system. (465 aa)
Rpic_3213Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: rso:RSc2936 putative transmembrane sensor kinase transcription regulator protein. (509 aa)
Rpic_3358Multi-sensor hybrid histidine kinase; KEGG: rso:RSc3079 probable composite two component regulatory (sensor histidine kinase and response regulator hybrid) transcription regulator protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; extracellular solute-binding protein family 3. (1436 aa)
Rpic_3424KEGG: bvi:Bcep1808_1534 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. (378 aa)
Rpic_3553Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: reh:H16_A3681 signal transduction histidine kinase. (557 aa)
Rpic_3592PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Osmosensitive K channel His kinase sensor; KEGG: rso:RSc3385 probable two-component sensor kinase KdpD transcription regulator protein. (938 aa)
Rpic_3604Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: bxe:Bxe_B0497 histidine kinase. (483 aa)
Rpic_3625Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: rso:RSc3403 probable two-component sensor kinase transcription regulator protein. (439 aa)
Rpic_3672Multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: rso:RSc0077 probable two component sensor histidine kinase transcription regulator protein. (823 aa)
Rpic_3712PFAM: ATP-binding region ATPase domain protein; KEGG: rso:RSc0039 probable transmembrane sensor histidine kinase transcription regulator protein. (448 aa)
Rpic_3728Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; Cache type 2 domain protein; KEGG: rso:RSc0021 probable transmembrane sensor histidine kinase transcription regulator protein. (488 aa)
Rpic_3777PAS/PAC sensor hybrid histidine kinase; KEGG: rso:RS02235 probable composite two-component regulatory (sensor kinase and response regulator hybrid) transcription regulator protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (794 aa)
Rpic_3788Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rso:RSp0008 probable C4-dicarboxylate transport sensor kinase transcription regulator protein. (635 aa)
Rpic_3808Multi-sensor hybrid histidine kinase; KEGG: bte:BTH_II0144 sensor protein EvgS precursor; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; SMART: extracellular solute-binding protein family 3. (808 aa)
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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