STRINGSTRING
Rpic_0090 Rpic_0090 Rpic_0114 Rpic_0114 Rpic_0124 Rpic_0124 Rpic_0126 Rpic_0126 Rpic_0159 Rpic_0159 Rpic_0349 Rpic_0349 Rpic_0414 Rpic_0414 Rpic_0655 Rpic_0655 Rpic_0656 Rpic_0656 Rpic_0874 Rpic_0874 Rpic_1209 Rpic_1209 Rpic_1228 Rpic_1228 Rpic_1335 Rpic_1335 Rpic_1378 Rpic_1378 Rpic_1435 Rpic_1435 Rpic_1445 Rpic_1445 Rpic_1447 Rpic_1447 maiA maiA Rpic_1910 Rpic_1910 Rpic_1914 Rpic_1914 Rpic_1915 Rpic_1915 Rpic_1916 Rpic_1916 Rpic_1981 Rpic_1981 Rpic_1982 Rpic_1982 Rpic_1983 Rpic_1983 Rpic_2061 Rpic_2061 Rpic_2148 Rpic_2148 Rpic_2149 Rpic_2149 Rpic_2150 Rpic_2150 Rpic_2151 Rpic_2151 Rpic_2168 Rpic_2168 Rpic_2227 Rpic_2227 Rpic_2228 Rpic_2228 Rpic_2513 Rpic_2513 Rpic_2628 Rpic_2628 Rpic_3114 Rpic_3114 Rpic_3721 Rpic_3721 Rpic_3722 Rpic_3722 Rpic_4021 Rpic_4021 Rpic_4028 Rpic_4028 Rpic_4029 Rpic_4029 Rpic_4270 Rpic_4270 Rpic_4313 Rpic_4313 Rpic_4316 Rpic_4316 Rpic_4318 Rpic_4318 Rpic_4356 Rpic_4356 Rpic_4412 Rpic_4412 Rpic_4504 Rpic_4504 Rpic_4618 Rpic_4618 Rpic_4928 Rpic_4928 Rpic_4929 Rpic_4929
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rpic_0090PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: rso:RSc0244 3-hydroxybutyryl-CoA dehydrogenase. (284 aa)
Rpic_0114PFAM: pyruvate carboxyltransferase; KEGG: rso:RSc0261 hydroxymethylglutaryl-CoA lyase. (309 aa)
Rpic_0124PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: rso:RSc0274 putative acyl CoA dehydrogenase oxidoreductase protein. (376 aa)
Rpic_0126KEGG: rso:RSc0276 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Rpic_0159PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rso:RSc0304 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (272 aa)
Rpic_0349PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: rso:RSc0474 putative 3-hydroxyacyl-CoA dehydrogenase oxidoreductase protein. (826 aa)
Rpic_0414KEGG: bxe:Bxe_A2777 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (439 aa)
Rpic_0655TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: rme:Rmet_2699 acetyl-CoA synthetase. (684 aa)
Rpic_0656TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: mms:mma_2905 succinate-semialdehyde dehydrogenase (NADP+). (503 aa)
Rpic_0874TIGRFAM: polyhydroxyalkanoate depolymerase, intracellular; PFAM: PHB de-polymerase domain protein; KEGG: rso:RSc1008 probable poly[D(-)-3-hydroxybutyrate] depolymerase protein. (423 aa)
Rpic_1209Putative D--3-hydroxybutyrate oligomer hydrolase lipoprotein transmembrane; Participates in the degradation of poly-3-hydroxybutyrate (PHB). It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB- oligomers) into 3HB-monomers. (725 aa)
Rpic_1228PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: rso:RSc1353 acetolactate synthase 2 catalytic subunit; Belongs to the TPP enzyme family. (575 aa)
Rpic_1335Succinate CoA transferase; KEGG: reu:Reut_A1290 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. (515 aa)
Rpic_1378PFAM: pyruvate carboxyltransferase; KEGG: aav:Aave_1652 pyruvate carboxyltransferase. (331 aa)
Rpic_1435PFAM: iron-containing alcohol dehydrogenase; KEGG: rso:RSc1771 probable NAD-dependent 4-hydroxybutyrate dehydrogenase oxidoreductase protein. (382 aa)
Rpic_1445KEGG: rso:RSc1761 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
Rpic_1447PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: rso:RSc1759 probable trifunctional: enoyl-CoA hydratase and delta3-cis-delta2-trans-enoyl-CoA isomerase and 3-hydroxyacyl-CoA dehydrogenase oxidoreductase protein. (693 aa)
maiAAsp/Glu/hydantoin racemase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate. (250 aa)
Rpic_1910KEGG: rso:RSc1637 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
Rpic_1914TIGRFAM: acetoacetyl-CoA reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: reu:Reut_A1349 acetyacetyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
Rpic_1915TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: rso:RSc1632 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Rpic_1916TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class I; PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein; KEGG: rso:RSc1631 probable poly-beta-hydroxybutyrate polymerase transmembrane protein. (597 aa)
Rpic_1981TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rso:RSc1572 3-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)
Rpic_1982KEGG: dac:Daci_4265 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase. (211 aa)
Rpic_1983KEGG: pol:Bpro_1905 3-oxoacid CoA-transferase, subunit A; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase. (233 aa)
Rpic_2061PFAM: pyruvate carboxyltransferase; KEGG: reh:H16_B2494 hydroxymethylglutaryl-CoA lyase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (326 aa)
Rpic_2148KEGG: rso:RSc1993 succinate dehydrogenase iron-sulfur subunit; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (233 aa)
Rpic_2149KEGG: rso:RSc1994 succinate dehydrogenase flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (592 aa)
Rpic_2150TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: rso:RSc1995 putative transmembrane succinate dehydrogenase (hydrophobic membrane anchor subunit) oxidoreductase protein. (121 aa)
Rpic_2151TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: rso:RSc1996 putative transmembrane succinate dehydrogenase (cytochrome b-556 subunit) oxidoreductase protein. (136 aa)
Rpic_2168PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: rso:RSc2013 3-hydroxybutyryl-CoA dehydrogenase. (502 aa)
Rpic_2227TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: rso:RSc2076 acetolactate synthase 3 regulatory subunit. (163 aa)
Rpic_2228TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: rso:RSc2077 acetolactate synthase 3 catalytic subunit. (585 aa)
Rpic_2513TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: bte:BTH_II0362 succinate dehydrogenase, iron-sulfur protein. (235 aa)
Rpic_2628PFAM: Enoyl-CoA hydratase/isomerase; KEGG: azo:azo1927 probable enoyl-CoA hydratase. (261 aa)
Rpic_3114PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rso:RSc2872 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
Rpic_3721TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: rso:RSc0029 probable 4-aminobutyrate aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa)
Rpic_3722TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: rso:RSc0028 probable succinate-semialdehyde dehydrogenase oxidoreductase protein; Belongs to the aldehyde dehydrogenase family. (500 aa)
Rpic_4021PFAM: Asp/Glu/hydantoin racemase; KEGG: reu:Reut_A0046 Asp/Glu racemase. (242 aa)
Rpic_4028KEGG: fal:FRAAL3149 acetyl-CoA:acetoacetyl-CoA transferase, beta subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase. (224 aa)
Rpic_4029PFAM: coenzyme A transferase; KEGG: cbe:Cbei_2654 3-oxoacid CoA-transferase, A subunit. (254 aa)
Rpic_4270TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: rso:RS02396 3-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
Rpic_4313PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein; KEGG: eba:ebA5073 putative poly-beta-hydroxyalkanoate synthase. (582 aa)
Rpic_4316PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase; KEGG: har:HEAR1516 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase. (481 aa)
Rpic_4318TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: bur:Bcep18194_C6772 succinic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (499 aa)
Rpic_4356TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: rso:RSc1996 putative transmembrane succinate dehydrogenase (cytochrome b-556 subunit) oxidoreductase protein. (158 aa)
Rpic_4412TIGRFAM: acetoacetyl-CoA reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: reu:Reut_B3865 acetoacetyl-CoA reductase. (248 aa)
Rpic_4504PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reh:H16_B0735 acetolactate synthase large subunit; Belongs to the TPP enzyme family. (579 aa)
Rpic_4618Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (311 aa)
Rpic_4928acetyl-CoA acetyltransferase; KEGG: bte:BTH_I0061 beta-ketoadipyl CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
Rpic_4929PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: bte:BTH_I0062 fatty oxidation complex, alpha subunit. (708 aa)
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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