node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AJE42652.1 | AJE42653.1 | SNOD_23365 | SNOD_23370 | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
AJE42652.1 | AJE42669.1 | SNOD_23365 | SNOD_23460 | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.955 |
AJE42652.1 | AJE43155.1 | SNOD_23365 | SNOD_26330 | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate dehydrogenase; Catalyzes the formation of acetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.920 |
AJE42652.1 | ilvC | SNOD_23365 | SNOD_23375 | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
AJE42652.1 | ilvD | SNOD_23365 | SNOD_18810 | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.946 |
AJE42652.1 | leuA | SNOD_23365 | SNOD_11490 | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.959 |
AJE42652.1 | leuB | SNOD_23365 | SNOD_23415 | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.978 |
AJE42652.1 | leuC | SNOD_23365 | SNOD_23605 | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.864 |
AJE42652.1 | leuD | SNOD_23365 | SNOD_23610 | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.890 |
AJE42653.1 | AJE42652.1 | SNOD_23370 | SNOD_23365 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
AJE42653.1 | AJE42669.1 | SNOD_23370 | SNOD_23460 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.975 |
AJE42653.1 | AJE43155.1 | SNOD_23370 | SNOD_26330 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate dehydrogenase; Catalyzes the formation of acetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.997 |
AJE42653.1 | ilvC | SNOD_23370 | SNOD_23375 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
AJE42653.1 | ilvD | SNOD_23370 | SNOD_18810 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.940 |
AJE42653.1 | leuA | SNOD_23370 | SNOD_11490 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.987 |
AJE42653.1 | leuB | SNOD_23370 | SNOD_23415 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.997 |
AJE42653.1 | leuC | SNOD_23370 | SNOD_23605 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.948 |
AJE42653.1 | leuD | SNOD_23370 | SNOD_23610 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.971 |
AJE42669.1 | AJE42652.1 | SNOD_23460 | SNOD_23365 | Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.955 |
AJE42669.1 | AJE42653.1 | SNOD_23460 | SNOD_23370 | Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.975 |