STRINGSTRING
AJE38895.1 AJE38895.1 amphDIII amphDIII AJE39093.1 AJE39093.1 AJE39098.1 AJE39098.1 AJE39110.1 AJE39110.1 eno-2 eno-2 zwf zwf AJE39283.1 AJE39283.1 AJE39287.1 AJE39287.1 AJE39329.1 AJE39329.1 AJE39457.1 AJE39457.1 AJE39469.1 AJE39469.1 pfkA pfkA AJE39651.1 AJE39651.1 AJE39653.1 AJE39653.1 AJE39654.1 AJE39654.1 AJE39711.1 AJE39711.1 AJE39918.1 AJE39918.1 AJE40151.1 AJE40151.1 tal tal pgl pgl pgi pgi tpiA tpiA pgk pgk AJE40167.1 AJE40167.1 AJE40175.1 AJE40175.1 AJE40220.1 AJE40220.1 pfp pfp AJE40322.1 AJE40322.1 AJE40459.1 AJE40459.1 AJE40693.1 AJE40693.1 glmS glmS AJE40882.1 AJE40882.1 AJE40883.1 AJE40883.1 manA manA AJE40986.1 AJE40986.1 manB manB manC manC eno eno glmU glmU AJE41131.1 AJE41131.1 AJE41132.1 AJE41132.1 AJE41133.1 AJE41133.1 AJE41266.1 AJE41266.1 AJE41267.1 AJE41267.1 AJE41268.1 AJE41268.1 gpmA gpmA AJE41559.1 AJE41559.1 AJE41699.1 AJE41699.1 AJE41701.1 AJE41701.1 glmM glmM glmS-2 glmS-2 AJE42207.1 AJE42207.1 AJE42211.1 AJE42211.1 AJE42260.1 AJE42260.1 AJE42301.1 AJE42301.1 AJE42306.1 AJE42306.1 nagB nagB AJE42579.1 AJE42579.1 pfkA-2 pfkA-2 AJE42923.1 AJE42923.1 AJE43048.1 AJE43048.1 AJE43148.1 AJE43148.1 AJE43183.1 AJE43183.1 AJE43261.1 AJE43261.1 AJE43305.1 AJE43305.1 AJE43483.1 AJE43483.1 AJE43484.1 AJE43484.1 zwf-2 zwf-2 AJE43751.1 AJE43751.1 AJE43767.1 AJE43767.1 AJE43768.1 AJE43768.1 AJE43769.1 AJE43769.1 AJE43770.1 AJE43770.1 AJE43805.1 AJE43805.1 AJE43915.1 AJE43915.1 AJE43942.1 AJE43942.1 AJE43963.1 AJE43963.1 AJE43964.1 AJE43964.1 AJE43965.1 AJE43965.1 AJE43974.1 AJE43974.1 AJE44186.1 AJE44186.1 AJE44372.1 AJE44372.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJE38895.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)
amphDIIIAmphDIII GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (344 aa)
AJE39093.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
AJE39098.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
AJE39110.1Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
eno-2Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (423 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (458 aa)
AJE39283.1ROK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
AJE39287.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
AJE39329.1Phosphoketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (793 aa)
AJE39457.1DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
AJE39469.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
AJE39651.1Mannose-1-phosphate guanyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (831 aa)
AJE39653.1PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
AJE39654.1Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (556 aa)
AJE39711.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
AJE39918.1Gluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
AJE40151.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (695 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (372 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (260 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (551 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (258 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (403 aa)
AJE40167.1Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
AJE40175.1Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
AJE40220.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
AJE40322.1Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
AJE40459.1Keto-deoxy-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
AJE40693.1Catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
glmSGlutamine amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (605 aa)
AJE40882.1PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (77 aa)
AJE40883.1PTS lactose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
manAMannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
AJE40986.1Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
manBPhosphomannomutase; Converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
manCGDP-mannose pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (482 aa)
AJE41131.1PTS lactose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (700 aa)
AJE41132.1Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (317 aa)
AJE41133.1D-beta-D-heptose 1-phosphate adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
AJE41266.1ROK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
AJE41267.1N-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
AJE41268.1Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (309 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (253 aa)
AJE41559.16-phosphogluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
AJE41699.1Aldose epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
AJE41701.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (343 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (452 aa)
glmS-2Glutamine amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (615 aa)
AJE42207.1Phosphomannomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (552 aa)
AJE42211.1DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
AJE42260.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
AJE42301.1Fructose 1,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
AJE42306.1Polyphosphate glucokinase; Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. (261 aa)
AJE42579.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
AJE42923.1Phosphocarrier protein HPr; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
AJE43048.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
AJE43148.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
AJE43183.1Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
AJE43261.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (615 aa)
AJE43305.1ROK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
AJE43483.16-phosphogluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
AJE43484.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
zwf-2Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (520 aa)
AJE43751.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa)
AJE43767.1Glucose dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (319 aa)
AJE43768.1Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
AJE43769.1N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (227 aa)
AJE43770.1Sialic acid transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)
AJE43805.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
AJE43915.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
AJE43942.1ROK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
AJE43963.1Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
AJE43964.1Sugar isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
AJE43965.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
AJE43974.1Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
AJE44186.1Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (481 aa)
AJE44372.1Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
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