(10 nodes) Formate metabolic process, and Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines network (Streptomyces nodosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hutI	Imidazolonepropionase; Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
	AJE41021.1	N-formimino-L-glutamate deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
	AJE41022.1	Allantoate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
	hutU	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (554 aa)
	AJE41025.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
	AJE41026.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
	AJE41027.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
	AJE41320.1	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
	hutH	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
	AJE43093.1	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)

Your Current Organism:

Streptomyces nodosus

NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJE41021.1	AJE41022.1	SNOD_13925	SNOD_13930	N-formimino-L-glutamate deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Allantoate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.972
AJE41021.1	AJE41025.1	SNOD_13925	SNOD_13945	N-formimino-L-glutamate deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.659
AJE41021.1	AJE41026.1	SNOD_13925	SNOD_13950	N-formimino-L-glutamate deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.659
AJE41021.1	AJE41027.1	SNOD_13925	SNOD_13955	N-formimino-L-glutamate deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.650
AJE41021.1	AJE43093.1	SNOD_13925	SNOD_25960	N-formimino-L-glutamate deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.482
AJE41021.1	hutH	SNOD_13925	SNOD_20915	N-formimino-L-glutamate deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.566
AJE41021.1	hutI	SNOD_13925	SNOD_13920	N-formimino-L-glutamate deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Imidazolonepropionase; Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.968
AJE41021.1	hutU	SNOD_13925	SNOD_13935	N-formimino-L-glutamate deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.905
AJE41022.1	AJE41021.1	SNOD_13930	SNOD_13925	Allantoate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	N-formimino-L-glutamate deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.972
AJE41022.1	AJE41025.1	SNOD_13930	SNOD_13945	Allantoate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.659
AJE41022.1	AJE41026.1	SNOD_13930	SNOD_13950	Allantoate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.659
AJE41022.1	AJE41027.1	SNOD_13930	SNOD_13955	Allantoate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.650
AJE41022.1	hutI	SNOD_13930	SNOD_13920	Allantoate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Imidazolonepropionase; Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.832
AJE41022.1	hutU	SNOD_13930	SNOD_13935	Allantoate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.783
AJE41025.1	AJE41021.1	SNOD_13945	SNOD_13925	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	N-formimino-L-glutamate deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.659
AJE41025.1	AJE41022.1	SNOD_13945	SNOD_13930	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Allantoate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.659
AJE41025.1	AJE41026.1	SNOD_13945	SNOD_13950	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.957
AJE41025.1	AJE41027.1	SNOD_13945	SNOD_13955	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.936
AJE41025.1	hutI	SNOD_13945	SNOD_13920	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Imidazolonepropionase; Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.647
AJE41025.1	hutU	SNOD_13945	SNOD_13935	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.686

page 1 of 4

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Databases

Fusion

Textmining

Cooccurrence

Experiments

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About