42 items (Streptomyces nodosus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AJE41363.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
	AJE42735.1	Signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (307 aa)
	AJE42733.1	Signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (239 aa)
	AJE42594.1	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family. (400 aa)
	lon	Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (811 aa)
	AJE42415.1	PDZ/DHR/GLGF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
	AJE42368.1	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (626 aa)
	AJE42225.1	Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family. (1099 aa)
	AJE41998.1	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
	AJE41750.1	Colicin V synthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
	AJE41576.1	Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
	AJE41480.1	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
	AJE41388.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
	AJE40908.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
	AJE40701.1	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family. (1108 aa)
	clpP-2	Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (207 aa)
	AJE40572.1	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
	AJE40413.1	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (646 aa)
	AJE40374.1	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
	AJE40358.1	Signal protein PDZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
	AJE40334.1	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
	AJE40228.1	Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
	AJE40041.1	Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family. (509 aa)
	AJE39834.1	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
	AJE39832.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
	clpP	Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (211 aa)
	AJE39365.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (139 aa)
	AJE39363.1	Integral membrane family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
	AJE39117.1	Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family. (401 aa)
	AJE44451.1	Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family. (1141 aa)
	clpP-4	Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (212 aa)
	clpP-3	Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (200 aa)
	AJE43823.1	Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
	AJE43755.1	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
	AJE43212.1	Peptidase S54 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
	AJE43060.1	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
	AJE42903.1	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
	lexA	LexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (259 aa)
	AJE42826.1	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
	AJE42823.1	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
	AJE42817.1	Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family. (406 aa)
	AJE42736.1	Signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (247 aa)

Your Current Organism:

Streptomyces nodosus

NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJE39117.1	AJE42823.1	SNOD_03000	SNOD_24340	Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.731
AJE39117.1	AJE42903.1	SNOD_03000	SNOD_24805	Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.664
AJE39363.1	AJE40358.1	SNOD_04445	SNOD_10115	Integral membrane family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Signal protein PDZ; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.421
AJE39363.1	AJE40374.1	SNOD_04445	SNOD_10210	Integral membrane family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.421
AJE39363.1	AJE41363.1	SNOD_04445	SNOD_15955	Integral membrane family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.421
AJE39363.1	AJE41480.1	SNOD_04445	SNOD_16735	Integral membrane family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.421
AJE39363.1	AJE41750.1	SNOD_04445	SNOD_18275	Integral membrane family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Colicin V synthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.421
AJE39363.1	AJE42368.1	SNOD_04445	SNOD_21755	Integral membrane family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.421
AJE39365.1	AJE42903.1	SNOD_04460	SNOD_24805	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.664
AJE39832.1	AJE39834.1	SNOD_07220	SNOD_07230	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.577
AJE39832.1	AJE42903.1	SNOD_07220	SNOD_24805	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.664
AJE39834.1	AJE39832.1	SNOD_07230	SNOD_07220	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.577
AJE39834.1	AJE42903.1	SNOD_07230	SNOD_24805	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.664
AJE40041.1	AJE42823.1	SNOD_08365	SNOD_24340	Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.766
AJE40041.1	AJE42903.1	SNOD_08365	SNOD_24805	Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.726
AJE40228.1	AJE40334.1	SNOD_09420	SNOD_09990	Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.541
AJE40228.1	AJE43060.1	SNOD_09420	SNOD_25770	Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.650
AJE40228.1	AJE43212.1	SNOD_09420	SNOD_26685	Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidase S54 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.434
AJE40334.1	AJE40228.1	SNOD_09990	SNOD_09420	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.541
AJE40334.1	AJE41576.1	SNOD_09990	SNOD_17255	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.732

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