(6 nodes) Histidine catabolic process to glutamate and formamide network (Streptomyces nodosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AJE40088.1	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
	hutI	Imidazolonepropionase; Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
	hutU	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (554 aa)
	AJE41320.1	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
	hutH	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
	AJE43093.1	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)

Your Current Organism:

Streptomyces nodosus

NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJE40088.1	AJE43093.1	SNOD_08630	SNOD_25960	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.754
AJE40088.1	hutH	SNOD_08630	SNOD_20915	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.754
AJE40088.1	hutU	SNOD_08630	SNOD_13935	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.908
AJE41320.1	AJE43093.1	SNOD_15705	SNOD_25960	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.754
AJE41320.1	hutH	SNOD_15705	SNOD_20915	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.754
AJE41320.1	hutU	SNOD_15705	SNOD_13935	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.908
AJE43093.1	AJE40088.1	SNOD_25960	SNOD_08630	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.754
AJE43093.1	AJE41320.1	SNOD_25960	SNOD_15705	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.754
AJE43093.1	hutH	SNOD_25960	SNOD_20915	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.922
AJE43093.1	hutI	SNOD_25960	SNOD_13920	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Imidazolonepropionase; Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.967
AJE43093.1	hutU	SNOD_25960	SNOD_13935	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.998
hutH	AJE40088.1	SNOD_20915	SNOD_08630	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.754
hutH	AJE41320.1	SNOD_20915	SNOD_15705	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.754
hutH	AJE43093.1	SNOD_20915	SNOD_25960	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.922
hutH	hutI	SNOD_20915	SNOD_13920	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Imidazolonepropionase; Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.979
hutH	hutU	SNOD_20915	SNOD_13935	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.999
hutI	AJE43093.1	SNOD_13920	SNOD_25960	Imidazolonepropionase; Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.967
hutI	hutH	SNOD_13920	SNOD_20915	Imidazolonepropionase; Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.979
hutI	hutU	SNOD_13920	SNOD_13935	Imidazolonepropionase; Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.999
hutU	AJE40088.1	SNOD_13935	SNOD_08630	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.908

page 1 of 2

Server load: low (24%) [HD]

Permalink

Network

Neighborhood

Databases

Fusion

Textmining

Cooccurrence

Experiments

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About